Uniprot accession / id : Q67FY2  OR   Uniprot accession / id : Q86UU0
 
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Entry Information
Entry status  (1)
REL
(3)
 
Experimental methods  (1)
X-ray diffraction
(3)
 
Authors  (8)
Bienz M
(3)
Fiedler M
(3)
Miller TC
(3)
Rutherford TJ
(3)
Birchall K
(2)
Chugh J
(2)
Miller TCR
(2)
Johnson CM
(1)
 
Homo / hetero assembly  (2)
homo
(2)
hetero
(1)
 
Assembly composition  (2)
protein structure
(2)
protein/protein complex
(1)
 
Assembly polymer count  (2)
monomer
(2)
dimer
(1)
 
Resolution distribution
1.0 - 1.5
(1)
1.5 - 2
(2)
 
Release year distribution
2005 - 2010
(1)
2010 - 2015
(3)
 
Journal  (2)
ACS Chem Biol
(2)
J Mol Biol
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(3)
 
Organism name  (1)
Homo sapiens
(3)
 
Molecule name  (5)
B-cell CLL/lymphoma 9-like protein
(3)
B-cell lymphoma 9-like protein
(3)
BCL9-like protein
(3)
Protein BCL9-2
(3)
Pygopus homolog 2
(3)
 
Molecule type  (1)
Protein
(3)
 
Gene names  (4)
BCL9L
(3)
DLNB11
(3)
PP7910
(3)
PYGO2
(3)
 
Interacting Molecules  (1)
Histone H3.1
(1)
 
Interacting ligands  (4)
ZN : ZINC ION
(3)
94W : 6-methoxy-1,3-benzothiazol-2-amine
(1)
GOL : GLYCEROL
(1)
PEG : DI(HYDROXYETHYL)ETHER
(1)
 
Sequence and Structure classification
CATH class  (1)
Alpha Beta
(3)
 
CATH topology  (1)
Herpes Virus-1
(3)
 
Pfam accession / name  (1)
PF00628 : PHD
(3)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(3)
 
Diffraction radiation source type  (1)
Synchrotron
(3)
 
Diffraction source  (2)
ESRF BEAMLINE ID29
(2)
DIAMOND BEAMLINE I04
(1)
 
Synchrotron site  (2)
ESRF
(2)
Diamond
(1)
 
Diffraction detector type  (2)
Pixel
(2)
CCD
(1)
 
Refinement software  (1)
REFMAC
(3)
 
Representative Structures
Representative Structures
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Entries 1 to 3 of 3
Entries 1 to 3 of 3
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Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain
Miller TC, Rutherford TJ, Johnson CM, Fiedler M, Bienz M
J Mol Biol (2010) [PMID: 20637214  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: PEG    GOL    PEG    ZN    ZN   
Assembly name: B-cell CLL/lymphoma 9-like protein, Pygopus homolog 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-183189 (Preferred)   search this ID
PDBe-KB: Q9BRQ0    Q86UU0   
X-ray diffraction
1.9Å resolution
Released: 28 Jul 2010
Model geometry
Fit model/data
2xb1
2xb1
2xb1
Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment
Miller TCR, Fiedler M, Rutherford TJ, Birchall K, Chugh J, Bienz M
ACS Chem Biol (2014) [PMID: 25323450  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: ZN    ZN    94W   
Assembly name: B-cell CLL/lymphoma 9-like protein, Pygopus homolog 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-183189 (Preferred)   search this ID
PDBe-KB: Q9BRQ0    Q86UU0   
X-ray diffraction
1.65Å resolution
Released: 5 Nov 2014
Model geometry
Fit model/data
4up5
4up5
4up5
Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide
Miller TCR, Fiedler M, Rutherford TJ, Birchall K, Chugh J, Bienz M
ACS Chem Biol (2014) [PMID: 25323450  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: ZN    ZN   
Modified residues: ALY    MLY    MLY    ALY   
Assembly name: Histone H3.1 and B-cell CLL/lymphoma 9-like protein, Pygopus homolog 2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-159418 (Preferred)   search this ID
PDBe-KB: Q9BRQ0    Q86UU0    P68431   
X-ray diffraction
1.28Å resolution
Released: 5 Nov 2014
Model geometry
Fit model/data
4up0
4up0
4up0
Entries 1 to 3 of 3
Entries 1 to 3 of 3