Uniprot accession / id : (P62140)
 
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Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (5)
Dominguez R
(1)
Kerff F
(1)
Langsetmo K
(1)
Tao T
(1)
Terrak M
(1)
 
Homo / hetero assembly  (1)
hetero
(1)
 
Assembly composition  (1)
protein/protein complex
(1)
 
Assembly polymer count  (1)
dimer
(1)
 
Resolution distribution
2.5 - 3
(1)
 
Release year distribution
2000 - 2005
(1)
 
Journal  (1)
Nature
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (2)
PP-1B
(1)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (1)
PPP1CB
(1)
 
Interacting Molecules  (1)
Protein phosphatase 1 regulatory subunit 12A
(1)
 
Interacting ligands  (2)
MN : MANGANESE (II) ION
(1)
PGE : TRIETHYLENE GLYCOL
(1)
 
Function and Biology
EC number / name  (2)
3.1.3.16 : Protein-serine/threonine phosphatase
(1)
3.1.3.53 : [Myosin-light-chain] phosphatase
(1)
 
Biological function  (14)
MAP kinase serine/threonine phosphatase activity
(1)
RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity
(1)
RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity
(1)
RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity
(1)
RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity
(1)
RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity
(1)
calmodulin-dependent protein phosphatase activity
(1)
histone H2AXS140 phosphatase activity
(1)
hydrolase activity
(1)
metal ion binding
(1)
myosin phosphatase activity
(1)
myosin-light-chain-phosphatase activity
(1)
phosphoprotein phosphatase activity
(1)
protein serine/threonine phosphatase activity
(1)
 
Biological process  (7)
cell division
(1)
chromatin remodeling
(1)
circadian regulation of gene expression
(1)
glycogen metabolic process
(1)
regulation of cell adhesion
(1)
regulation of circadian rhythm
(1)
regulation of transcription by RNA polymerase II
(1)
 
Biological cell component  (3)
PTW/PP1 phosphatase complex
(1)
cytoplasm
(1)
nucleus
(1)
 
Representative Structures
Representative Structures
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Complex between protein ser/thr phosphatase-1 (delta) and the myosin phosphatase targeting subunit 1 (MYPT1)
Kerff F, Terrak M, Dominguez R
Nature (2004) [PMID: 15164081  ]
Assembly composition: protein/protein complex
Bound ligands: MN    MN    PGE    PGE   
Assembly name: Serine/threonine-protein phosphatase PP1-beta catalytic subunit and Protein phosphatase 1 regulatory subunit 12A (Preferred)   search this complex
PDBe complex ID: PDB-CPX-158592 (Preferred)   search this ID
PDBe-KB: P62207    Q90623   
X-ray diffraction
2.7Å resolution
Released: 22 Jun 2004
Model geometry
Fit model/data
Data not deposited
1s70
1s70
1s70
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