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(1)
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(2)
X-ray diffraction
(12)
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(1)
Authors
(69)
Schlundt A
(7)
Janowski R
(6)
Niessing D
(6)
Heissmeyer V
(5)
Heinz GA
(4)
Sattler M
(4)
Tants JN
(3)
Weigand JE
(3)
Babon JJ
(2)
Binas O
(2)
Blank M
(2)
Braun J
(2)
Brenner S
(2)
Buch T
(2)
Buhmann R
(2)
Davydova E
(2)
Geerlof A
(2)
Gruber AR
(2)
Kershaw NJ
(2)
Kiledjian M
(2)
Peter SA
(2)
Schwalbe H
(2)
Stehle R
(2)
Tan D
(2)
Tants J-N
(2)
Tong L
(2)
Vinuesa CG
(2)
Wommelsdorf N
(2)
Zavolan M
(2)
Zhou M
(2)
Alderton D
(1)
Arrowsmith CH
(1)
Athanasopoulos V
(1)
Berrow NS
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Bountra C
(1)
Brown SH
(1)
Brown SHJ
(1)
Chong MM
(1)
Chong MMW
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Cockburn JB
(1)
Dixon NE
(1)
Dong A
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Duan G
(1)
Edwards AM
(1)
Heinemann U
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Hu D
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Jergic S
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Jones EY
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Landthaler M
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Li Y
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Murakawa Y
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Oberstrass L
(1)
Ose T
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Owens RJ
(1)
Patel HR
(1)
Pratama A
(1)
Preiss T
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Richards S
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Rosenbaum E
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Schuetz A
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Srivastava M
(1)
Structural Genomics Consortium (SGC)
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Stuart D
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Tempel W
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Tong Y
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Verma A
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Yeo JH
(1)
Zhang Q
(1)
kershaw NJ
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Homo / hetero assembly
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hetero
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homo
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RNA/protein complex
(7)
protein structure
(6)
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(3)
dimer
(7)
monomer
(5)
trimer
(1)
Resolution distribution
1.5 - 2
(5)
2.0 - 2.5
(3)
2.5 - 3
(4)
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2010 - 2015
(8)
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(8)
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Macromolecules
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(1)
Eukaryota
(13)
Organism name
(2)
Mus musculus
(7)
Homo sapiens
(6)
Molecule name
(6)
RING finger and C3H zinc finger protein 1
(13)
RING finger and CCCH-type zinc finger domain-containing protein 1
(13)
Roquin
(13)
Roquin-1
(13)
Protein Sanroque
(7)
RING finger protein 198
(6)
Molecule type
(1)
Protein
(13)
Gene names
(6)
Gm551
(7)
Kiaa2025
(7)
Rc3h1
(7)
KIAA2025
(6)
RC3H1
(6)
RNF198
(6)
Interacting Molecules
(7)
5'-R(*AP*C*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3'
(1)
5'-R(*CP*UP*CP*CP*CP*UP*UP*CP*UP*GP*UP*GP*AP*AP*GP*GP*GP*GP*A)-3'
(1)
RNA (5'-R(*AP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3')
(1)
RNA (5'-R(P*CP*CP*AP*CP*AP*CP*CP*GP*UP*UP*CP*UP*AP*GP*GP*UP*GP*CP*UP*GP*G)-3')
(1)
RNA (5'-R(P*GP*GP*AP*AP*AP*UP*UP*AP*UP*AP*UP*UP*AP*AP*UP*UP*UP*CP*C)-3')
(1)
RNA (5'-R(P*GP*GP*UP*GP*CP*CP*UP*AP*AP*UP*AP*UP*UP*UP*AP*GP*GP*CP*AP*CP*(CCC))-3')
(1)
RNA (5'-R(P*UP*GP*AP*CP*UP*GP*CP*GP*UP*UP*UP*UP*AP*GP*GP*AP*GP*UP*UP*A)-3')
(1)
Interacting ligands
(6)
CL : CHLORIDE ION
(4)
EDO : 1,2-ETHANEDIOL
(2)
GOL : GLYCEROL
(2)
ZN : ZINC ION
(2)
IOD : IODIDE ION
(1)
NA : SODIUM ION
(1)
Function and Biology
EC number / name
(1)
2.3.2.27 : RING-type E3 ubiquitin transferase
(13)
Biological function
(1)
metal ion binding
(2)
Sequence and Structure classification
CATH class
(1)
Mainly Alpha
(7)
CATH topology
(1)
Four Helix Bundle (Hemerythrin (Met), subunit A)
(7)
Pfam accession / name
(3)
PF18386 : ROQ_II
(12)
PF21206 : Roquin_1_2-like_ROQ
(12)
PF14634 : zf-RING_5
(1)
Experimental Information
Diffraction protocol
(2)
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(11)
MAD
(1)
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(1)
Synchrotron
(12)
Diffraction source
(9)
SLS BEAMLINE X06DA
(3)
ESRF BEAMLINE ID23-1
(2)
APS BEAMLINE 19-ID
(1)
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
(1)
BESSY BEAMLINE 14.2
(1)
ESRF BEAMLINE BM14
(1)
ESRF BEAMLINE ID29
(1)
NSLS BEAMLINE X25
(1)
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(1)
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APS
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CYANA
(1)
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(1)
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(1)
NMR Field Strength
400.0 - 500
(1)
500.0 - 600
(1)
600.0 - 700
(1)
700.0 - 800
(1)
800.0 - 900
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
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Entries 1 to 10 of 13
Select all entries on this page
Structure of the ZnF domain from human Roquin-1
Schlundt A, Tants JN
Nucleic Acids Res
(2024)
[PMID: 38953172 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Roquin-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-178321 (Preferred)
search this ID

