Entry status  (1)

REL

(16)

Experimental methods  (2)

X-ray diffraction

(14)

Electron Microscopy

(2)

Authors  (87)

Downs JA

(4)

Hyvonen M

(4)

Hyvönen M

(4)

Pantelejevs T

(4)

Zuazua-Villar P

(4)

Counsell AJ

(3)

Koczy O

(3)

Miron S

(3)

Pellegrini L

(3)

Robertson NS

(3)

Spring DR

(3)

Walsh SJ

(3)

Zinn-Justin S

(3)

Appleby R

(2)

Chen PL

(2)

Cobbett K

(2)

Jeffrey PD

(2)

Joudeh L

(2)

Kanaar R

(2)

Kinnucan E

(2)

Lee WH

(2)

Legrand P

(2)

Miller J

(2)

Pavletich NP

(2)

Sun Y

(2)

Thoma NH

(2)

Yang H

(2)

Zelensky AN

(2)

Zheng N

(2)

van Rossum-Fikkert SE

(2)

Agrawal R

(1)

Anand S

(1)

Ashworth A

(1)

Baarends WM

(1)

Beaurepere R

(1)

Blundell TL

(1)

Boucherit V

(1)

Butz M

(1)

Carreira A

(1)

Davies OR

(1)

Duchambon P

(1)

Dunce JM

(1)

Dupaigne P

(1)

Ehlen A

(1)

Ehlén Å

(1)

El Marjou A

(1)

Essers J

(1)

Felipe-Medina N

(1)

Ghouil R

(1)

Gielen F

(1)

Hollfelder F

(1)

Julien M

(1)

Kaminski CF

(1)

Koornneef L

(1)

Le Du MH

(1)

Lee M

(1)

Lindenburg L

(1)

Lindenburg LH

(1)

Lo T

(1)

Longo MA

(1)

Lord CJ

(1)

Maas A

(1)

Majeed A

(1)

Martin C

(1)

Nandakumar J

(1)

Oliver AW

(1)

Paul MW

(1)

Pearl LH

(1)

Pendas AM

(1)

Pendlebury DF

(1)

Perera R

(1)

Rees E

(1)

Ristic D

(1)

Ropars V

(1)

Sessa G

(1)

Shibuya H

(1)

Sleddens-Linkels E

(1)

Swift S

(1)

Syed MA

(1)

Tainer JA

(1)

Theillet FX

(1)

Tsai C-L

(1)

Veerman J

(1)

Venkitaraman AR

(1)

Yu DS

(1)

Zhang J

(1)

van Loon Y

(1)

Homo / hetero assembly  (1)

hetero

(16)

Assembly composition  (2)

protein/protein complex

(13)

DNA/protein complex

(3)

Assembly polymer count  (9)

dimer

(8)

21-mer

(1)

22-mer

(1)

hexadecamer

(1)

hexamer

(1)

octamer

(1)

pentadecamer

(1)

tetramer

(1)

trimer

(1)

Resolution distribution

1.0 - 1.5

(1)

1.5 - 2

(3)

2.0 - 2.5

(1)

2.5 - 3

(5)

3.0 - 3.5

(6)

Release year distribution

2000 - 2005

(3)

2005 - 2010

(1)

2015 - 2020

(2)

2020 - 2025

(10)

Journal  (9)

Nat Commun

(5)

Chem Sci

(3)

Science

(2)

EMBO Rep

(1)

Nat Struct Mol Biol

(1)

Nature

(1)

Nucleic Acids Res

(1)

Proc Natl Acad Sci U S A

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(16)

Organism name  (2)

Homo sapiens

(14)

Mus musculus

(2)

Molecule name  (8)

Breast cancer type 2 susceptibility protein

(14)

Fanconi anemia group D1 protein

(14)

Breast cancer type 2 susceptibility protein homolog

(2)

Fanconi anemia group D1 protein homolog

(2)

DNA repair protein RAD51 homolog 1

(1)

HsRAD51

(1)

RAD51 homolog A

(1)

hRAD51

(1)

Molecule type  (1)

Protein

(16)

