Uniprot accession / id : Q03157  OR   Uniprot accession / id : P51693  OR   Uniprot accession / id : K7EQJ4
remove all filters
 
Filter by :
Entry Information
Entry status  (1)
REL
(6)
 
Experimental methods  (1)
X-ray diffraction
(6)
 
Authors  (12)
Ha Y
(4)
Lee S
(4)
Xue Y
(4)
Wang Y
(3)
Dahms SO
(2)
Mayer MC
(2)
Multhaup G
(2)
Roeser D
(2)
Than ME
(2)
Demeler B
(1)
Hu J
(1)
Liu X
(1)
 
Homo / hetero assembly  (1)
homo
(6)
 
Assembly composition  (1)
protein structure
(6)
 
Assembly polymer count  (1)
dimer
(6)
 
Resolution distribution
2.0 - 2.5
(5)
2.5 - 3
(1)
 
Release year distribution
2010 - 2015
(6)
2015 - 2020
(2)
 
Journal  (4)
Acta Crystallogr D Biol Crystallogr
(2)
J Biol Chem
(2)
Biochemistry
(1)
Proc Natl Acad Sci U S A
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(6)
 
Organism name  (1)
Homo sapiens
(6)
 
Molecule name  (6)
APLP
(6)
APLP-1
(6)
Amyloid beta (A4) precursor-like protein 1
(6)
Amyloid beta precursor like protein 1
(6)
Amyloid-like protein 1
(6)
C30
(6)
 
Molecule type  (1)
Protein
(6)
 
Gene names  (1)
APLP1
(6)
 
Interacting ligands  (9)
IDS : 2-O-sulfo-alpha-L-idopyranuronic acid
(2)
SGN : 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose
(2)
SO4 : SULFATE ION
(2)
GU4 : 2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose
(1)
PO4 : PHOSPHATE ION
(1)
PRD_900013 : sucrose octasulfate
(1)
UAP : 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid
(1)
YYJ : 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose
(1)
ZN : ZINC ION
(1)
 
Function and Biology
Biological cell component  (1)
membrane
(6)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(6)
 
CATH topology  (1)
Four Helix Bundle (Hemerythrin (Met), subunit A)
(6)
 
Pfam accession / name  (1)
PF12925 : APP_E2
(6)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(6)
 
Diffraction radiation source type  (1)
Synchrotron
(6)
 
Diffraction source  (3)
BESSY BEAMLINE 14.1
(2)
NSLS BEAMLINE X25
(2)
NSLS BEAMLINE X29A
(2)
 
Synchrotron site  (2)
NSLS
(4)
BESSY
(2)
 
Diffraction detector type  (2)
CCD
(4)
Pixel
(1)
 
Refinement software  (3)
REFMAC
(3)
PHENIX
(2)
CNS
(1)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
Entries 1 to 6 of 6
Entries 1 to 6 of 6
 Select all entries on this page
4rd9
X-RAY STRUCTURE OF THE APO FORM OF THE AMYLOID PRECURSOR PROTEIN-LIKE PROTEIN 1 (APLP1) E2 DOMAIN
Dahms SO, Than ME
Acta Crystallogr D Biol Crystallogr (2015) [PMID: 25760599  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Amyloid beta precursor like protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-156407 (Preferred)   search this ID
PDBe-KB: P51693   
X-ray diffraction
2.6Å resolution
Released: 11 Mar 2015
DOI: 10.2210/pdb4rd9  
Model geometry
Fit model/data
4rd9
4rd9
4rd9
4rda
X-RAY STRUCTURE OF THE AMYLOID PRECURSOR PROTEIN-LIKE PROTEIN 1 (APLP1) E2 DOMAIN IN COMPLEX WITH A HEPARIN DODECASACCHARIDE
Dahms SO, Than ME
Acta Crystallogr D Biol Crystallogr (2015) [PMID: 25760599  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: ZN    ZN   
Carbohydrate polymer components:
Molecule 1 - IDS(2), SGN(2), UAP(1)
Molecule 2 - IDS(3), SGN(3)
Assembly name: Amyloid beta precursor like protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-156407 (Preferred)   search this ID
PDBe-KB: P51693   
X-ray diffraction
2.497Å resolution
Released: 11 Mar 2015
DOI: 10.2210/pdb4rda  
Model geometry
Fit model/data
4rda
4rda
4rda
3q7l
Crystal structure of the E2 domain of amyloid precursor-like protein 1
Xue Y, Ha Y
J Biol Chem (2011) [PMID: 21715329  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: SO4   
Assembly name: Amyloid beta precursor like protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-156407 (Preferred)   search this ID
PDBe-KB: P51693   
X-ray diffraction
2.2Å resolution
Released: 29 Jun 2011
DOI: 10.2210/pdb3q7l  
Model geometry
Fit model/data
3q7l
3q7l
3q7l
3pmr
Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1
Lee S, Xue Y, Hu J, Wang Y, Liu X, Demeler B, Ha Y
Biochemistry (2011) [PMID: 21574595  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: PO4   
Assembly name: Amyloid beta precursor like protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-156407 (Preferred)   search this ID
PDBe-KB: P51693   
X-ray diffraction
2.11Å resolution
Released: 1 Jun 2011
DOI: 10.2210/pdb3pmr  
Model geometry
Fit model/data
3pmr
3pmr
3pmr
3q7g
Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)
Xue Y, Ha Y
J Biol Chem (2011) [PMID: 21715329  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Carbohydrate polymer components:
Molecule 1 - GU4(1), YYJ(1)
Assembly name: Amyloid beta precursor like protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-156407 (Preferred)   search this ID
PDBe-KB: P51693   
X-ray diffraction
2.3Å resolution
Released: 22 Jun 2011
DOI: 10.2210/pdb3q7g  
Model geometry
Fit model/data
3q7g
3q7g
3q7g
3qmk
Crystal structure of the E2 domain of APLP1 in complex with heparin hexasaccharide
Xue Y, Ha Y
Proc Natl Acad Sci U S A (2011) [PMID: 21930949  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: SO4   
Carbohydrate polymer components:
Molecule 1 - IDS(2), SGN(2)
Assembly name: Amyloid beta precursor like protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-156407 (Preferred)   search this ID
PDBe-KB: P51693   
X-ray diffraction
2.21Å resolution
Released: 12 Oct 2011
DOI: 10.2210/pdb3qmk  
Model geometry
Fit model/data
3qmk
3qmk
3qmk
Entries 1 to 6 of 6
Entries 1 to 6 of 6