Uniprot accession / id : Q60603  OR   Uniprot accession / id : O95259
 
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Entry Information
Entry status  (1)
REL
(5)
 
Experimental methods  (1)
X-ray diffraction
(5)
 
Authors  (23)
Morais-Cabral JH
(3)
Cadene M
(2)
Gabant G
(2)
Marques-Carvalho MJ
(2)
Schonherr R
(2)
Schönherr R
(2)
Adaixo R
(1)
Carlson AE
(1)
Castro-Rodrigues AF
(1)
Fernandes AS
(1)
Haitin Y
(1)
Harley CA
(1)
Heinemann SH
(1)
Juan S
(1)
Munoz E
(1)
Muskett FW
(1)
Muñoz E
(1)
Oppermann J
(1)
Sahoo N
(1)
Vieira-Pires RS
(1)
Xiaohong Q
(1)
Xue T
(1)
Zagotta WN
(1)
 
Homo / hetero assembly  (2)
homo
(3)
hetero
(2)
 
Assembly composition  (2)
protein structure
(3)
protein/protein complex
(2)
 
Assembly polymer count  (2)
monomer
(3)
dimer
(2)
 
Resolution distribution
1.5 - 2
(3)
2.0 - 2.5
(1)
2.5 - 3
(1)
 
Release year distribution
2010 - 2015
(3)
2015 - 2020
(2)
 
Journal  (5)
J Mol Biol
(1)
Nature
(1)
PLoS One
(1)
Structure
(1)
To be published
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(5)
 
Organism name  (2)
Mus musculus
(4)
Homo sapiens
(1)
 
Molecule name  (9)
EAG channel 1
(5)
Ether-a-go-go potassium channel 1
(5)
Potassium voltage-gated channel subfamily H member 1
(5)
Voltage-gated delayed rectifier potassium channel KCNH1
(5)
Voltage-gated potassium channel subunit Kv10.1
(5)
m-eag
(4)
mEAG1
(4)
h-eag
(1)
hEAG1
(1)
 
Molecule type  (1)
Protein
(5)
 
Gene names  (5)
Eag1
(4)
Kcnh1
(4)
EAG
(1)
EAG1
(1)
KCNH1
(1)
 
Interacting Molecules  (2)
Calmodulin
(1)
Voltage-gated delayed rectifier potassium channel KCNH1
(1)
 
Interacting ligands  (1)
SO4 : SULFATE ION
(1)
 
Function and Biology
Biological function  (1)
voltage-gated potassium channel activity
(4)
 
Biological process  (1)
potassium ion transport
(4)
 
Biological cell component  (1)
membrane
(4)
 
Sequence and Structure classification
CATH class  (2)
Alpha Beta
(3)
Mainly Beta
(2)
 
CATH topology  (2)
Beta-Lactamase
(3)
Jelly Rolls
(2)
 
Pfam accession / name  (2)
PF13426 : PAS_9
(3)
PF00027 : cNMP_binding
(2)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(5)
 
Diffraction radiation source type  (1)
Synchrotron
(5)
 
Diffraction source  (5)
ALS BEAMLINE 8.2.1
(1)
ESRF BEAMLINE ID14-2
(1)
ESRF BEAMLINE ID14-4
(1)
SOLEIL BEAMLINE PROXIMA 2
(1)
SSRF BEAMLINE BL17U
(1)
 
Synchrotron site  (4)
ESRF
(2)
ALS
(1)
SOLEIL
(1)
SSRF
(1)
 
Diffraction detector type  (1)
CCD
(5)
 
Refinement software  (3)
PHENIX
(4)
CNS
(1)
REFMAC
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 5 of 5
Entries 1 to 5 of 5
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hEAG PAS domain
Xue T, Juan S, Xiaohong Q
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Voltage-gated delayed rectifier potassium channel KCNH1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-131873 (Preferred)   search this ID
PDBe-KB: O95259   
X-ray diffraction
1.9Å resolution
Released: 4 May 2016
Model geometry
Fit model/data
5j7e
5j7e
5j7e
Crystal Structure Analysis of Ca2+-calmodulin and a C-terminal EAG1 channel fragment
Marques-Carvalho MJ, Morais-Cabral JH
Structure (2016) [PMID: 27618660  ]
Assembly composition: protein/protein complex
Bound ligands: CA    CA   
Assembly name: Calmodulin and Voltage-gated delayed rectifier potassium channel KCNH1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-158572 (Preferred)   search this ID
PDBe-KB: Q60603    P62149   
X-ray diffraction
2.85Å resolution
Released: 14 Sep 2016
Model geometry
Fit model/data
5hit
5hit
5hit
Structure of the eag domain-CNBHD complex of the mouse EAG1 channel
Haitin Y, Carlson AE, Zagotta WN
Nature (2013) [PMID: 23975098  ]
Source organism: Mus musculus  
Assembly composition: protein/protein complex
Assembly name: Voltage-gated delayed rectifier potassium channel KCNH1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-178793 (Preferred)   search this ID
PDBe-KB: Q60603   
X-ray diffraction
1.995Å resolution
Released: 28 Aug 2013
Model geometry
Fit model/data
4llo
4llo
4llo
Crystal structure of PAS domain from the mouse EAG1 potassium channel
Adaixo R, Morais-Cabral JH
PLoS One (2013) [PMID: 23555008  ]
Source organism: Mus musculus  
Assembly composition: protein only structure
Bound ligands: SO4   
Assembly name: Voltage-gated delayed rectifier potassium channel KCNH1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-178792 (Preferred)   search this ID
PDBe-KB: Q60603   
X-ray diffraction
1.85Å resolution
Released: 27 Mar 2013
Model geometry
Fit model/data
4hoi
4hoi
4hoi
Cyclic nucleotide binding-homology domain from mouse EAG1 potassium channel
Marques-Carvalho MJ, Sahoo N, Muskett FW, Vieira-Pires RS, Gabant G, Cadene M, Schonherr R, Morais-Cabral JH
J Mol Biol (2012) [PMID: 22732247  ]
Source organism: Mus musculus  
Assembly composition: protein only structure
Assembly name: Voltage-gated delayed rectifier potassium channel KCNH1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-178792 (Preferred)   search this ID
PDBe-KB: Q60603   
X-ray diffraction
2.2Å resolution
Released: 11 Jul 2012
Model geometry
Fit model/data
4f8a
4f8a
4f8a
Entries 1 to 5 of 5
Entries 1 to 5 of 5