Entry status  (1)

REL

(26)

Experimental methods  (2)

X-ray diffraction

(23)

Electron Microscopy

(3)

Authors  (52)

Tumbale PP

(11)

Williams RS

(11)

Caglayan M

(10)

O'Brien PJ

(10)

Çağlayan M

(10)

Jurkiw TJ

(9)

Schellenberg MJ

(9)

Gulkis M

(8)

Almohdar D

(7)

Balu KE

(7)

KanalElamparithi B

(7)

Riccio AA

(7)

Tumbale PS

(7)

Tang Q

(5)

Blair K

(3)

Creuhet R

(3)

Cruehet R

(3)

De Biasio A

(3)

Hamdan S

(3)

Hamdan SM

(3)

Lancey C

(3)

McKenna R

(3)

Raducanu VS

(3)

Rashid F

(3)

Shahid T

(3)

Tehseen M

(3)

Arana ME

(2)

Cunningham-Rundles C

(2)

Kalaycioglu M

(2)

Kalaycioğlu M

(2)

Kunkel TA

(2)

Rana JA

(2)

Ratcliffe J

(2)

Schellenberg MS

(2)

Williams JS

(2)

Ando T

(1)

Arita K

(1)

Defossez PA

(1)

Dohmae N

(1)

Ellenberger T

(1)

Ferry L

(1)

Jimenji T

(1)

Kodera N

(1)

Kori S

(1)

Matano S

(1)

Matsumura R

(1)

Oda T

(1)

Pascal JM

(1)

Sato M

(1)

Shinkai Y

(1)

Tomkinson AE

(1)

Tsusaka T

(1)

Homo / hetero assembly  (1)

hetero

(26)

Assembly composition  (3)

DNA/protein complex

(18)

DNA/DNA/RNA hybrid/protein complex

(6)

protein/protein complex

(2)

Assembly polymer count  (5)

tetramer

(21)

trimer

(2)

dimer

(1)

heptamer

(1)

octamer

(1)

Resolution distribution

1.5 - 2

(6)

2.0 - 2.5

(7)

2.5 - 3

(10)

4.0 - 4.5

(2)

4.5 - 5

(1)

Release year distribution

2000 - 2005

(1)

2015 - 2020

(8)

2020 - 2025

(17)

Journal  (5)

Nat Commun

(15)

J Biol Chem

(7)

Nucleic Acids Res

(2)

Nature

(1)

Structure

(1)

Organism superkingdom  (1)

Eukaryota

(25)

Organism name  (2)

Homo sapiens

(25)

synthetic construct

(1)

Molecule name  (3)

DNA ligase 1

(26)

DNA ligase I

(26)

Polydeoxyribonucleotide synthase [ATP] 1

(26)

Molecule type  (1)

Protein

(26)

Gene names  (1)

LIG1

(26)

Interacting Molecules  (36)

DNA (5'-D(P*GP*TP*CP*GP*GP*AP*C)-3')

(11)

DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*C)-3')

(8)

DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*GP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')

(8)

DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')

(4)

Proliferating cell nuclear antigen

(3)

DNA (5'-D(*GP*CP*AP*GP*AP*AP*TP*GP*GP*GP*CP*AP*GP*AP*CP*AP*TP*T)-3')

(2)

DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*G)-3')

(2)

DNA (5'-D(P*AP*TP*TP*CP*TP*GP*C)-3')

(2)

DNA chain 1

(2)

DNA chain 2

(2)

DNA chain 3

(2)

DNA/RNA (5'-R(P*G)-D(P*TP*CP*GP*GP*AP*C)-3')

(2)

Oligo13P

(2)

Oligo19ddC

(2)

Oligo32

(2)

5'-phosphorylated DNA

(1)

DNA (5'-D(*AP*AP*TP*GP*TP*CP*TP*GP*CP*CP*C)-3')

(1)

DNA (5'-D(*AP*AP*TP*GP*TP*CP*TP*GP*CP*CP*CP*C)-3')

(1)

DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*(8OG))-3')

(1)

DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*AP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')

(1)

