Uniprot accession / id : P62264  OR   Uniprot accession / id : P62263
 
Filter by :
Entry Information
Entry status  (1)
REL
(132)
 
Experimental methods  (2)
Electron Microscopy
(131)
X-ray diffraction
(1)
 
Authors  (390)
Beckmann R
(46)
Cheng J
(45)
Berninghausen O
(35)
Ameismeier M
(30)
Thoms M
(23)
Buschauer R
(18)
Denk T
(16)
Kratzat H
(14)
Li Y
(14)
Becker T
(13)
Mackens-Kiani T
(13)
Wang M
(12)
Natchiar SK
(11)
Fischer N
(9)
Frohlich T
(9)
Fröhlich T
(9)
Hayn M
(9)
Hirschenberger M
(9)
Kirchhoff F
(9)
Koepke L
(9)
Petrychenko V
(9)
Rodnina MV
(9)
Sparrer KMJ
(9)
Straub JH
(9)
Sturzel CM
(9)
Stürzel CM
(9)
Yi S-H
(9)
Yi SH
(9)
Yokoyama T
(9)
Cate JHD
(8)
Chang ST
(8)
Huang Z
(8)
Hurt E
(8)
Lau B
(8)
Li W
(8)
Li X
(8)
Montabana E
(8)
Myasnikov AG
(8)
Ward FR
(8)
Wei Z
(8)
Yong X
(8)
Dullea RG
(7)
Fraser CS
(7)
Klaholz BP
(7)
Kutay U
(7)
Liedtke D
(7)
Liras S
(7)
McClure KF
(7)
Peng BZ
(7)
Shirouzu M
(7)
Sokabe M
(7)
Ban N
(6)
Brito Querido J
(6)
Gordiyenko Y
(6)
Green R
(6)
Leibundgut M
(6)
Ramakrishnan V
(6)
van den Heuvel J
(6)
Altman RB
(5)
Blanchard SC
(5)
Holm M
(5)
Natchiar KS
(5)
Rundlet EJ
(5)
Taunton J
(5)
Wang HY
(5)
Watson ZL
(5)
Ye X
(5)
Zemp I
(5)
Akichika S
(4)
Best K
(4)
Fraser C
(4)
Irie T
(4)
Ishibashi K
(4)
Ishiguro K
(4)
Iwasaki S
(4)
Karousis ED
(4)
Ma D
(4)
Matsuzawa I
(4)
Mishima Y
(4)
Mito M
(4)
Muehlemann O
(4)
Muhlemann O
(4)
Mühlemann O
(4)
Saito H
(4)
Sakaguchi Y
(4)
Scaiola A
(4)
Schubert K
(4)
Suzuki T
(4)
Wakabayashi K
(4)
Zhao X
(4)
von Loeffelholz O
(4)
Artus-Revel CG
(3)
Bhaskar V
(3)
Bretones G
(3)
Cavadini S
(3)
Chaker-Margot M
(3)
Chao JA
(3)
Chen FX
(3)
Diaz-Lopez I
(3)
Diehl FF
(3)
 
More...
 
Homo / hetero assembly  (1)
hetero
(132)
 
Assembly composition  (2)
RNA/protein complex
(131)
protein/protein complex
(1)
 
Assembly polymer count  (36)
37-mer
(12)
83-mer
(11)
36-mer
(10)
35-mer
(9)
86-mer
(9)
80-mer
(8)
85-mer
(8)
81-mer
(7)
38-mer
(6)
84-mer
(6)
50-mer
(4)
54-mer
(4)
34-mer
(3)
51-mer
(3)
79-mer
(3)
82-mer
(3)
33-mer
(2)
53-mer
(2)
57-mer
(2)
78-mer
(2)
88-mer
(2)
nonadecamer
(2)
171-mer
(1)
172-mer
(1)
22-mer
(1)
23-mer
(1)
26-mer
(1)
31-mer
(1)
48-mer
(1)
49-mer
(1)
52-mer
(1)
72-mer
(1)
74-mer
(1)
75-mer
(1)
89-mer
(1)
92-mer
(1)
 
Resolution distribution
1.5 - 2
(4)
2.0 - 2.5
(9)
2.5 - 3
(44)
3.0 - 3.5
(41)
3.5 - 4
(25)
4.0 - 4.5
(5)
4.5 - 5
(2)
5.5 - 6
(1)
6.0 - 6.5
(1)
 
Release year distribution
2010 - 2015
(5)
2015 - 2020
(56)
2020 - 2025
(104)
2025 - 2030
(10)
 
Journal  (17)
Nature
(25)
Nat Struct Mol Biol
(18)
Science
(16)
Nat Commun
(14)
Nucleic Acids Res
(12)
Mol Cell
(9)
To be published
(8)
Cell
(5)
Cell Rep
(5)
EMBO J
(4)
Cell Res
(3)
Elife
(3)
PLoS Biol
(3)
Cancer Discov
(2)
Front Mol Biosci
(2)
J Biochem
(2)
bioRxiv
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(132)
 
