Entry status  (1)

REL

(5)

Experimental methods  (1)

X-ray diffraction

(5)

Authors  (44)

Barf T

(2)

Barker J

(2)

Cheng RKY

(2)

Felicetti B

(2)

Hesterkamp T

(2)

Kaptein A

(2)

Kazemier B

(2)

Oubrie A

(2)

Palan S

(2)

Schultz-Fademrecht C

(2)

Whittaker M

(2)

de Roos J

(2)

van Hoek M

(2)

van de Kar B

(2)

van der Heijden R

(2)

Borsboom J

(1)

Cheng R

(1)

Croll TI

(1)

Demont D

(1)

Goorden R

(1)

Heijden R

(1)

Hoek M

(1)

Hofstra C

(1)

Hoogenboom N

(1)

Hornberg J

(1)

Kar B

(1)

Klop H

(1)

Lommerse J

(1)

Read RJ

(1)

Roos J

(1)

Scheffers M

(1)

Scheich C

(1)

Seegers N

(1)

Smeets R

(1)

Someren R

(1)

Toogood-Johnson I

(1)

Versteegh J

(1)

Wilde S

(1)

Zeeland M

(1)

de Kimpe V

(1)

de Wilde S

(1)

de Zwart E

(1)

van Someren R

(1)

van Zeeland M

(1)

Homo / hetero assembly  (1)

homo

(5)

Assembly composition  (1)

protein structure

(5)

Assembly polymer count  (1)

monomer

(5)

Resolution distribution

1.5 - 2

(3)

2.0 - 2.5

(2)

Release year distribution

2005 - 2010

(2)

2010 - 2015

(3)

2020 - 2025

(1)

Journal  (4)

Bioorg Med Chem Lett

(2)

Acta Crystallogr D Struct Biol

(1)

Protein Sci

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(5)

Organism name  (1)

Homo sapiens

(5)

Molecule name  (8)

3pK

(5)

Chromosome 3p kinase

(5)

MAP kinase-activated protein kinase 3

(5)

MAPK-activated protein kinase 3

(5)

MAPKAP kinase 3

(5)

MAPKAP-K3

(5)

MAPKAPK-3

(5)

MK-3

(5)

Molecule type  (1)

Protein

(5)

Gene names  (1)

MAPKAPK3

(5)

Interacting ligands  (4)

P4O : 2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE

(2)

05B : 2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one

(1)

F10 : 2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE

(1)

I85 : N-{4-[(3S)-4'-oxo-1',4',5',6'-tetrahydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-2'-yl]pyridin-2-yl}-3-(trifluoromethyl)benzamide

(1)

EC number / name  (1)

2.7.11.1 : Non-specific serine/threonine protein kinase

(5)

Biological function  (2)

ATP binding

(5)

protein kinase activity

(5)

Biological process  (1)

protein phosphorylation

(5)

Representative Structures

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