Uniprot accession / id : P55041  OR   Uniprot accession / id : P55040
 
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Entry Information
Entry status  (1)
REL
(3)
 
Experimental methods  (1)
X-ray diffraction
(3)
 
Authors  (43)
Arrowsmith C
(1)
Berridge G
(1)
Bray J
(1)
Burgess N
(1)
Cabanie L
(1)
Cabanié L
(1)
Chomsky-Hecht O
(1)
Cicolari J
(1)
De Gunzburg J
(1)
Doyle D
(1)
Edwards A
(1)
El Marjou A
(1)
Elkins J
(1)
Fedorov O
(1)
Gileadi C
(1)
Hamoudi F
(1)
Hirsch JA
(1)
Houdusse A
(1)
Kelly K
(1)
Lee WH
(1)
Litvak Y
(1)
Menetrey J
(1)
Ménétrey J
(1)
Opatowsky Y
(1)
Pantic N
(1)
Perderiset M
(1)
Regazzoni K
(1)
Sasson Y
(1)
Schoch G
(1)
Selinger Z
(1)
Shaked I
(1)
Sobott F
(1)
Soundararajan M
(1)
Splingard A
(1)
Structural Genomics Consortium (SGC)
(1)
Sundstrom M
(1)
Turnbull A
(1)
Ugochukwu E
(1)
Ward Y
(1)
Weigelt J
(1)
Wells A
(1)
de Gunzburg J
(1)
von Delft F
(1)
 
Homo / hetero assembly  (2)
homo
(2)
hetero
(1)
 
Assembly composition  (2)
protein structure
(2)
protein/protein complex
(1)
 
Assembly polymer count  (2)
monomer
(2)
dimer
(1)
 
Resolution distribution
2.0 - 2.5
(3)
 
Release year distribution
2005 - 2010
(3)
 
Journal  (3)
FEBS Lett
(1)
J Biol Chem
(1)
To be published
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(3)
 
Organism name  (1)
Homo sapiens
(3)
 
Molecule name  (3)
GTP-binding mitogen-induced T-cell protein
(3)
GTP-binding protein GEM
(3)
RAS-like protein KIR
(3)
 
Molecule type  (1)
Protein
(3)
 
Gene names  (2)
GEM
(3)
KIR
(3)
 
Interacting Molecules  (1)
GTP-binding protein GEM
(1)
 
Interacting ligands  (2)
GDP : GUANOSINE-5'-DIPHOSPHATE
(3)
MG : MAGNESIUM ION
(2)
 
Function and Biology
Biological function  (2)
GTP binding
(3)
GTPase activity
(3)
 
Sequence and Structure classification
SCOP fold  (1)
P-loop containing nucleoside triphosphate hydrolases
(1)
 
SCOP family  (1)
G proteins
(1)
 
CATH class  (1)
Alpha Beta
(3)
 
CATH topology  (1)
Rossmann fold
(3)
 
Pfam accession / name  (1)
PF00071 : Ras
(3)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(3)
 
Diffraction radiation source type  (1)
Synchrotron
(3)
 
Diffraction source  (3)
ALS BEAMLINE 8.2.1
(1)
ESRF BEAMLINE ID14-1
(1)
ESRF BEAMLINE ID14-4
(1)
 
Synchrotron site  (2)
ESRF
(2)
ALS
(1)
 
Diffraction detector type  (1)
CCD
(3)
 
Refinement software  (1)
REFMAC
(3)
 
Representative Structures
Representative Structures
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Entries 1 to 3 of 3
Entries 1 to 3 of 3
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Crystal structure of the human small GTPase GEM
Ugochukwu E, Soundararajan M, Elkins J, Gileadi C, Schoch G, Sobott F, Fedorov O, Bray J, Pantic N, Berridge G, Burgess N, Lee WH, Turnbull A, Sundstrom M, Arrowsmith C, Weigelt J, Edwards A, von Delft F, Doyle D, Structural Genomics Consortium (SGC)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: GDP    GDP   
Assembly name: GTP-binding protein GEM (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157156 (Preferred)   search this ID
PDBe-KB: P55040   
X-ray diffraction
2.4Å resolution
Released: 18 Apr 2006
Model geometry
Fit model/data
2g3y
2g3y
2g3y
Crystal structure of the small GTPase Gem (GemDNDCaM) in complex to Mg.GDP
Splingard A, Menetrey J, Perderiset M, Cicolari J, Hamoudi F, Cabanie L, El Marjou A, Wells A, Houdusse A, de Gunzburg J
J Biol Chem (2007) [PMID: 17107948  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: GDP    MG    GDP    MG   
Modified residues: CAS    CAS   
Assembly name: GTP-binding protein GEM (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157157 (Preferred)   search this ID
PDBe-KB: P55040   
X-ray diffraction
2.1Å resolution
Released: 9 Nov 2006
Model geometry
Fit model/data
2cjw
2cjw
2cjw
Crystal structure of Human Gem G-domain bound to GDP
Opatowsky Y, Hirsch JA
FEBS Lett (2006) [PMID: 17052716  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: GDP    MG    GDP    MG   
Assembly name: GTP-binding protein GEM (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157156 (Preferred)   search this ID
PDBe-KB: P55040   
X-ray diffraction
2.4Å resolution
Released: 31 Oct 2006
Model geometry
Fit model/data
2ht6
2ht6
2ht6
Entries 1 to 3 of 3
Entries 1 to 3 of 3