Uniprot accession / id : P70362  OR   Uniprot accession / id : Q92890
 
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Entry Information
Entry status  (1)
REL
(4)
 
Experimental methods  (2)
X-ray diffraction
(3)
Solution NMR
(1)
 
Authors  (26)
Kang W
(2)
Le LTM
(2)
Yang JK
(2)
Haenzelmann P
(1)
Han BW
(1)
Hanzelmann P
(1)
Hänzelmann P
(1)
Kigawa T
(1)
Kim DH
(1)
Kim HS
(1)
Kim JY
(1)
Kim Nguyen YT
(1)
Ko KS
(1)
Le LT
(1)
Le OT
(1)
Le OTT
(1)
Lee HT
(1)
Lee SY
(1)
My Le LT
(1)
Nguyen TQ
(1)
Nguyen YTK
(1)
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
(1)
Saito K
(1)
Schindelin H
(1)
Tomizawa T
(1)
Yokoyama S
(1)
 
Homo / hetero assembly  (2)
hetero
(3)
homo
(1)
 
Assembly composition  (2)
protein/protein complex
(3)
protein structure
(1)
 
Assembly polymer count  (3)
dimer
(2)
monomer
(1)
octamer
(1)
 
Resolution distribution
1.5 - 2
(1)
2.5 - 3
(1)
3.0 - 3.5
(1)
 
Release year distribution
2005 - 2010
(1)
2015 - 2020
(2)
2020 - 2025
(1)
 
Journal  (3)
Structure
(2)
PLoS One
(1)
To be published
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(4)
 
Organism name  (1)
Homo sapiens
(4)
 
Molecule name  (3)
UB fusion protein 1
(4)
Ubiquitin fusion degradation protein 1
(4)
Ubiquitin recognition factor in ER-associated degradation protein 1
(4)
 
Molecule type  (1)
Protein
(4)
 
Gene names  (2)
UFD1
(4)
UFD1L
(4)
 
Interacting Molecules  (2)
Transitional endoplasmic reticulum ATPase
(2)
Nuclear protein localization protein 4 homolog
(1)
 
Function and Biology
Biological process  (1)
ubiquitin-dependent protein catabolic process
(1)
 
Sequence and Structure classification
CATH class  (2)
Alpha Beta
(1)
Mainly Beta
(1)
 
CATH topology  (2)
Barwin-like endoglucanases
(1)
Vcp-like ATPase; Chain A, domain 2
(1)
 
Pfam accession / name  (1)
PF03152 : UFD1
(1)
 
Experimental Information
Diffraction radiation source type  (1)
Synchrotron
(3)
 
Diffraction source  (2)
PAL/PLS BEAMLINE 5C (4A)
(2)
ESRF BEAMLINE ID29
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 4 of 4
Entries 1 to 4 of 4
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Solution structure of human ubiquitin fusion degradation protein 1 homolog UFD1
Saito K, Tomizawa T, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Ubiquitin recognition factor in ER-associated degradation protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-187801 (Preferred)   search this ID
PDBe-KB: Q92890   
Solution NMR
Released: 15 Apr 2008
Model geometry
Fit model/data
Data not deposited
2yuj
2yuj
2yuj
Structural Details of Ufd1 binding to p97
Le LTM, Yang JK
PLoS One (2016) [PMID: 27684549  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Transitional endoplasmic reticulum ATPase and Ubiquitin recognition factor in ER-associated degradation protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157172 (Preferred)   search this ID
PDBe-KB: Q92890    P55072   
X-ray diffraction
1.55Å resolution
Released: 4 Jan 2017
Model geometry
Fit model/data
5b6c
5b6c
5b6c
p97-delta709-728 in complex with a UFD1-SHP peptide
Haenzelmann P, Schindelin H
Structure (2016) [PMID: 26712280  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: MG    GOL    CL    MG    AGS    AGS   
Assembly name: Transitional endoplasmic reticulum ATPase and Ubiquitin recognition factor in ER-associated degradation protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157193 (Preferred)   search this ID
PDBe-KB: Q92890    P55072   
X-ray diffraction
3.08Å resolution
Released: 13 Jan 2016
Model geometry
Fit model/data
5c1b
5c1b
5c1b
Crystal structure of human Ufd1-Npl4 complex
Nguyen TQ, Le LTM, Kim DH, Ko KS, Lee HT, Nguyen YTK, Kim HS, Han BW, Kang W, Yang JK
Structure (2022) [PMID: 36087575  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Nuclear protein localization protein 4 homolog and Ubiquitin recognition factor in ER-associated degradation protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-186161 (Preferred)   search this ID
PDBe-KB: Q92890    Q8TAT6   
X-ray diffraction
2.72Å resolution
Released: 21 Sep 2022
Model geometry
Fit model/data
7wwq
7wwq
7wwq
Entries 1 to 4 of 4
Entries 1 to 4 of 4