Uniprot accession / id : P35980  OR   Uniprot accession / id : Q07020  OR   Uniprot accession / id : F8VUA6
 
Filter by :
Entry Information
Entry status  (1)
REL
(121)
 
Experimental methods  (1)
Electron Microscopy
(121)
 
Authors  (361)
Klinge S
(24)
Vanden Broeck A
(24)
Beckmann R
(23)
Li Y
(17)
Cheng J
(16)
Gao N
(15)
Li N
(15)
Liang X
(15)
Ma C
(15)
Zhang Y
(15)
Buschauer R
(14)
Denk T
(12)
Natchiar SK
(12)
Becker T
(11)
Chen Y
(11)
Luo S
(11)
Berninghausen O
(9)
Myasnikov AG
(9)
Yokoyama T
(9)
Cate JHD
(8)
Chang ST
(8)
Kratzat H
(8)
Li W
(8)
Li X
(8)
Ward FR
(8)
Wei Z
(8)
Yong X
(8)
Dullea RG
(7)
Klaholz BP
(7)
Liras S
(7)
Mackens-Kiani T
(7)
McClure KF
(7)
Montabana E
(7)
Shirouzu M
(7)
Altman RB
(6)
Blanchard SC
(6)
Holm M
(6)
Natchiar KS
(6)
Rundlet EJ
(6)
Suzuki T
(6)
Taunton J
(6)
Wang HY
(6)
Wang M
(6)
Watson ZL
(6)
Iwasaki S
(5)
Kulathu Y
(5)
Peter JJ
(5)
Thoms M
(5)
Akichika S
(4)
Ameismeier M
(4)
Bhaskar V
(4)
Cavadini S
(4)
Chao JA
(4)
DaRosa PA
(4)
Dong M
(4)
Dong MQ
(4)
Frohlich T
(4)
Fröhlich T
(4)
Graff-Meyer A
(4)
Gumbin SC
(4)
Harper JW
(4)
Hayn M
(4)
Hirschenberger M
(4)
Irie T
(4)
Ishibashi K
(4)
Ishiguro K
(4)
Ito T
(4)
Kirchhoff F
(4)
Koepke L
(4)
Kopito R
(4)
Kopito RR
(4)
Ma D
(4)
Matsuzawa I
(4)
Mishima Y
(4)
Mito M
(4)
Ordureau A
(4)
Paulo JA
(4)
Penchev I
(4)
Saito H
(4)
Sakaguchi Y
(4)
Scavone F
(4)
Schenk AD
(4)
Sparrer KMJ
(4)
Straub JH
(4)
Sturzel CM
(4)
Stürzel CM
(4)
Takahashi M
(4)
Wachalska M
(4)
Wakabayashi K
(4)
Wąchalska M
(4)
Zhao X
(4)
Zuo M
(4)
Zuo MQ
(4)
von Loeffelholz O
(4)
Artus-Revel CG
(3)
Best K
(3)
Bretones G
(3)
Burger J
(3)
Bürger J
(3)
Gilbert W
(3)
 
More...
 
Homo / hetero assembly  (1)
hetero
(121)
 
Assembly composition  (1)
RNA/protein complex
(121)
 
Assembly polymer count  (36)
83-mer
(11)
85-mer
(10)
86-mer
(9)
80-mer
(8)
81-mer
(7)
50-mer
(6)
53-mer
(6)
84-mer
(6)
48-mer
(5)
54-mer
(5)
45-mer
(4)
46-mer
(3)
51-mer
(3)
52-mer
(3)
56-mer
(3)
59-mer
(3)
79-mer
(3)
82-mer
(3)
43-mer
(2)
47-mer
(2)
58-mer
(2)
78-mer
(2)
88-mer
(2)
162-mer
(1)
171-mer
(1)
172-mer
(1)
31-mer
(1)
44-mer
(1)
49-mer
(1)
61-mer
(1)
62-mer
(1)
63-mer
(1)
65-mer
(1)
87-mer
(1)
89-mer
(1)
92-mer
(1)
 
Resolution distribution
1.5 - 2
(6)
2.0 - 2.5
(13)
2.5 - 3
(52)
3.0 - 3.5
(36)
3.5 - 4
(11)
4.0 - 4.5
(2)
4.5 - 5
(1)
 
Release year distribution
2010 - 2015
(3)
2015 - 2020
(35)
2020 - 2025
(105)
2025 - 2030
(8)
 