Gene names  (8)

BRCA2

(14)

FACD

(14)

FANCD1

(14)

Brca2

(2)

Fancd1

(2)

RAD51

(1)

RAD51A

(1)

RECA

(1)

Interacting Molecules  (14)

DNA repair protein RAD51 homolog 1

(5)

DNA repair and recombination protein RadA

(4)

26S proteasome complex subunit SEM1

(2)

Heat shock factor 2-binding protein

(2)

Meiotic recombination protein DMC1/LIM15 homolog

(2)

5'-D(P*TP*TP*TP*TP*TP*T)-3'

(1)

ARTIFICIAL GLY-SER-MSE-GLY PEPTIDE

(1)

Breast cancer type 2 susceptibility protein

(1)

DNA (30-MER)

(1)

DNA strand 1

(1)

DNA strand 2

(1)

Partner and localizer of BRCA2

(1)

Serine/threonine-protein kinase PLK1

(1)

peptide linker

(1)

Interacting ligands  (6)

RF6 : 4,6-diethylpyrimidin-2-amine

(2)

ADP : ADENOSINE-5'-DIPHOSPHATE

(1)

BEF : BERYLLIUM TRIFLUORIDE ION

(1)

EDO : 1,2-ETHANEDIOL

(1)

HG : MERCURY (II) ION

(1)

TKI : 2-[(4,6-diethyl-1,3,5-triazin-2-yl)-methyl-amino]ethanoic acid

(1)

Biological function  (8)

ATP binding

(1)

ATP hydrolysis activity

(1)

ATP-dependent DNA damage sensor activity

(1)

ATP-dependent activity, acting on DNA

(1)

DNA binding

(1)

DNA strand exchange activity

(1)

double-stranded DNA binding

(1)

single-stranded DNA binding

(1)

Biological process  (4)

DNA repair

(3)

double-strand break repair via homologous recombination

(3)

DNA metabolic process

(1)

mitotic recombination-dependent replication fork processing

(1)

SCOP fold  (4)

BRCA2 helical domain

(2)

BRCA2 tower domain

(2)

OB-fold

(2)

BRCA2 BRC4 repeat

(1)

SCOP family  (4)

BRCA2 helical domain

(2)

BRCA2 tower domain

(2)

Single strand DNA-binding domain, SSB

(2)

BRCA2 BRC4 repeat

(1)

CATH class  (2)

Mainly Beta

(2)

Special

(1)

CATH topology  (2)

OB fold (Dihydrolipoamide Acetyltransferase, E2P)

(2)

Topoisomerase I; Chain A, domain 4

(1)

Pfam accession / name  (8)

PF00634 : BRCA2

(6)

PF22687 : BRCA2_TR2

(3)

PF09103 : BRCA-2_OB1

(2)

PF09104 : BRCA-2_OB3

(2)

PF09121 : Tower

(2)

PF09169 : BRCA-2_helical

(2)

PF21318 : BRCA2DBD_OB2

(2)

PF08423 : Rad51

(1)

Diffraction protocol  (2)

Single wavelength

(13)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(14)

Diffraction source  (9)

DIAMOND BEAMLINE I04

(3)

CHESS BEAMLINE A1

(2)

DIAMOND BEAMLINE I03

(2)

SOLEIL BEAMLINE PROXIMA 1

(2)

APS BEAMLINE 21-ID-D

(1)

ESRF BEAMLINE ID14-1

(1)

ESRF BEAMLINE ID29

(1)

ESRF BEAMLINE MASSIF-1

(1)

SSRL BEAMLINE BL9-2

(1)

Synchrotron site  (6)

Diamond

(5)

ESRF

(3)

CHESS

(2)

SOLEIL

(2)

APS

(1)

SSRL

(1)

Diffraction detector type  (2)

Pixel

(10)

CCD

(4)

Refinement software  (3)

BUSTER

(7)

PHENIX

(7)

CNS

(3)

EM microscope model  (1)

FEI TITAN KRIOS

(2)

EM detector name  (1)

GATAN K3 (6k x 4k)

(2)

Representative Structures

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