Entry status  (1)

REL

(22)

Experimental methods  (3)

X-ray diffraction

(18)

Electron Microscopy

(3)

Solution NMR

(1)

Authors  (60)

Dominguez R

(7)

Almo SC

(5)

Mechold U

(5)

Rebowski G

(5)

Comisso M

(4)

Fedorov AA

(4)

Ladant D

(4)

Missinou AA

(4)

Plancqueel S

(4)

Raoux-Barbot D

(4)

Renault L

(4)

Retailleau P

(4)

Teixeira-Nunes M

(4)

Velours C

(4)

Arnesen T

(3)

Boczkowska M

(3)

Boopathy S

(3)

Bosco DA

(3)

Drazic A

(3)

Ferron F

(3)

Goode BL

(3)

Goris M

(3)

Jansen S

(3)

Landers JE

(3)

Mahoney NM

(3)

Ree R

(3)

Schiffer CA

(3)

Shandilya SM

(3)

Shandilya SMD

(3)

Silvas TV

(3)

Tischbein M

(3)

Zitzewitz JA

(3)

Fedorov E

(2)

Lee SH

(2)

Pollard TD

(2)

Raunser S

(2)

Rozwarski DA

(2)

Baek K

(1)

Barrie KR

(1)

Belyy A

(1)

Bieling P

(1)

Boiero Sanders M

(1)

Constantine KL

(1)

Farmer 2nd BT

(1)

Farmer BT

(1)

Farmer II BT

(1)

Friedrichs MS

(1)

Funk J

(1)

Janmey PA

(1)

Korn ED

(1)

Lavoie T

(1)

Liu X

(1)

Merino F

(1)

Metzler WJ

(1)

Mueller L

(1)

Oosterheert W

(1)

Palmer NJ

(1)

Prumbaum D

(1)

Shu S

(1)

Texeira-Nuns M

(1)

Homo / hetero assembly  (2)

hetero

(16)

homo

(6)

Assembly composition  (2)

protein/protein complex

(16)

protein structure

(6)

Assembly polymer count  (5)

trimer

(9)

monomer

(6)

dimer

(4)

decamer

(2)

tetramer

(1)

Resolution distribution

1.5 - 2

(7)

2.0 - 2.5

(10)

2.5 - 3

(1)

3.5 - 4

(2)

6.0 - 6.5

(1)

Release year distribution

1990 - 1995

(1)

1995 - 2000

(6)

2005 - 2010

(3)

2010 - 2015

(3)

2015 - 2020

(6)

2020 - 2025

(10)

Journal  (10)

PLoS Pathog

(4)

Proc Natl Acad Sci U S A

(4)

Nat Struct Biol

(3)

Sci Adv

(3)

EMBO J

(2)

To be published

(2)

Nat Commun

(1)

Nature

(1)

Protein Sci

(1)

Science

(1)

Organism superkingdom  (2)

Eukaryota

(21)

Bacteria

(3)

Organism name  (3)

Homo sapiens

(21)

Vibrio nigripulchritudo

(2)

Vibrio nigripulchritudo SFn135

(1)

Molecule name  (5)

Epididymis tissue protein Li 184a

(22)

Profilin I

(22)

Profilin-1

(22)

MARTX

(3)

Peptidase C80 domain-containing protein

(3)

Molecule type  (1)

Protein

(22)

Gene names  (2)

PFN1

(22)

VIBNI_0210

(3)

Interacting Molecules  (15)

Actin, alpha skeletal muscle

(9)

Actin, cytoplasmic 1

(3)

N-alpha-acetyltransferase 80

(3)

Vasodilator-stimulated phosphoprotein

(3)

Cell division control protein 12

(1)

Inverted formin-2

(1)

L-PRO10

(1)

MARTX

(1)

Major actin

(1)

Maltose/maltodextrin-binding periplasmic protein

(1)

Methylated-DNA--protein-cysteine methyltransferase

(1)

PROTEIN (L-PRO10-IODOTYROSINE)