Organism name  (3)
Homo sapiens
(127)
Mus musculus
(4)
Oryctolagus cuniculus
(1)
 
Molecule name  (2)
40S ribosomal protein S14
(132)
Small ribosomal subunit protein uS11
(132)
 
Molecule type  (1)
Protein
(132)
 
Gene names  (3)
PRO2640
(128)
RPS14
(128)
Rps14
(4)
 
Interacting Molecules  (316)
Small ribosomal subunit protein eS1
(132)
Small ribosomal subunit protein uS15
(132)
Small ribosomal subunit protein eS7
(131)
Small ribosomal subunit protein eS27
(130)
Small ribosomal subunit protein eS6
(130)
Small ribosomal subunit protein eS8
(130)
Small ribosomal subunit protein uS17
(130)
Small ribosomal subunit protein uS4
(130)
Small ribosomal subunit protein uS8
(130)
Small ribosomal subunit protein eS24
(129)
Small ribosomal subunit protein eS28
(128)
Small ribosomal subunit protein uS7
(127)
Small ribosomal subunit protein uS9
(127)
Small ribosomal subunit protein eS17
(126)
Small ribosomal subunit protein uS12
(125)
Small ribosomal subunit protein uS2
(125)
Small ribosomal subunit protein eS19
(124)
Small ribosomal subunit protein eS25
(124)
Small ribosomal subunit protein uS13
(124)
Small ribosomal subunit protein uS19
(124)
Small ribosomal subunit protein eS21
(123)
Small ribosomal subunit protein uS5
(123)
Small ribosomal subunit protein eS4, X isoform
(121)
Small ribosomal subunit protein RACK1
(115)
Small ribosomal subunit protein eS12
(115)
18S Ribosomal RNA
(114)
Small ribosomal subunit protein eS10
(114)
Small ribosomal subunit protein uS10
(114)
Small ribosomal subunit protein uS14
(114)
Small ribosomal subunit protein uS3
(114)
Small ribosomal subunit protein eS26
(107)
Small ribosomal subunit protein eS30
(106)
Small ribosomal subunit protein eS32
(98)
Ubiquitin-ribosomal protein eS31 fusion protein
(88)
Large ribosomal subunit protein eL19
(64)
Large ribosomal subunit protein eL24
(64)
Large ribosomal subunit protein eL14
(63)
Large ribosomal subunit protein eL15
(63)
Large ribosomal subunit protein eL18
(63)
Large ribosomal subunit protein eL20
(63)
Large ribosomal subunit protein eL21
(63)
Large ribosomal subunit protein eL22
(63)
Large ribosomal subunit protein eL28
(63)
Large ribosomal subunit protein eL30
(63)
Large ribosomal subunit protein eL31
(63)
Large ribosomal subunit protein eL32
(63)
Large ribosomal subunit protein eL33
(63)
Large ribosomal subunit protein eL34
(63)
Large ribosomal subunit protein eL36
(63)
Large ribosomal subunit protein eL37
(63)
Large ribosomal subunit protein eL38
(63)
Large ribosomal subunit protein eL43
(63)
Large ribosomal subunit protein eL6
(63)
Large ribosomal subunit protein eL8
(63)
Large ribosomal subunit protein uL13
(63)
Large ribosomal subunit protein uL14
(63)
Large ribosomal subunit protein uL18
(63)
Large ribosomal subunit protein uL22
(63)
Large ribosomal subunit protein uL23
(63)
Large ribosomal subunit protein uL24
(63)
Large ribosomal subunit protein uL29
(63)
Large ribosomal subunit protein uL3
(63)
Large ribosomal subunit protein uL30
(63)
Large ribosomal subunit protein uL4
(63)
Large ribosomal subunit protein uL5
(63)
Large ribosomal subunit protein uL6
(63)
Large ribosomal subunit protein eL13
(62)
Large ribosomal subunit protein eL29
(62)
Large ribosomal subunit protein eL39
(62)
Large ribosomal subunit protein uL15
(62)
Large ribosomal subunit protein eL27
(61)
Large ribosomal subunit protein uL2
(58)
28S ribosomal RNA
(56)
5.8S ribosomal RNA
(55)
5S ribosomal RNA
(55)
Large ribosomal subunit protein eL42
(55)
Ubiquitin-ribosomal protein eL40 fusion protein
(39)
Messenger RNA
(38)
Ribosomal protein uL16-like
(38)
Large ribosomal subunit protein uL1
(36)
Large ribosomal subunit protein uL10
(25)
Small ribosomal subunit protein eS31
(24)
RNA-binding protein PNO1
(22)
tRNA
(22)
Eukaryotic translation initiation factor 3 subunit C
(20)
Large ribosomal subunit protein uL16
(20)
Eukaryotic translation initiation factor 3 subunit A
(19)
Eukaryotic translation initiation factor 3 subunit E
(19)
Eukaryotic translation initiation factor 3 subunit L
(19)
Eukaryotic translation initiation factor 3 subunit M
(19)
Large ribosomal subunit protein uL11
(19)
Eukaryotic translation initiation factor 3 subunit D
(18)
Eukaryotic translation initiation factor 3 subunit F
(18)
Eukaryotic translation initiation factor 3 subunit H
(18)
Eukaryotic translation initiation factor 3 subunit K
(18)
Large ribosomal subunit protein eL40
(18)
Pre-rRNA-processing protein TSR1 homolog
(17)
Elongation factor 2
(16)
Eukaryotic translation initiation factor 3 subunit B
(16)
Proliferation-associated protein 2G4
(16)
 
