Entry status  (1)

REL

(14)

Experimental methods  (3)

X-ray diffraction

(8)

Electron Microscopy

(4)

Solution NMR

(2)

Authors  (68)

Leahy DJ

(7)

Bingham T

(4)

Diwanji D

(4)

Jura N

(4)

Trenker R

(4)

Verba KA

(4)

Banjade S

(3)

Bornmann WG

(3)

Bose R

(3)

Bouyain S

(3)

Choi SH

(3)

Cole PA

(3)

Lemmon MA

(3)

Liu P

(3)

Pal A

(3)

Qiu C

(3)

Sathyamurthy A

(3)

Tarrant MK

(3)

Arseniev AS

(2)

Bocharov EV

(2)

Goncharuk MV

(2)

Longo PA

(2)

Mineev KS

(2)

Brashear RL

(1)

Brignola P

(1)

Byrne PO

(1)

Caferro TR

(1)

Cleveland IV TE

(1)

Cleveland TE

(1)

Deraedt K

(1)

Dickerson SH

(1)

Dickson HD

(1)

Donaldson KH

(1)

Eigenbrot C

(1)

Elenius K

(1)

Elgenbrot C

(1)

Ellis B

(1)

Ferguson KM

(1)

Gaul M

(1)

Griffin RJ

(1)

Hassell AM

(1)

Hollmen M

(1)

Hollmén M

(1)

Joensuu H

(1)

Keith B

(1)

Kurppa K

(1)

Li S

(1)

Mullin R

(1)

Petrov KG

(1)

Reinvall I

(1)

Reno MJ

(1)

Rusnak DW

(1)

Schoffski P

(1)

Schöffski P

(1)

Shewchuk LM

(1)

Smeets A

(1)

Tadepalli SM

(1)

Uehling DE

(1)

Ulrich JC

(1)

Vahlberg T

(1)

Vanderwall DE

(1)

Vandorpe T

(1)

Wagner CD

(1)

Waterson AG

(1)

White WL

(1)

Wildiers H

(1)

Williams JD

(1)

Wood ER

(1)

Homo / hetero assembly  (2)

homo

(8)

hetero

(5)

Assembly composition  (2)

protein structure

(8)

protein/protein complex

(5)

Assembly polymer count  (4)

monomer

(6)

dimer

(3)

tetramer

(2)

trimer

(2)

Resolution distribution

2.0 - 2.5

(3)

2.5 - 3

(2)

3.0 - 3.5

(4)

3.5 - 4

(2)

4.0 - 4.5

(1)

Release year distribution

2000 - 2005

(1)

2005 - 2010

(5)

2010 - 2015

(5)

2020 - 2025

(4)

Journal  (6)

Elife

(4)

Proc Natl Acad Sci U S A

(3)

Structure

(3)

Biochim Biophys Acta

(2)

PLoS One

(1)

Protein Sci

(1)

Organism superkingdom  (1)

Eukaryota

(14)

Organism name  (1)

Homo sapiens

(14)

Molecule name  (8)

4ICD

(14)

E4ICD

(14)

ERBB4 intracellular domain

(14)

Proto-oncogene-like protein c-ErbB-4

(14)

Receptor tyrosine-protein kinase erbB-4

(14)

Tyrosine kinase-type cell surface receptor HER4

(14)

p180erbB4

(14)

s80HER4

(14)

Molecule type  (1)

Protein

(14)

Gene names  (2)

ERBB4

(14)

HER4

(14)

Interacting Molecules  (3)

Neuregulin-1

(3)

Betacellulin

(2)

Receptor tyrosine-protein kinase erbB-2

(2)

Interacting ligands  (9)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(7)

BMA : beta-D-mannopyranose

(4)

MAN : alpha-D-mannopyranose

(4)

FMM : N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE

(1)

GW7 : N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-ethylthieno[3,2-d]pyrimidin-4-amine

(1)

PEG : DI(HYDROXYETHYL)ETHER

(1)

PG4 : TETRAETHYLENE GLYCOL

(1)

SO4 : SULFATE ION

(1)

YT3 : YTTRIUM (III) ION

(1)

EC number / name  (1)

2.7.10.1 : Receptor protein-tyrosine kinase

(14)

Biological function  (3)

ATP binding

(4)

protein kinase activity

(4)

protein tyrosine kinase activity

(4)

Biological process  (1)

protein phosphorylation

(4)

CATH class  (4)

Alpha Beta

(8)

Mainly Alpha

(4)

Mainly Beta

(4)

Special

(1)

CATH topology  (5)

24 nucleotide stem-loop, u2 snrnp hairpin iv. U2 a'; Chain A

(4)

Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2

(4)

Phosphorylase Kinase; domain 1

(4)

Transferase(Phosphotransferase); domain 1

(4)

Single alpha-helices involved in coiled-coils or other helix-helix interfaces

(1)

Pfam accession / name  (5)

PF00757 : Furin-like

(8)

PF01030 : Recep_L_domain

(8)

PF14843 : GF_recep_IV

(7)

PF07714 : PK_Tyr_Ser-Thr

(4)

PF21314 : TM_ErbB1

(2)

Representative Structures

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