Entry status  (1)

REL

(23)

Experimental methods  (1)

X-ray diffraction

(23)

Authors  (95)

Appiah KK

(13)

Beno BR

(13)

Bronson J

(13)

Dzierba C

(13)

Gao M

(13)

Gerritz SW

(13)

Goldfarb V

(13)

Huang Y

(13)

Kiefer SE

(13)

Kish K

(13)

Kostich WA

(13)

Macor JE

(13)

McDonnell PA

(13)

O'Connell J

(13)

Sheriff S

(13)

Shi S

(13)

Westphal RS

(13)

Yanchunas J

(13)

Zhai W

(13)

Zhu S

(13)

Bouyain S

(5)

Watkins DJ

(3)

Agarwal R

(2)

Alfano I

(2)

Almo SC

(2)

Alvarado J

(2)

Arrowsmith C

(2)

Barr AJ

(2)

Bonanno JB

(2)

Burgess-Brown NA

(2)

Burley SK

(2)

Chance MR

(2)

Dilorenzo TP

(2)

Dubreuil V

(2)

Edwards A

(2)

Emtage S

(2)

Eswaramoorthy S

(2)

Faber-Barata J

(2)

Filippakopoulos P

(2)

Fiser A

(2)

Hall DR

(2)

Hammel M

(2)

Harroch S

(2)

Jin X

(2)

Karuppan SJ

(2)

King ON

(2)

Knapp S

(2)

Kumaran D

(2)

Lawrence DS

(2)

Lee WH

(2)

Madegowda M

(2)

Malashkevich V

(2)

Mehzabeen N

(2)

Muller S

(2)

Müller S

(2)

New York SGX Research Center for Structural Genomics (NYSGXRC)

(2)

Nikolaienko RM

(2)

Patskovsky Y

(2)

Ragumani S

(2)

Ramagopal UA

(2)

Reyes C

(2)

Sali A

(2)

Sauder JM

(2)

Savitsky P

(2)

Smith D

(2)

Stella SL

(2)

Structural Genomics Consortium (SGC)

(2)

Sundstrom M

(2)

Swaminathan S

(2)

Ugochukwu E

(2)

Wasserman SR

(2)

Zalmai R

(2)

Zhang ZY

(2)

von Delft F

(2)

Bain KT

(1)

Barr A

(1)

Bera A

(1)

Cheng W

(1)

Das S

(1)

Debreczeni J

(1)

Eswaran J

(1)

Freeman J

(1)

Freeman JC

(1)

Gileadi O

(1)

Johansson C

(1)

Ju C

(1)

Lv Z

(1)

Min T

(1)

Mu H

(1)

Ni C

(1)

Pelletier L

(1)

Shapiro L

(1)

Wang F

(1)

Wasserman S

(1)

Weigelt J

(1)

Homo / hetero assembly  (2)

homo

(20)

hetero

(3)

Assembly composition  (2)

protein structure

(20)

protein/protein complex

(3)

Assembly polymer count  (2)

monomer

(20)

dimer

(3)

Resolution distribution

1.5 - 2

(7)

2.0 - 2.5

(13)

2.5 - 3

(3)

Release year distribution

2005 - 2010

(7)

2010 - 2015

(13)

2015 - 2020

(2)

2020 - 2025

(1)

Journal  (6)

J Med Chem

(13)

Proc Natl Acad Sci U S A

(3)

Cell

(2)

J Biol Chem

(2)

J Struct Funct Genomics

(2)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(23)

Organism name  (2)

Homo sapiens

(20)

Mus musculus

(3)

Molecule name  (3)

Protein-tyrosine phosphatase gamma

(23)

R-PTP-gamma

(23)

Receptor-type tyrosine-protein phosphatase gamma

(23)

Molecule type  (1)

Protein

(23)

Gene names  (3)

PTPG

(20)

PTPRG

(20)

Ptprg

(3)

Interacting Molecules  (3)

Contactin-3

(1)

Contactin-4

(1)

Contactin-6

(1)

Interacting ligands  (20)

SO4 : SULFATE ION

(5)

VO4 : VANADATE ION

(3)

ACY : ACETIC ACID

(2)

FMT : FORMIC ACID

(2)

MLI : MALONATE ION

(2)

NXY : 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid

(2)

1PS : 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE

(1)

ACT : ACETATE ION

(1)

CL : CHLORIDE ION

(1)

EDO : 1,2-ETHANEDIOL

(1)

FLC : CITRATE ANION

(1)

MES : 2-(N-MORPHOLINO)-ETHANESULFONIC ACID

(1)

NA : SODIUM ION

(1)

NX1 : 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid

(1)

NX2 : 3-[(3,4-dichlorobenzyl)sulfanyl]-N-(methylsulfonyl)thiophene-2-carboxamide

(1)

NX3 : N-[(3-aminophenyl)sulfonyl]-3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxamide

(1)

NX4 : 5-[({3-[(3,4-dichlorobenzyl)sulfanyl]thiophen-2-yl}carbonyl)sulfamoyl]-2-methoxybenzoic acid

(1)

NX5 : 2-[(3,4-dichlorobenzyl)sulfanyl]benzoic acid

(1)

NXV : 2-[(3,4-dichlorobenzyl)sulfanyl]-4-(4-hydroxybut-1-yn-1-yl)benzoic acid

(1)

NXW : 2-[(3,4-dichlorobenzyl)sulfanyl]-4-{[3-({N-[2-(methylamino)ethyl]glycyl}amino)phenyl]ethynyl}benzoic acid

(1)

EC number / name  (1)

3.1.3.48 : Protein-tyrosine-phosphatase

(23)

Biological function  (3)

protein tyrosine phosphatase activity

(18)

carbonate dehydratase activity

(5)

zinc ion binding

(5)

Biological process  (2)

dephosphorylation

(18)

protein dephosphorylation

(18)

CATH class  (1)

Alpha Beta

(22)

CATH topology  (2)

Protein-Tyrosine Phosphatase; Chain A

(17)

Carbonic Anhydrase II

(5)

Pfam accession / name  (2)

PF00102 : Y_phosphatase

(18)

PF00194 : Carb_anhydrase

(5)

Diffraction protocol  (1)

Single wavelength

(23)

Diffraction radiation source type  (2)

Synchrotron

(12)

Rotating anode

(11)

Diffraction source  (10)

RIGAKU FR-E SUPERBRIGHT

(9)

APS BEAMLINE 17-ID

(3)

APS BEAMLINE 22-ID

(3)

APS BEAMLINE 22-BM

(2)

CLSI BEAMLINE 08ID-1

(1)

NSLS BEAMLINE X29A

(1)

NSLS BEAMLINE X4A

(1)

RIGAKU

(1)

RIGAKU FR-E

(1)

SLS BEAMLINE X10SA

(1)

Synchrotron site  (4)

APS

(8)

NSLS

(2)

CLSI

(1)

SLS

(1)

Diffraction detector type  (3)

CCD

(13)

Image plate

(9)

Pixel

(1)

Refinement software  (6)

CNS

(10)

CNX

(10)

PHENIX

(5)

REFMAC

(5)

BUSTER

(3)

BUSTER-TNT

(2)

Representative Structures

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