(1)

PROTEIN (PROLINE PEPTIDE)

(1)

Peptidase C80 domain-containing protein

(1)

Phalloidin (Amanita phalloides)

(1)

Interacting ligands  (10)

PEO : HYDROGEN PEROXIDE

(3)

SO4 : SULFATE ION

(3)

GOL : GLYCEROL

(2)

LAB : LATRUNCULIN B

(2)

PEG : DI(HYDROXYETHYL)ETHER

(2)

PO4 : PHOSPHATE ION

(2)

TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL

(2)

CH1 : 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE

(1)

HOM : 7-HYDROXY-4-METHYL-3-(2-HYDROXY-ETHYL)COUMARIN

(1)

MN : MANGANESE (II) ION

(1)

EC number / name  (1)

4.6.1.1 : Adenylate cyclase

(3)

Biological function  (11)

RNA binding

(22)

actin binding

(22)

actin monomer binding

(22)

adenyl-nucleotide exchange factor activity

(22)

cadherin binding

(22)

phosphatidylinositol-4,5-bisphosphate binding

(22)

phosphotyrosine residue binding

(22)

proline-rich region binding

(22)

protein binding

(22)

small GTPase binding

(22)

calcium- and calmodulin-responsive adenylate cyclase activity

(3)

Biological process  (17)

actin cytoskeleton organization

(22)

modification of postsynaptic actin cytoskeleton

(22)

modulation of chemical synaptic transmission

(22)

negative regulation of actin filament bundle assembly

(22)

negative regulation of actin filament polymerization

(22)

negative regulation of stress fiber assembly

(22)

neural tube closure

(22)

positive regulation of ATP-dependent activity

(22)

positive regulation of actin filament bundle assembly

(22)

positive regulation of actin filament polymerization

(22)

positive regulation of epithelial cell migration

(22)

positive regulation of ruffle assembly

(22)

protein stabilization

(22)

regulation of actin filament organization

(22)

regulation of actin filament polymerization

(22)

regulation of transcription by RNA polymerase II

(22)

synapse maturation

(22)

Biological cell component  (11)

blood microparticle

(22)

cell cortex

(22)

cytoplasm

(22)

cytoskeleton

(22)

cytosol

(22)

extracellular exosome

(22)

focal adhesion

(22)

glutamatergic synapse

(22)

membrane

(22)

nucleus

(22)

extracellular region

(3)

SCOP fold  (1)

Profilin-like

(9)

SCOP family  (1)

Profilin (actin-binding protein)

(9)

CATH class  (1)

Alpha Beta

(12)

CATH topology  (1)

Beta-Lactamase

(12)

Pfam accession / name  (2)

PF00235 : Profilin

(22)

PF03497 : Anthrax_toxA

(3)

Diffraction protocol  (1)

Single wavelength

(15)

Diffraction radiation source type  (2)

Synchrotron

(10)

Rotating anode

(8)

Diffraction source  (8)

CHESS BEAMLINE F1

(3)

RIGAKU MICROMAX-007 HF

(3)

RIGAKU RUH2R

(3)

SOLEIL BEAMLINE PROXIMA 1

(3)

APS BEAMLINE 14-BM-C

(2)

RIGAKU RU200

(2)

CHESS BEAMLINE F2

(1)

SOLEIL BEAMLINE PROXIMA 2

(1)

Synchrotron site  (3)

CHESS

(4)

SOLEIL

(4)

APS

(2)

Diffraction detector type  (3)

Pixel

(7)

CCD

(6)

Area detector

(5)

Refinement software  (5)

PHENIX

(7)

X-PLOR

(6)

BUSTER

(4)

REFMAC

(3)

PROFFT

(2)

EM microscope model  (1)

FEI TITAN KRIOS

(3)

EM detector name  (2)

GATAN K3 (6k x 4k)

(2)

GATAN K3 BIOQUANTUM (6k x 4k)

(1)

NMR software packages  (1)

X-PLOR

(1)

Representative Structures

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