Journal  (18)
Science
(29)
Nature
(17)
Nat Commun
(16)
Cell Res
(11)
To be published
(10)
Nat Struct Mol Biol
(8)
Cell
(5)
Cell Rep
(5)
Mol Cell
(4)
PLoS Biol
(3)
Cancer Discov
(2)
Elife
(2)
Front Mol Biosci
(2)
J Biochem
(2)
bioRxiv
(2)
Nat Chem Biol
(1)
Nucleic Acids Res
(1)
RNA
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(121)
 
Organism name  (3)
Homo sapiens
(114)
Mus musculus
(5)
Oryctolagus cuniculus
(2)
 
Molecule name  (2)
60S ribosomal protein L18
(121)
Large ribosomal subunit protein eL18
(121)
 
Molecule type  (1)
Protein
(121)
 
Gene names  (2)
RPL18
(116)
Rpl18
(5)
 
Interacting Molecules  (300)
Large ribosomal subunit protein eL14
(121)
Large ribosomal subunit protein eL20
(121)
Large ribosomal subunit protein eL21
(121)
Large ribosomal subunit protein eL32
(121)
Large ribosomal subunit protein eL33
(121)
Large ribosomal subunit protein uL13
(121)
Large ribosomal subunit protein uL30
(121)
Large ribosomal subunit protein uL4
(121)
Large ribosomal subunit protein eL36
(120)
Large ribosomal subunit protein eL6
(120)
Large ribosomal subunit protein eL8
(120)
Large ribosomal subunit protein uL22
(120)
Large ribosomal subunit protein uL29
(120)
Large ribosomal subunit protein uL3
(120)
Large ribosomal subunit protein eL15
(119)
Large ribosomal subunit protein eL37
(119)
Large ribosomal subunit protein uL14
(119)
Large ribosomal subunit protein uL15
(119)
Large ribosomal subunit protein uL23
(119)
Large ribosomal subunit protein uL6
(119)
Large ribosomal subunit protein uL24
(118)
Large ribosomal subunit protein eL13
(117)
Large ribosomal subunit protein eL28
(117)
28S ribosomal RNA
(114)
Large ribosomal subunit protein eL31
(113)
Large ribosomal subunit protein eL30
(111)
Large ribosomal subunit protein eL34
(111)
5.8S ribosomal RNA
(110)
Large ribosomal subunit protein eL19
(110)
Large ribosomal subunit protein eL38
(110)
Large ribosomal subunit protein eL43
(110)
Large ribosomal subunit protein uL18
(110)
Large ribosomal subunit protein uL5
(110)
Large ribosomal subunit protein eL22
(109)
Large ribosomal subunit protein eL39
(108)
Large ribosomal subunit protein eL27
(107)
Large ribosomal subunit protein uL2
(104)
5S ribosomal RNA
(102)
Large ribosomal subunit protein eL29
(101)
Large ribosomal subunit protein eL42
(86)
Large ribosomal subunit protein eL24
(82)
Small ribosomal subunit protein eS32
(70)
Small ribosomal subunit protein RACK1
(67)
Small ribosomal subunit protein eS1
(67)
Small ribosomal subunit protein eS19
(67)
Small ribosomal subunit protein eS21
(67)
Small ribosomal subunit protein eS28
(67)
Small ribosomal subunit protein eS6
(67)
Small ribosomal subunit protein eS7
(67)
Small ribosomal subunit protein eS8
(67)
Small ribosomal subunit protein uS14
(67)
Small ribosomal subunit protein uS15
(67)
Small ribosomal subunit protein uS3
(67)
Small ribosomal subunit protein uS4
(67)
Small ribosomal subunit protein uS7
(67)
Small ribosomal subunit protein uS8
(67)
Small ribosomal subunit protein eS10
(66)
Small ribosomal subunit protein eS26
(66)
Small ribosomal subunit protein uS10
(66)
Small ribosomal subunit protein uS13
(66)
Small ribosomal subunit protein uS17
(66)
Small ribosomal subunit protein uS19
(66)
Small ribosomal subunit protein uS9
(66)
Small ribosomal subunit protein eS24
(65)
Small ribosomal subunit protein eS25
(65)
Small ribosomal subunit protein uS11
(65)
Small ribosomal subunit protein uS2
(65)
Small ribosomal subunit protein uS5
(65)
Small ribosomal subunit protein eS27
(63)
Small ribosomal subunit protein eS17
(62)
Small ribosomal subunit protein uS12
(61)
18S Ribosomal RNA
(60)
Large ribosomal subunit protein uL1
(57)
Small ribosomal subunit protein eS4, X isoform
(57)
Small ribosomal subunit protein eS12
(55)
Small ribosomal subunit protein eS30
(53)
Large ribosomal subunit protein uL11
(52)
Ubiquitin-ribosomal protein eL40 fusion protein
(51)
Ribosomal protein uL16-like
(48)
Eukaryotic translation initiation factor 6
(46)
GTP-binding protein 4
(38)
Probable ribosome biogenesis protein RLP24
(38)
Ubiquitin-ribosomal protein eS31 fusion protein
(37)
Protein LLP homolog
(34)
mRNA turnover protein 4 homolog
(34)
Large ribosomal subunit protein uL16
(32)
Large ribosomal subunit protein uL10
(28)
Messenger RNA
(28)
Ribosome biogenesis protein NSA2 homolog
(27)
Pescadillo homolog
(25)
Ribosomal protein uL30-like
(25)
Zinc finger protein 593
(25)
MKI67 FHA domain-interacting nucleolar phosphoprotein
(24)
Nucleolar GTP-binding protein 2
(22)
Large ribosomal subunit protein eL40
(21)
tRNA
(21)
Guanine nucleotide-binding protein-like 3
(20)
Ribosomal L1 domain-containing protein 1
(20)
Proliferation-associated protein 2G4
(19)
Small ribosomal subunit protein eS31
(19)
 
