Entry status  (1)

REL

(21)

Experimental methods  (3)

X-ray diffraction

(17)

Electron Microscopy

(3)

Solution NMR

(1)

Authors  (144)

Jura N

(8)

Shan Y

(5)

Shaw DE

(5)

Littlefield P

(4)

Agard DA

(3)

Diwanji D

(3)

Liu L

(3)

Mysore V

(3)

Thaker TM

(3)

Trenker R

(3)

Verba KA

(3)

Wang F

(3)

Cho HS

(2)

De Nardis C

(2)

Gallenne T

(2)

Geuijen CAW

(2)

Gros P

(2)

Hendriks LJA

(2)

Logtenberg T

(2)

Maussang D

(2)

Mittl PRE

(2)

Nijhuis R

(2)

Pluckthun A

(2)

Plückthun A

(2)

Radom F

(2)

Rovers E

(2)

Throsby M

(2)

Visser T

(2)

Vonrhein C

(2)

de Kruif J

(2)

Agnew C

(1)

Alvarado D

(1)

Amick JR

(1)

Arseniev AS

(1)

Arteaga CL

(1)

Ayaz P

(1)

Bae D

(1)

Bialucha CU

(1)

Bossenmaier B

(1)

Bostrom J

(1)

Campbell MR

(1)

Cao X

(1)

Cha JS

(1)

Chen D

(1)

Chen Y

(1)

Cho H-S

(1)

Choi MK

(1)

Clark R

(1)

Crocker LM

(1)

Danilenko DM

(1)

Das R

(1)

Dimoudis N

(1)

Dolgikh DA

(1)

Dowbenko D

(1)

Eigenbrot C

(1)

Elis W

(1)

Ettenberg SA

(1)

Fields C

(1)

Franke Y

(1)

Friess T

(1)

Fuh G

(1)

Garfinkle S

(1)

Garner AP

(1)

Garrett JT

(1)

Gerdes CA

(1)

Greenlee EB

(1)

Gu J

(1)

Haber L

(1)

Haberl M

(1)

Hadari Y

(1)

Haubst N

(1)

Heidt AB

(1)

Herlihy K

(1)

Hoelzlwimmer G

(1)

Hong M

(1)

Hong SB

(1)

Hopfner KP

(1)

Huang A

(1)

Hwang J

(1)

Kato K

(1)

Khabibullina NF

(1)

Kim JY

(1)

Kim K

(1)

Kim M

(1)

Kim U

(1)

Kirpichnikov MP

(1)

Kolm I

(1)

Kunz C

(1)

Kuriyan J

(1)

Leahy DJ

(1)

Lee CV

(1)

Lee S

(1)

Lemmon MA

(1)

Lewis Phillips GD

(1)

Li S

(1)

Liang J

(1)

Lifke V

(1)

Ligon GF

(1)

Lillquist JS

(1)

Liu Y

(1)

 

More...

Homo / hetero assembly  (2)

hetero

(15)

homo

(6)

Assembly composition  (2)

protein/protein complex

(15)

protein structure

(6)

Assembly polymer count  (4)

trimer

(9)

dimer

(8)

monomer

(3)

pentamer

(1)

Resolution distribution

1.5 - 2

(1)

2.0 - 2.5

(2)

2.5 - 3

(8)

3.0 - 3.5

(7)

3.5 - 4

(1)

4.0 - 4.5

(1)

Release year distribution

2000 - 2005

(1)

2005 - 2010

(2)

2010 - 2015

(9)

2015 - 2020

(5)

2020 - 2025

(7)

Journal  (11)

Cancer Cell

(3)

Nature

(3)

Proc Natl Acad Sci U S A

(3)

Sci Signal

(3)

Acta Crystallogr F Struct Biol Commun

(2)

Cancer Res

(2)

Biochim Biophys Acta

(1)

Cell Rep

(1)

Mol Cancer Ther

(1)

Science

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(21)