More...
 
Interacting ligands  (2)
MG : MAGNESIUM ION
(42)
K : POTASSIUM ION
(7)
 
Function and Biology
Biological function  (5)
structural constituent of ribosome
(125)
RNA binding
(122)
mRNA 5'-UTR binding
(122)
translation regulator activity
(122)
protein binding
(118)
 
Biological process  (10)
translation
(125)
cytoplasmic translation
(122)
erythrocyte differentiation
(122)
maturation of SSU-rRNA
(122)
negative regulation of transcription by RNA polymerase II
(122)
regulation of translation
(122)
ribosomal small subunit assembly
(122)
ribosomal small subunit biogenesis
(122)
translation at postsynapse
(4)
translation at presynapse
(4)
 
Biological cell component  (19)
ribosome
(125)
cytoplasm
(122)
cytosol
(122)
cytosolic ribosome
(122)
cytosolic small ribosomal subunit
(122)
nucleolus
(122)
nucleus
(122)
postsynaptic density
(122)
ribonucleoprotein complex
(122)
small ribosomal subunit
(122)
small-subunit processome
(122)
synapse
(122)
extracellular exosome
(118)
focal adhesion
(118)
membrane
(118)
nucleoplasm
(118)
mitochondrion
(4)
postsynapse
(4)
presynapse
(4)
 
Sequence and Structure classification
CATH class  (1)
Alpha Beta
(6)
 
CATH topology  (1)
Nucleotidyltransferase; domain 5
(6)
 
Pfam accession / name  (1)
PF00411 : Ribosomal_S11
(132)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(2)
 
Diffraction radiation source type  (1)
Synchrotron
(1)
 
Diffraction source  (1)
APS BEAMLINE 24-ID-C
(1)
 
Synchrotron site  (1)
APS
(1)
 
Diffraction detector type  (1)
Pixel
(1)
 
Refinement software  (3)
PHENIX
(27)
phenix.real_space_refine
(16)
REFMAC
(2)
 
EM microscope model  (4)
FEI TITAN KRIOS
(124)
FEI TECNAI ARCTICA
(3)
JEOL CRYO ARM 300
(3)
TFS KRIOS
(2)
 