More...
 
Interacting ligands  (4)
MG : MAGNESIUM ION
(11)
SPD : SPERMIDINE
(6)
PUT : 1,4-DIAMINOBUTANE
(4)
K : POTASSIUM ION
(3)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
...
Entries 1 to 10 of 121
Entries 1 to 10 of 121
 Select all entries on this page
Human nuclear pre-60S ribosomal subunit (State I3)
Vanden Broeck A, Klinge S
Science (2023) [PMID: 37410842  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: GDP    K    K    MG    ZN    GTP    ZN    GDP    GTP    MG   
Modified residues: A2M    OMC    OMG    5MC    6MZ    HIC    OMU    5MC    UR3    6MZ    A2M    1MA    HIC    1MA    PSU    PSU    OMC    OMG    OMU    UR3   
PDBe complex ID: PDB-CPX-221150 (Preferred)   search this ID
PDBe-KB: Q07020    P40429    P46779    Q9NVU7    Q8IZL8    P32969    (view 51 more)
Electron Microscopy
2.89Å resolution
Released: 12 Jul 2023
Model geometry
Fit model/data
Data not analysed
8fl4
8fl4
8fl4
Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline
Li X, Wang M, Denk T, Cheng J
Nat Commun (2024) [PMID: 38942792  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG    T1C    T1C   
Modified residues: MLZ    MLZ   
PDBe complex ID: PDB-CPX-272333 (Preferred)   search this ID
PDBe-KB: Q07020    P32969    P40429    P46779    P62753    P62081    (view 71 more)
Electron Microscopy
2Å resolution
Released: 10 Jul 2024
Model geometry
Fit model/data
Data not analysed
8yoo
8yoo
8yoo
In situ human top-back di-ribosome structure (Composite map)
Wei Z, Yong Z
To be published
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
Modified residues: N    N   
PDBe complex ID: PDB-CPX-290437 (Preferred)   search this ID
PDBe-KB: Q07020    P32969    P40429    P46779    P62753    P62081    (view 73 more)
Electron Microscopy
3.2Å resolution
Released: 19 Mar 2025
Model geometry
Fit model/data
Data not analysed
9b0q
9b0q
9b0q
Human nucleolar pre-60S ribosomal subunit (State H)
Vanden Broeck A, Klinge S
Science (2023) [PMID: 37410842  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: GDP    K    K    MG    ZN    GTP    ZN    GDP    GTP    MG   
Modified residues: HIC    HIC   
PDBe complex ID: PDB-CPX-271926 (Preferred)   search this ID
PDBe-KB: Q07020    P40429    P46779    P32969    Q15050    Q13823    (view 23 more)
Electron Microscopy
2.91Å resolution
Released: 12 Jul 2023
Model geometry
Fit model/data
Data not analysed
8fl0
8fl0
8fl0
Human nucleolar pre-60S ribosomal subunit (State A1)
Vanden Broeck A, Klinge S
Science (2023) [PMID: 37410842  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
Modified residues: AME    SEP    HIC    HIC    SEP    AME   
PDBe complex ID: PDB-CPX-221154 (Preferred)   search this ID
PDBe-KB: Q07020    P40429    O75683    Q9BYG3    Q15050    P26373    (view 38 more)
Electron Microscopy
2.85Å resolution
Released: 12 Jul 2023
Model geometry
Fit model/data
Data not analysed
8fkp
8fkp
8fkp
Human nucleolar pre-60S ribosomal subunit (State C2)
Vanden Broeck A, Klinge S
