Entry status  (1)

REL

(4)

Experimental methods  (2)

Electron Microscopy

(3)

X-ray diffraction

(1)

Authors  (11)

Cong Y

(3)

Li Z

(3)

Lou X

(3)

Wang T

(3)

Wu T

(3)

Yan N

(3)

Yang X

(3)

Leahy DJ

(1)

Mori MX

(1)

Vander Kooi CW

(1)

Yue DT

(1)

Homo / hetero assembly  (1)

hetero

(4)

Assembly composition  (1)

protein/protein complex

(4)

Assembly polymer count  (3)

trimer

(2)

dimer

(1)

tetramer

(1)

Resolution distribution

2.5 - 3

(3)

3.0 - 3.5

(1)

Release year distribution

2005 - 2010

(1)

2020 - 2025

(3)

Journal  (2)

Cell Res

(3)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(4)

Organism name  (1)

Homo sapiens

(4)

Molecule name  (5)

BI

(4)

Brain calcium channel I

(4)

Calcium channel, L type, alpha-1 polypeptide isoform 4

(4)

Voltage-dependent P/Q-type calcium channel subunit alpha-1A

(4)

Voltage-gated calcium channel subunit alpha Cav2.1

(4)

Molecule type  (1)

Protein

(4)

Gene names  (4)

CACH4

(4)

CACN3

(4)

CACNA1A

(4)

CACNL1A4

(4)

Interacting Molecules  (4)

Voltage-dependent L-type calcium channel subunit beta-3

(3)

Voltage-dependent calcium channel subunit alpha-2/delta-1

(3)

Calmodulin-1

(1)

Omega-conotoxin MVIIC

(1)

Interacting ligands  (7)

3PE : 1,2-Distearoyl-sn-glycerophosphoethanolamine

(3)

CA : CALCIUM ION

(3)

CLR : CHOLESTEROL

(3)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(3)

PT5 : [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate

(3)

Y01 : CHOLESTEROL HEMISUCCINATE

(3)

PS1 : 1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE]

(1)

Biological function  (8)

amyloid-beta binding

(3)

calcium channel activity

(3)

high voltage-gated calcium channel activity

(3)

metal ion binding

(3)

monoatomic ion channel activity

(3)

protein binding

(3)

syntaxin binding

(3)

voltage-gated calcium channel activity

(3)

Biological process  (10)

calcium ion import across plasma membrane

(3)

calcium ion transmembrane transport

(3)

calcium ion transport

(3)

cellular response to amyloid-beta

(3)

modulation of chemical synaptic transmission

(3)

monoatomic ion transmembrane transport

(3)

monoatomic ion transport

(3)

positive regulation of cytosolic calcium ion concentration

(3)

response to amyloid-beta

(3)

transmembrane transport

(3)

Biological cell component  (8)

cell projection

(3)

cytoplasm

(3)

membrane

(3)

monoatomic ion channel complex

(3)

neuronal cell body

(3)

nucleus

(3)

plasma membrane

(3)

voltage-gated calcium channel complex

(3)

Pfam accession / name  (4)

PF00520 : Ion_trans

(3)

PF08016 : PKD_channel

(3)

PF08763 : Ca_chan_IQ

(3)

PF16905 : GPHH

(3)

Diffraction protocol  (1)

Single wavelength

(1)

Diffraction radiation source type  (1)

Rotating anode

(1)

Diffraction source  (1)

RIGAKU RU200

(1)

Refinement software  (1)

REFMAC

(1)

EM microscope model  (1)

FEI TITAN KRIOS

(3)

EM detector name  (1)

GATAN K3 (6k x 4k)

(3)

Representative Structures

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