Entry status  (1)

REL

(1)

Experimental methods  (1)

X-ray diffraction

(1)

Authors  (10)

Buckle AM

(1)

Coughlin PB

(1)

Hitchen CR

(1)

Horvath AJ

(1)

Kan WT

(1)

Langendorf CG

(1)

Law RH

(1)

Law RHP

(1)

Sofian T

(1)

Whisstock JC

(1)

Homo / hetero assembly  (1)

homo

(1)

Assembly composition  (1)

protein structure

(1)

Assembly polymer count  (1)

monomer

(1)

Resolution distribution

2.5 - 3

(1)

Release year distribution

2005 - 2010

(1)

Journal  (1)

Blood

(1)

Organism superkingdom  (1)

Eukaryota

(1)

Organism name  (1)

Mus musculus

(1)

Molecule name  (5)

Alpha-2-AP

(1)

Alpha-2-PI

(1)

Alpha-2-antiplasmin

(1)

Alpha-2-plasmin inhibitor

(1)

Serpin F2

(1)

Molecule type  (1)

Protein

(1)

Gene names  (2)

Pli

(1)

Serpinf2

(1)

Biological function  (5)

endopeptidase inhibitor activity

(1)

peptidase inhibitor activity

(1)

protease binding

(1)

protein homodimerization activity

(1)

serine-type endopeptidase inhibitor activity

(1)

Biological process  (14)

acute-phase response

(1)

blood vessel morphogenesis

(1)

collagen fibril organization

(1)

maintenance of blood vessel diameter homeostasis by renin-angiotensin

(1)

negative regulation of fibrinolysis

(1)

negative regulation of plasminogen activation

(1)

positive regulation of ERK1 and ERK2 cascade

(1)

positive regulation of JNK cascade

(1)

positive regulation of cell differentiation

(1)

positive regulation of collagen biosynthetic process

(1)

positive regulation of smooth muscle cell proliferation

(1)

positive regulation of stress fiber assembly

(1)

positive regulation of transcription by RNA polymerase II

(1)

positive regulation of transforming growth factor beta production

(1)

Biological cell component  (5)

cell surface

(1)

collagen-containing extracellular matrix

(1)

extracellular region

(1)

extracellular space

(1)

fibrinogen complex

(1)

CATH class  (2)

Alpha Beta

(1)

Mainly Beta

(1)

CATH topology  (2)

Alpha-1-antitrypsin; domain 1

(1)

Antithrombin; Chain I, domain 2

(1)

Pfam accession / name  (1)

PF00079 : Serpin

(1)

Diffraction protocol  (1)

Single wavelength

(1)

Diffraction radiation source type  (1)

Rotating anode

(1)

Diffraction source  (1)

RIGAKU RU300

(1)

Diffraction detector type  (1)

Image plate

(1)

Refinement software  (1)

REFMAC

(1)

Representative Structures

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