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Entry Information
Entry status
(1)
Experimental methods
(3)
Solution NMR
(2)
X-ray diffraction
(2)
Electron Microscopy
(1)
Authors
(37)
Aichem A
(2)
Anders S
(2)
Berg A
(2)
Bialas J
(2)
Catone N
(2)
Groettrup M
(2)
Peter C
(2)
Roessler P
(2)
Rößler P
(2)
Scheuermann S
(2)
Schmidtke G
(2)
Schutz-Stoffregen MC
(2)
Schwab R
(2)
Schütz-Stoffregen MC
(2)
Stotz S
(2)
Wiesner S
(2)
Arkinson C
(1)
Chan C
(1)
Chong SS
(1)
Dong KC
(1)
Gao Y
(1)
Gee CL
(1)
Kuhn M
(1)
Lee CG
(1)
Li S
(1)
Lim L
(1)
Mah WC
(1)
Martin A
(1)
Misra M
(1)
Qin H
(1)
Schindelin H
(1)
Song J
(1)
Theng SS
(1)
Truongvan N
(1)
Wang W
(1)
Zhang Z
(1)
Zhuo J
(1)
Homo / hetero assembly
(2)
homo
(3)
hetero
(2)
Assembly composition
(2)
protein structure
(3)
protein/protein complex
(2)
Assembly polymer count
(3)
monomer
(3)
34-mer
(1)
dimer
(1)
Resolution distribution
1.5 - 2
(1)
3.0 - 3.5
(2)
Release year distribution
2010 - 2015
(1)
2015 - 2020
(2)
2020 - 2025
(2)
Journal
(3)
Nat Commun
(3)
Proc Natl Acad Sci U S A
(1)
bioRxiv
(1)
Macromolecules
Organism superkingdom
(1)
Eukaryota
(5)
Organism name
(2)
Homo sapiens
(5)
Lobophyllia hemprichii
(1)
Molecule name
(4)
Diubiquitin
(5)
Ubiquitin D
(5)
Ubiquitin-like protein FAT10
(5)
Green to red photoconvertible GFP-like protein EosFP
(1)
Molecule type
(1)
Protein
(5)
Gene names
(2)
FAT10
(5)
UBD
(5)
Interacting Molecules
(35)
26S proteasome complex subunit SEM1
(1)
26S proteasome non-ATPase regulatory subunit 1
(1)
26S proteasome non-ATPase regulatory subunit 11
(1)
26S proteasome non-ATPase regulatory subunit 12
(1)
26S proteasome non-ATPase regulatory subunit 13
(1)
26S proteasome non-ATPase regulatory subunit 14
(1)
26S proteasome non-ATPase regulatory subunit 2
(1)
26S proteasome non-ATPase regulatory subunit 3
(1)
26S proteasome non-ATPase regulatory subunit 4
(1)
26S proteasome non-ATPase regulatory subunit 6
(1)
26S proteasome non-ATPase regulatory subunit 7
(1)
26S proteasome non-ATPase regulatory subunit 8
(1)
26S proteasome regulatory subunit 10B
(1)
26S proteasome regulatory subunit 4
(1)
26S proteasome regulatory subunit 6A
(1)
26S proteasome regulatory subunit 6B
(1)
26S proteasome regulatory subunit 7
(1)
26S proteasome regulatory subunit 8
(1)
Proteasome subunit alpha type-1
(1)
Proteasome subunit alpha type-2
(1)
Proteasome subunit alpha type-3
(1)
Proteasome subunit alpha type-4
(1)
Proteasome subunit alpha type-5
(1)
Proteasome subunit alpha type-6
(1)
Proteasome subunit alpha type-7
(1)
Proteasome subunit beta type-1
(1)
Proteasome subunit beta type-2
(1)
Proteasome subunit beta type-3
(1)
Proteasome subunit beta type-4
(1)
Proteasome subunit beta type-5
(1)
Proteasome subunit beta type-6
(1)
Proteasome subunit beta type-7
(1)
Thioredoxin-like protein 1
(1)
Ubiquitin-like modifier-activating enzyme 1
(1)
Ubiquitin-like modifier-activating enzyme 6
(1)
Interacting ligands
(1)
SO4 : SULFATE ION
(1)
Function and Biology
Biological function
(2)
proteasome binding
(5)
protein binding
(2)
Biological process
(13)
response to tumor necrosis factor
(5)
aggresome assembly
(2)
myeloid dendritic cell differentiation
(2)
positive regulation of apoptotic process
(2)
positive regulation of canonical NF-kappaB signal transduction
(2)
protein modification by small protein conjugation
(2)
protein ubiquitination
(2)
proteolysis
(2)
regulation of mitotic cell cycle phase transition
(2)
response to type II interferon
(2)
ubiquitin-dependent protein catabolic process
(2)
bioluminescence
(1)
generation of precursor metabolites and energy
(1)
Biological cell component
(6)
aggresome
(2)
cytoplasm
(2)
cytosol
(2)
fibrillar center
(2)
nucleoplasm
(2)
nucleus
(2)
Sequence and Structure classification
CATH class
(1)
Alpha Beta
(1)
CATH topology
(1)
Ubiquitin-like (UB roll)
(1)
Pfam accession / name
(2)
PF00240 : ubiquitin
(5)
PF01353 : GFP
(1)
Experimental Information
Diffraction protocol
(1)
Single wavelength
(2)
Diffraction radiation source type
(1)
Synchrotron
(2)
Diffraction source
(2)
ESRF BEAMLINE ID30B
(1)
SLS BEAMLINE X10SA
(1)
Synchrotron site
(2)
ESRF
(1)
SLS
(1)
Diffraction detector type
(1)
Pixel
(2)
Refinement software
(1)
PHENIX
(2)
EM microscope model
(1)
TFS KRIOS
(1)
EM detector name
(1)
GATAN K3 (6k x 4k)
(1)
NMR
NMR software packages
(8)
ARIA
(1)
Amber
(1)
CYANA
(1)
NMRPipe
(1)
NMRView
(1)
TALOS
(1)
TopSpin
(1)
XEASY
(1)
NMR Field Strength
500.0 - 600
(1)
600.0 - 700
(1)
700.0 - 800
(2)
800.0 - 900
(2)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 5 of 5
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The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome
Aichem A, Anders S, Catone N, Roessler P, Stotz S, Berg A, Schwab R, Scheuermann S, Bialas J, Schmidtke G, Peter C, Groettrup M, Wiesner S
Nat Commun
(2018)
[PMID: 30127417 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Ubiquitin D
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-127352 (Preferred)
search this ID

Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt2 at top of spiral staircase and partially unfolded Eos
Arkinson C, Gee CL, Martin A
bioRxiv
(2024)
[PMID: 39574680 ]
Source organisms: Lobophyllia hemprichii , Homo sapiens
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-281387 (Preferred)
search this ID
The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome
Aichem A, Anders S, Catone N, Roessler P, Stotz S, Berg A, Schwab R, Scheuermann S, Bialas J, Schmidtke G, Peter C, Groettrup M, Wiesner S
Nat Commun
(2018)
[PMID: 30127417 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
SO4
Assembly name:
Ubiquitin D
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-127352 (Preferred)
search this ID

Crystal structure of human UBA6 in complex with the ubiquitin-like modifier FAT10
Li S, Truongvan N, Schindelin H
Nat Commun
(2022)
[PMID: 35970836 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Ubiquitin-like modifier-activating enzyme 1, Ubiquitin-like modifier-activating enzyme 6 and Ubiquitin D
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-106055 (Preferred)
search this ID
Backbone 1H and 15N Chemical Shift Assignments for the first domain of FAT10
Wang W, Lim L, Qin H
Proc Natl Acad Sci U S A
(2014)
[PMID: 25422469 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Ubiquitin D
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-127352 (Preferred)
search this ID

Entries 1 to 5 of 5