Science (2023) [PMID: 37410842  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: GDP    K    K    MG    ZN    ADP    ADP    ZN    GDP    MG   
Modified residues: SEP    HIC    HIC    SEP   
PDBe complex ID: PDB-CPX-271474 (Preferred)   search this ID
PDBe-KB: Q07020    P40429    P46779    P32969    Q9BYG3    Q15050    (view 41 more)
Electron Microscopy
2.82Å resolution
Released: 12 Jul 2023
Model geometry
Fit model/data
Data not analysed
8fku
8fku
8fku
80S ribosome from mouse bound to eEF2 (Class I)
Loerch S, Smith PR, Kunder N, Stanowick AD, Lou T-F, Campbell ZT
Nat Commun (2021) [PMID: 34815424  ]
Source organism: Mus musculus  
Assembly composition: RNA/protein complex
Bound ligands: GDP    MG    ZN    ZN    GDP    MG   
Modified residues: 4AC    A2M    B8N    B8Q    B8W    E7G    MLZ    OMC    OMG    5MC    6MZ    B9H    OMU    G7M    P7G    5MC    DDE    E6G    G7M    I4U    MHG    UR3    2MG    4AC    6MZ    A2M    1MA    MLZ    1MA    2MG    B8T    B9B    DDE    PSU    PSU    OMC    OMG    OMU    UR3   
PDBe complex ID: PDB-CPX-236911 (Preferred)   search this ID
PDBe-KB: P35980    Q9CY58    Q9CZX8    Q9D8E6    P62855    Q6ZWN5    (view 74 more)
Electron Microscopy
3.1Å resolution
Released: 3 Nov 2021
Model geometry
Fit model/data
Data not analysed
7ls2
7ls2
7ls2
Human nucleolar pre-60S ribosomal subunit (State B2)
Vanden Broeck A, Klinge S
Science (2023) [PMID: 37410842  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: GDP    K    K    MG    ZN    ZN    GDP    MG   
Modified residues: SEP    HIC    HIC    SEP   
PDBe complex ID: PDB-CPX-271471 (Preferred)   search this ID
PDBe-KB: Q07020    P40429    P46779    O75683    P32969    Q9BYG3    (view 38 more)
Electron Microscopy
2.88Å resolution
Released: 12 Jul 2023
Model geometry
Fit model/data
Data not analysed
8fks
8fks
8fks
In situ human Hibernating class4 80S ribosome
Wei Z, Yong X
To be published
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
PDBe complex ID: PDB-CPX-290434 (Preferred)   search this ID
PDBe-KB: Q07020    P32969    P40429    P46779    P62753    P62081    (view 72 more)
Electron Microscopy
2.57Å resolution
Released: 19 Mar 2025
Model geometry
Fit model/data
Data not analysed
9b0g
9b0g
9b0g
human nuclear pre-60S ribosomal particle - State E
Zhang Y, Gao N
Cell Res (2023) [PMID: 37491604  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Modified residues: A2M    B8Q    B8W    E7G    OMC    OMG    6MZ    B9H    OMU    P7G    E6G    I4U    MHG    UR3    2MG    5MU    5MU    6MZ    A2M    1MA    7MG    BGH    1MA    2MG    7MG    B8T    B9B    P4U    B8K    M7A    OMC    OMG    OMU    UR3   
PDBe complex ID: PDB-CPX-224865 (Preferred)   search this ID
PDBe-KB: Q07020    P32969    P40429    P46779    Q13823    P26373    (view 39 more)
Electron Microscopy
3.3Å resolution
Released: 9 Aug 2023
Model geometry
Fit model/data
Data not analysed
8ie3
8ie3
8ie3
...
Entries 1 to 10 of 121
Entries 1 to 10 of 121