DNA (5'-D(*GP*TP*CP*CP*GP*AP*CP*TP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')

(1)

DNA (5'-D(P*GP*TP*CP*CP*GP*AP*CP*CP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3')

(1)

DNA(5'-*GP*CP*TP*GP*AP*TP*GP*CP*GP*TP*A-3')

(1)

DNA(5'-*GP*TP*CP*CP*GP*AP*CP*TP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C-3')

(1)

DNA(5'-P*GP*TP*CP*GP*GP*AP*C-3')

(1)

DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*A)-3')

(1)

DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*A)-D(P*GP*TP*CP*GP*GP*AP*C)-3')

(1)

DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*G)-3')

(1)

DNA/RNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*T)-R(P*G)-D(P*GP*TP*CP*GP*GP*AP*C)-3')

(1)

Downstream Oligo

(1)

E3 ubiquitin-protein ligase UHRF1

(1)

Flap endonuclease 1

(1)

Template Oligo

(1)

Upstream Oligo

(1)

dideoxy terminated DNA

(1)

template DNA

(1)

Interacting ligands  (5)

AMP : ADENOSINE MONOPHOSPHATE

(22)

PEG : DI(HYDROXYETHYL)ETHER

(7)

MG : MAGNESIUM ION

(3)

ACT : ACETATE ION

(2)

PO4 : PHOSPHATE ION

(1)

EC number / name  (1)

6.5.1.1 : DNA ligase (ATP)

(26)

Biological function  (8)

DNA binding

(25)

DNA ligase (ATP) activity

(25)

ATP binding

(24)

DNA ligase activity

(24)

ligase activity

(1)

metal ion binding

(1)

nucleotide binding

(1)

protein binding

(1)

Biological process  (13)

DNA recombination

(25)

DNA repair

(25)

DNA biosynthetic process

(24)

DNA damage response

(1)

DNA replication

(1)

Okazaki fragment processing involved in mitotic DNA replication

(1)

V(D)J recombination

(1)

anatomical structure morphogenesis

(1)

base-excision repair

(1)

base-excision repair, gap-filling

(1)

cell division

(1)

lagging strand elongation

(1)

mismatch repair

(1)

Biological cell component  (3)

intracellular membrane-bounded organelle

(1)

nucleoplasm

(1)

nucleus

(1)

SCOP fold  (3)

ATP-dependent DNA ligase DNA-binding domain

(1)

ATP-grasp

(1)

OB-fold

(1)

SCOP family  (3)

ATP-dependent DNA ligase DNA-binding domain

(1)

ATP-dependent DNA ligase catalytic domain

(1)

DNA ligase/mRNA capping enzyme postcatalytic domain

(1)

CATH class  (3)

Alpha Beta

(1)

Mainly Alpha

(1)

Mainly Beta

(1)

CATH topology  (4)

D-amino Acid Aminotransferase; Chain A, domain 1

(1)

DNA ligase i, domain 1

(1)

Dna Ligase; domain 1

(1)

OB fold (Dihydrolipoamide Acetyltransferase, E2P)

(1)

Pfam accession / name  (3)

PF04675 : DNA_ligase_A_N

(25)

PF01068 : DNA_ligase_A_M

(24)

PF04679 : DNA_ligase_A_C

(24)

Diffraction protocol  (2)

Single wavelength

(22)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(23)

Diffraction source  (5)

APS BEAMLINE 22-ID

(17)

CHESS BEAMLINE 7B2

(4)

NSLS BEAMLINE X12C

(1)

NSLS BEAMLINE X25

(1)

PHOTON FACTORY BEAMLINE BL-17A

(1)

Synchrotron site  (4)

APS

(17)

CHESS

(4)

NSLS

(1)

Photon Factory

(1)

Diffraction detector type  (2)

Pixel

(22)

CCD

(1)

Refinement software  (2)

PHENIX

(23)

REFMAC

(2)

EM microscope model  (1)

FEI TITAN KRIOS

(3)

EM detector name  (1)

GATAN K3 BIOQUANTUM (6k x 4k)

(3)

Representative Structures

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