EM detector name  (10)
GATAN K2 SUMMIT (4k x 4k)
(46)
GATAN K3 (6k x 4k)
(40)
FEI FALCON II (4k x 4k)
(15)
FEI FALCON III (4k x 4k)
(15)
FEI FALCON IV (4k x 4k)
(8)
GATAN K3 BIOQUANTUM (6k x 4k)
(4)
FEI EAGLE (4k x 4k)
(1)
GATAN K2 QUANTUM (4k x 4k)
(1)
GATAN K3 BIOCONTINUUM (6k x 4k)
(1)
TVIPS TEMCAM-F416 (4k x 4k)
(1)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
...
Entries 1 to 10 of 132
Entries 1 to 10 of 132
 Select all entries on this page
Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline
Li X, Wang M, Denk T, Cheng J
Nat Commun (2024) [PMID: 38942792  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
PDBe complex ID: PDB-CPX-272331 (Preferred)   search this ID
PDBe-KB: P62263    P32969    P40429    P46779    P62753    P62081    (view 72 more)
Electron Microscopy
2.2Å resolution
Released: 10 Jul 2024
Model geometry
Fit model/data
Data not analysed
8yop
8yop
8yop
In situ human top-back di-ribosome structure (Composite map)
Wei Z, Yong Z
To be published
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
Modified residues: N    N   
PDBe complex ID: PDB-CPX-290437 (Preferred)   search this ID
PDBe-KB: P62263    P32969    P40429    P46779    P62753    P62081    (view 73 more)
Electron Microscopy
3.2Å resolution
Released: 19 Mar 2025
Model geometry
Fit model/data
Data not analysed
9b0q
9b0q
9b0q
SARS-COV-2 nsp1 in complex with human 40S ribosome
Wang L, Shi M, Wu H
bioRxiv (2020) [PMID: 32995777  ]
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
Assembly name: SARS-CoV-2 NSP10-NSP16 2'-O-methyltransferase complex and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-276038 (Preferred)   search this ID
PDBe-KB: P62263    P62753    P62081    P60866    P62979    P46781    (view 29 more)
Electron Microscopy
2.9Å resolution
Released: 14 Oct 2020
Model geometry
Fit model/data
Data not analysed
7k5i
7k5i
7k5i
dormant ribosome with eIF5A, eEF2 and SERBP1
Du M, Zeng F
Front Mol Biosci (2024) [PMID: 38698775  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
PDBe complex ID: PDB-CPX-272439 (Preferred)   search this ID
PDBe-KB: P62263    P32969    P40429    P46779    P62753    P62081    (view 71 more)
Electron Microscopy
3.4Å resolution
Released: 7 Feb 2024
Model geometry
Fit model/data
Data not analysed
8y0w
8y0w
8y0w
MERS-CoV Nsp1 protein bound to the Human 40S Ribosomal subunit
Devarkar SC, Xiong Y
Cell Rep (2023) [PMID: 37733586  ]
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
Assembly name: MERS-CoV 3'-5' exoribonuclease proof-reading complex and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-271381 (Preferred)   search this ID
PDBe-KB: P62263    P62753    P62081    P60866    P62979    P46781    (view 29 more)
Electron Microscopy
2.6Å resolution
Released: 4 Oct 2023
Model geometry
Fit model/data
Data not analysed
8t4s
8t4s
8t4s
Structure of human eIF3 core from closed 48S translation initiation complex
Petrychenko V, Yi S-H, Liedtke D, Peng BZ, Rodnina MV, Fischer N
Nat Struct Mol Biol (2024) [PMID: 39289545  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
Modified residues: A2M    B8N    OMC    OMG    5MC    6MZ    OMU    5MC    UR3    5MU    5MU    6MZ    A2M    MA6    PSU    PSU    JMH    MA6    OMC    OMG    OMU    UR3   
PDBe complex ID: PDB-CPX-271450 (Preferred)   search this ID
PDBe-KB: P62263    Q7L2H7    Q14152    O00303    Q9Y262    O15371    (view 11 more)
Electron Microscopy
3.4Å resolution
Released: 14 Aug 2024
Model geometry
Fit model/data
Data not analysed
8rg0
8rg0
8rg0
In situ human hibernating class2 80S ribosome
Wei Z, Yong X
To be published
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
PDBe complex ID: PDB-CPX-290432 (Preferred)   search this ID
PDBe-KB: P62263    P32969    P40429    P46779    P62753    P62081    (view 73 more)
Electron Microscopy
2.81Å resolution
Released: 19 Mar 2025
Model geometry
Fit model/data
Data not analysed
9b0r
9b0r
9b0r
Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G
Ye X, Huang Z, Li Y, Wang M, Cheng J
Cell Res (2024) [PMID: 38641729  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
PDBe complex ID: PDB-CPX-271866 (Preferred)   search this ID
PDBe-KB: P62263    P62753    P62081    P60866    P62979    Q53EL6    (view 30 more)
Electron Microscopy
3.2Å resolution
Released: 1 May 2024
Model geometry
Fit model/data
Data not analysed
8xxm
8xxm
8xxm
Cryo-EM structure of the human 40S ribosome with PDCD4
Ye X, Huang Z, Li Y, Wang M, Cheng J
Cell Res (2024) [PMID: 38641729  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: MG    ZN    ZN    MG   
PDBe complex ID: PDB-CPX-272448 (Preferred)   search this ID
PDBe-KB: P62263    P62753    P62081    P60866    P62979    Q53EL6    (view 29 more)
Electron Microscopy
2.9Å resolution
Released: 1 May 2024
Model geometry
Fit model/data
Data not analysed
8xxl
8xxl
8xxl
Arbekacin-added human 80S ribosome
Tomono J, Asano K, Chiashi T, Tanaka Y, Yokoyama T
J Biochem (2024) [PMID: 38227611  ]
Source organism: Homo sapiens  
Assembly composition: RNA/protein complex
Bound ligands: 84G    MG    ZN    84G    ZN    MG   
Modified residues: MLZ    MLZ   
PDBe complex ID: PDB-CPX-272442 (Preferred)   search this ID
PDBe-KB: P62263    P60866    P32969    P40429    P46779    P62081    (view 70 more)
Electron Microscopy
2.57Å resolution
Released: 14 Feb 2024
Model geometry
Fit model/data
Data not analysed
8ife
8ife
8ife
...
Entries 1 to 10 of 132
Entries 1 to 10 of 132