Organism name  (1)

Homo sapiens

(21)

Molecule name  (3)

Proto-oncogene-like protein c-ErbB-3

(21)

Receptor tyrosine-protein kinase erbB-3

(21)

Tyrosine kinase-type cell surface receptor HER3

(21)

Molecule type  (1)

Protein

(21)

Gene names  (2)

ERBB3

(21)

HER3

(21)

Interacting Molecules  (19)

Epidermal growth factor receptor

(3)

Maltose/maltodextrin-binding periplasmic protein

(3)

Neuregulin-1

(3)

Receptor tyrosine-protein kinase erbB-2

(3)

DARPin_D5

(2)

MF3178 FAB heavy chain

(2)

MF3178 FAB light chain

(2)

Anti-ErbB3 Fab heavy chain

(1)

Anti-ErbB3 Fab light chain

(1)

Fab DL11 heavy chain

(1)

Fab DL11 light chain

(1)

Fab LC region of KTN3379

(1)

Ig-like domain-containing protein

(1)

MOR09825 Fab fragment heavy chain

(1)

MOR09825 Fab fragment light chain

(1)

RG7116 Fab heavy chain

(1)

RG7116 Fab light chain

(1)

Trastuzumab Fab Heavy Chain

(1)

Trastuzumab Fab Light Chain

(1)

Interacting ligands  (7)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(12)

ANP : PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER

(5)

MG : MAGNESIUM ION

(5)

ACT : ACETATE ION

(2)

BMA : beta-D-mannopyranose

(1)

DB8 : 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile

(1)

SO4 : SULFATE ION

(1)

EC number / name  (1)

2.7.10.1 : Receptor protein-tyrosine kinase

(21)

Biological function  (3)

ATP binding

(9)

protein kinase activity

(9)

protein tyrosine kinase activity

(3)

Biological process  (2)

protein phosphorylation

(9)

cell surface receptor protein tyrosine kinase signaling pathway

(3)

Biological cell component  (1)

membrane

(3)

SCOP fold  (2)

Knottins (small inhibitors, toxins, lectins)

(1)

Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)

(1)

SCOP family  (2)

Growth factor receptor domain

(1)

L domain

(1)

CATH class  (3)

Alpha Beta

(10)

Mainly Alpha

(6)

Mainly Beta

(5)

CATH topology  (5)

24 nucleotide stem-loop, u2 snrnp hairpin iv. U2 a'; Chain A

(5)

Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2

(5)

Phosphorylase Kinase; domain 1

(5)

Transferase(Phosphotransferase); domain 1

(5)

cAMP-dependent Protein Kinase, Chain A

(1)

Pfam accession / name  (4)

PF01030 : Recep_L_domain

(12)

PF14843 : GF_recep_IV

(12)

PF00757 : Furin-like

(11)

PF07714 : PK_Tyr_Ser-Thr

(9)

Diffraction protocol  (2)

Single wavelength

(16)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(17)

Diffraction source  (13)

ALS BEAMLINE 8.3.1

(4)

SLS BEAMLINE X06SA

(2)

ALS BEAMLINE 5.0.2

(1)

ALS BEAMLINE 8.2.1

(1)

APS BEAMLINE 17-ID

(1)

APS BEAMLINE 23-ID-B

(1)

APS BEAMLINE 24-ID-E

(1)

ESRF BEAMLINE ID23-1

(1)

ESRF BEAMLINE ID23-2

(1)

ESRF BEAMLINE MASSIF-3

(1)

NSLS BEAMLINE X4A

(1)

PAL/PLS BEAMLINE 11C

(1)

SPRING-8 BEAMLINE BL38B1

(1)

Synchrotron site  (7)

ALS

(6)

APS

(3)

ESRF

(3)

SLS

(2)

NSLS

(1)

PAL/PLS

(1)

SPring-8

(1)

Diffraction detector type  (2)

CCD

(11)

Pixel

(6)

Representative Structures

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