Entry status  (1)

REL

(25)

Experimental methods  (2)

Electron Microscopy

(18)

X-ray diffraction

(7)

Authors  (41)

Yin YW

(12)

Buchel G

(9)

Herbine K

(9)

Herbine KH

(9)

Nayak AR

(9)

Sarfallah A

(9)

Sokolova VO

(9)

Temiakov D

(9)

Zamudio-Ochoa A

(9)

Shumate CK

(7)

Herrmann GK

(6)

Park J

(6)

Szymanski MR

(5)

Borgnia MJ

(4)

Bouvette J

(4)

Brannon AJ

(4)

Copeland WC

(4)

Krahn JM

(4)

Mitchell PG

(4)

Riccio AA

(4)

Sherman MB

(4)

Williams JG

(4)

Amiralaei S

(3)

Anderson KS

(3)

Borgnia JM

(3)

Lee Y-S

(3)

Lee YS

(3)

Mislak AC

(3)

Schinazi RF

(3)

Sohl CD

(3)

Cisneros GA

(2)

Kuznestov VB

(2)

Kuznetsov VB

(2)

Meng Q

(2)

Patel G

(2)

Patel S

(2)

Patel SS

(2)

Roy A

(2)

Shumate C

(2)

Kennedy WD

(1)

Whitney YY

(1)

Homo / hetero assembly  (2)

hetero

(24)

homo

(1)

Assembly composition  (4)

DNA/protein complex

(19)

DNA/RNA/protein complex

(4)

protein structure

(1)

protein/protein complex

(1)

Assembly polymer count  (4)

pentamer

(22)

heptamer

(1)

monomer

(1)

trimer

(1)

Resolution distribution

2.0 - 2.5

(2)

2.5 - 3

(12)

3.0 - 3.5

(7)

3.5 - 4

(2)

4.0 - 4.5

(2)

Release year distribution

2005 - 2010

(1)

2010 - 2015

(2)

2015 - 2020

(5)

2020 - 2025

(19)

Journal  (7)

Nat Commun

(9)

Nat Struct Mol Biol

(4)

Nucleic Acids Res

(4)

Proc Natl Acad Sci U S A

(3)

EMBO J

(2)

Sci Adv

(2)

Cell

(1)

Organism superkingdom  (1)

Eukaryota

(25)

Organism name  (1)

Homo sapiens

(25)

Molecule name  (5)

3'-5' exodeoxyribonuclease

(25)

5'-deoxyribose-phosphate lyase

(25)

DNA polymerase subunit gamma-1

(25)

Mitochondrial DNA polymerase catalytic subunit

(25)

PolG-alpha

(25)

Molecule type  (1)

Protein

(25)

Gene names  (4)

MDP1

(25)

POLG

(25)

POLG1

(25)

POLGA

(25)

Interacting Molecules  (25)

DNA polymerase subunit gamma-2

(24)

Template DNA

(10)

DNA (25-MER)

(5)

Mismatched Primer DNA

(5)

DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*C)-3')

(3)

Mismatched RNA primer

(3)

DNA (26-MER)

(2)

DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3')

(2)

DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3')

(2)

DNA

(1)

DNA (24-MER)

(1)

DNA (28-MER)

(1)

DNA (44-MER)

(1)

DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3')

(1)

DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3')

(1)

DNA (5'-D(P*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*T)-3')

(1)

DNA (5'-D(P*AP*AP*GP*GP*GP*CP*CP*TP*AP*TP*AP*AP*AP*A)-3')

(1)

DNA (5'-D(P*AP*GP*GP*TP*AP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*T)-3')

(1)

DNA (5'-D(P*GP*GP*TP*AP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*T)-3')

(1)

DNA (5'-D(P*GP*GP*TP*AP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*T)-3')

(1)

DNA (5'-D(P*TP*TP*TP*TP*AP*TP*AP*GP*GP*CP*CP*CP*TP*T)-3')

(1)

DNA primer chain

(1)

DNA template chain

(1)

Mismatched RNA Primer

(1)

primer DNA

(1)

Interacting ligands  (8)

DCP : 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

(6)

MG : MAGNESIUM ION

(6)

CA : CALCIUM ION

(4)

1RY : [[(2R,5S)-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate

(2)

4Y3 : [[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3$l^{4}-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate

(1)

D3T : 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE

(1)

DCT : 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE

(1)

DOC : 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE

(1)

EC number / name  (1)

2.7.7.7 : DNA-directed DNA polymerase

(25)

Biological function  (13)

DNA binding

(25)

DNA-directed DNA polymerase activity

(25)

3'-5' exonuclease activity

(24)

5'-deoxyribose-5-phosphate lyase activity

(24)

DNA polymerase activity

(24)

chromatin binding

(24)

hydrolase activity

(24)

lyase activity

(24)

nucleotidyltransferase activity

(24)

protease binding

(24)

protein binding

(24)

single-stranded DNA 3'-5' DNA exonuclease activity

(24)

transferase activity

(24)

Biological process  (9)

DNA replication

(25)

mitochondrial DNA replication

(25)

DNA biosynthetic process

(24)

DNA metabolic process

(24)

DNA repair

(24)

DNA replication proofreading

(24)

DNA-templated DNA replication

(24)

base-excision repair

(24)

base-excision repair, gap-filling

(24)

Biological cell component  (7)

gamma DNA polymerase complex

(25)

intracellular membrane-bounded organelle

(24)

mitochondrial chromosome

(24)

mitochondrial matrix

(24)

mitochondrial nucleoid

(24)

mitochondrion

(24)

protein-containing complex

(24)

CATH class  (2)

Alpha Beta

(1)

Mainly Alpha

(1)

CATH topology  (2)

Nucleotidyltransferase; domain 5

(1)

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

(1)

Pfam accession / name  (1)

PF18136 : DNApol_Exo

(25)

Diffraction protocol  (1)

Single wavelength

(7)

Diffraction radiation source type  (1)

Synchrotron

(7)

Diffraction source  (2)

APS BEAMLINE 19-ID

(4)

ALS BEAMLINE 8.2.1

(3)

Synchrotron site  (2)

APS

(4)

ALS

(3)

Diffraction detector type  (1)

CCD

(7)

Refinement software  (2)

PHENIX

(10)

CNS

(1)

EM microscope model  (3)

FEI TITAN KRIOS

(14)

FEI TALOS ARCTICA

(2)

TFS KRIOS

(2)

EM detector name  (3)

GATAN K3 (6k x 4k)

(9)

GATAN K3 BIOQUANTUM (6k x 4k)

(7)

GATAN K2 SUMMIT (4k x 4k)

(2)

Representative Structures

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