Filter by :
Entry Information
Entry status
(1)
Experimental methods
(2)
Solution NMR
(4)
X-ray diffraction
(2)
Authors
(27)
Rosen MK
(4)
Abdul-Manan N
(2)
Kim AS
(2)
Liu GA
(2)
Ouerfelli O
(2)
Aghazadeh B
(1)
Bickford LC
(1)
Campellone KG
(1)
Cheng H-C
(1)
Cheng HC
(1)
Chereau D
(1)
Dominguez R
(1)
Grabarek Z
(1)
Graceffa P
(1)
Izard T
(1)
Kakalis LT
(1)
Kerff F
(1)
Kirschner MW
(1)
Langsetmo K
(1)
Leong JM
(1)
Majumdar A
(1)
Morgan D
(1)
Peterson JR
(1)
Siminovitch KA
(1)
Skehan BM
(1)
St-Jean M
(1)
Sygusch J
(1)
Homo / hetero assembly
(2)
hetero
(4)
homo
(2)
Assembly composition
(2)
protein/protein complex
(4)
protein structure
(2)
Assembly polymer count
(4)
dimer
(2)
monomer
(2)
octamer
(1)
trimer
(1)
Resolution distribution
2.0 - 2.5
(2)
Release year distribution
1995 - 2000
(2)
2000 - 2005
(3)
2005 - 2010
(3)
Journal
(4)
Nature
(3)
J Biol Chem
(1)
Nat Struct Mol Biol
(1)
Proc Natl Acad Sci U S A
(1)
Macromolecules
Organism superkingdom
(1)
Eukaryota
(6)
Organism name
(1)
Homo sapiens
(6)
Molecule name
(3)
Actin nucleation-promoting factor WAS
(6)
WASp
(6)
Wiskott-Aldrich syndrome protein
(6)
Molecule type
(1)
Protein
(6)
Gene names
(2)
IMD2
(6)
WAS
(6)
Interacting Molecules
(5)
Actin, alpha skeletal muscle
(1)
Cell division control protein 42 homolog
(1)
Deoxyribonuclease-1
(1)
ESPFU
(1)
Fructose-bisphosphate aldolase A
(1)
Interacting ligands
(1)
WSK : (2S)-1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL
(1)
Function and Biology
Biological function
(1)
actin binding
(1)
Biological process
(1)
actin filament organization
(4)
Sequence and Structure classification
SCOP fold
(1)
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
(2)
SCOP family
(1)
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain
(2)
CATH class
(1)
Alpha Beta
(4)
CATH topology
(1)
SerineThreonine-protein kinase PAK-alpha; Chain A
(4)
Pfam accession / name
(2)
PF00786 : PBD
(4)
PF02205 : WH2
(1)
Experimental Information
Diffraction protocol
(1)
Single wavelength
(3)
Diffraction radiation source type
(1)
Synchrotron
(2)
Diffraction source
(2)
APS BEAMLINE 17-ID
(1)
APS BEAMLINE 22-BM
(1)
Synchrotron site
(1)
APS
(2)
Diffraction detector type
(1)
CCD
(1)
Refinement software
(2)
CNS
(1)
REFMAC
(1)
NMR
NMR software packages
(6)
ARIA
(4)
NMRPipe
(4)
NMRView
(4)
CNS
(3)
X-PLOR
(3)
VNMR
(2)
NMR Field Strength
400.0 - 500
(2)
500.0 - 600
(4)
600.0 - 700
(4)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 6 of 6
Select all entries on this page
Solution Structure of the GTPase Binding Domain of WASP in Complex with EspFU, an EHEC Effector
Cheng H-C, Skehan BM, Campellone KG, Leong JM, Rosen MK
Nature
(2008)
[PMID: 18650809 ]
Source organisms: Escherichia coli O157:H7 , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Actin nucleation-promoting factor WAS
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-154864 (Preferred)
search this ID

SOLUTION STRUCTURE OF THE AUTOINHIBITED CONFORMATION OF WASP
Kim AS, Kakalis LT, Abdul-Manan N, Liu GA, Rosen MK
Nature
(2000)
[PMID: 10724160 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Actin nucleation-promoting factor WAS
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-154862 (Preferred)
search this ID

SOLUTION STRUCTURE OF CDC42 IN COMPLEX WITH THE GTPASE BINDING DOMAIN OF WASP
Abdul-Manan N, Aghazadeh B, Liu GA, Majumdar A, Ouerfelli O, Rosen MK
Nature
(1999)
[PMID: 10360578 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Actin nucleation-promoting factor WAS and Cell division control protein 42 homolog
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-154863 (Preferred)
search this ID
Fructose-1,6-bisphosphate aldolase from rabbit muscle in complex with a C-terminal peptide of Wiskott-Aldrich syndrome protein
St-Jean M, Izard T, Sygusch J
J Biol Chem
(2007)
[PMID: 17329259 ]
Source organisms: Oryctolagus cuniculus , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Actin nucleation-promoting factor WAS and Fructose-bisphosphate aldolase A
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-133667 (Preferred)
search this ID
Ternary complex of the WH2 domain of WASP with Actin-DNAse I
Chereau D, Kerff F, Dominguez R
Proc Natl Acad Sci U S A
(2005)
[PMID: 16275905 ]
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
NAG(2)
PDBe complex ID:
PDB-CPX-132781 (Preferred)
search this ID
Solution structure of the Wiskott-Aldrich Syndrome Protein (WASP) autoinhibited core domain complexed with (S)-wiskostatin, a small molecule inhibitor
Peterson JR, Bickford LC, Morgan D, Kim AS, Ouerfelli O, Kirschner MW, Rosen MK
Nat Struct Mol Biol
(2004)
[PMID: 15235593 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Actin nucleation-promoting factor WAS
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-154862 (Preferred)
search this ID

Entries 1 to 6 of 6