X-ray structure of Roquin ROQ domain in complex with a Selex-derived hexa-loop RNA motif
Janowski R, Schlundt A, Sattler M, Niessing D
Nat Commun
(2016)
[PMID: 27010430 ]
Source organism: Mus musculus
Assembly composition: RNA/protein complex
Assembly name:
Roquin-1 and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-175773 (Preferred)
search this ID

X-ray structure of Roquin ROQ domain in complex with Ox40 hexa-loop RNA motif
Janowski R, Schlundt A, Sattler M, Niessing D
Nat Commun
(2016)
[PMID: 27010430 ]
Source organism: Mus musculus
Assembly composition: RNA/protein complex
Bound ligands:
GOL
Assembly name:
Roquin-1 and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-175774 (Preferred)
search this ID

X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE2 SL RNA motif
Binas O, Tants J-N, Peter SA, Janowski R, Davydova E, Braun J, Niessing D, Schwalbe H, Weigand JE, Schlundt A
Nucleic Acids Res
(2020)
[PMID: 32491174 ]
Source organism: Mus musculus
Assembly composition: RNA/protein complex
Assembly name:
Roquin-1 and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-175775 (Preferred)
search this ID

Crystal structure of N-terminus of Roquin
Kershaw NJ, Vinuesa CG, Babon JJ
To be published
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Roquin-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-175771 (Preferred)
search this ID

X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE1 SL RNA motif
Binas O, Tants J-N, Peter SA, Janowski R, Davydova E, Braun J, Niessing D, Schwalbe H, Weigand JE, Schlundt A
Nucleic Acids Res
(2020)
[PMID: 32491174 ]
Source organism: Mus musculus
Assembly composition: RNA/protein complex
Assembly name:
Roquin-1 and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-175776 (Preferred)
search this ID

Crystal structure of the ROQ domain of human Roquin in complex with the Hmg19 stem-loop RNA
Tan D, Tong L
Nat Struct Mol Biol
(2014)
[PMID: 25026078 ]
Source organisms: Synthetic construct, Homo sapiens
Assembly composition: RNA/protein complex
Assembly name:
Roquin-1 and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-178323 (Preferred)
search this ID

Crystal structure of the ROQ domain of human Roquin in complex with the TNF23 RNA duplex
Tan D, Tong L
Nat Struct Mol Biol
(2014)
[PMID: 25026078 ]
Source organisms: Synthetic construct, Homo sapiens
Assembly composition: RNA/protein complex
Assembly name:
Roquin-1 and RNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-178322 (Preferred)
search this ID

X-ray structure of the ROQ domain from murine Roquin-1
Janowski R, Schlundt A, Sattler M, Niessing D
Nat Struct Mol Biol
(2014)
[PMID: 25026077 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Bound ligands:
EDO
Assembly name:
Roquin-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-175771 (Preferred)
search this ID

Crystal structure of the ROQ domain of human Roquin
Ose T, Verma A, Cockburn JB, Berrow NS, Alderton D, Stuart D, Owens RJ, Jones EY
Nat Commun
(2015)
[PMID: 25697406 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
IOD
Assembly name:
Roquin-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-178321 (Preferred)
search this ID

Entries 1 to 10 of 13