Entry status  (1)

REL

(8)

Experimental methods  (2)

X-ray diffraction

(7)

Electron Microscopy

(1)

Authors  (44)

Hockla A

(3)

Radisky ES

(3)

Soares AS

(3)

Alloy A

(2)

Alloy AP

(2)

Delcea M

(2)

Geist N

(2)

Girbardt B

(2)

Kayode O

(2)

Lammers M

(2)

Lerch MM

(2)

Mayerle J

(2)

McDonnell TCR

(2)

Nagel F

(2)

Palm GJ

(2)

Susemihl A

(2)

Wang R

(2)

Bode W

(1)

Cui F

(1)

Ding Z

(1)

Ding ZY

(1)

Engh RA

(1)

Fontecilla-Camps JC

(1)

Forest E

(1)

Gaboriaud C

(1)

Guy-Crotte O

(1)

Hopfner KP

(1)

Huang H

(1)

Huang HJ

(1)

Huber R

(1)

Kopetzki E

(1)

Kresse G-B

(1)

Kresse GB

(1)

Li K

(1)

Li S

(1)

Li Z

(1)

Peng L

(1)

Salameh MA

(1)

Serre L

(1)

Song Q

(1)

Xia C

(1)

Yang X

(1)

Yin H

(1)

Zhang D

(1)

Homo / hetero assembly  (2)

hetero

(6)

homo

(2)

Assembly composition  (2)

protein/protein complex

(6)

protein structure

(2)

Assembly polymer count  (3)

dimer

(6)

tetramer

(1)

trimer

(1)

Resolution distribution

1.0 - 1.5

(1)

1.5 - 2

(1)

2.0 - 2.5

(4)

2.5 - 3

(1)

4.5 - 5

(1)

Release year distribution

1990 - 1995

(1)

1995 - 2000

(2)

2005 - 2010

(1)

2010 - 2015

(2)

2015 - 2020

(2)

2020 - 2025

(3)

Journal  (5)

J Biol Chem

(3)

Int J Mol Sci

(2)

J Mol Biol

(1)

Nat Commun

(1)

Proc Natl Acad Sci U S A

(1)

Organism superkingdom  (1)

Eukaryota

(8)

Organism name  (1)

Homo sapiens

(8)

Molecule name  (10)

Alpha-trypsin chain 1

(8)

Alpha-trypsin chain 2

(8)

Anionic trypsin I

(8)

Anionic trypsin-I

(8)

Beta-trypsin

(8)

Cationic trypsinogen

(8)

Pretrypsinogen I

(8)

Serine protease 1

(8)

Trypsin I

(8)

Trypsin-1

(8)

Molecule type  (1)

Protein

(8)

Gene names  (4)

PRSS1

(8)

TRP1

(8)

TRY1

(8)

TRYP1

(8)

Interacting Molecules  (4)

Pancreatic trypsin inhibitor

(3)

Serine protease inhibitor Kazal-type 1

(2)

Enteropeptidase catalytic light chain

(1)

Enteropeptidase non-catalytic heavy chain

(1)

Interacting ligands  (4)

SO4 : SULFATE ION

(4)

CA : CALCIUM ION

(3)

0G6 : D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide

(1)

ISP : PHOSPHORYLISOPROPANE

(1)

EC number / name  (1)

3.4.21.4 : Trypsin

(8)

Biological function  (5)

serine-type endopeptidase activity

(8)

hydrolase activity

(7)

metal ion binding

(7)

peptidase activity

(7)

serine-type peptidase activity

(7)

Biological process  (3)

proteolysis

(8)

digestion

(7)

extracellular matrix disassembly

(7)

Biological cell component  (4)

blood microparticle

(7)

collagen-containing extracellular matrix

(7)

extracellular region

(7)

extracellular space

(7)

SCOP fold  (1)

Trypsin-like serine proteases

(2)

SCOP family  (1)

Eukaryotic proteases

(2)

CATH class  (1)

Mainly Beta

(5)

CATH topology  (1)

Thrombin, subunit H

(5)

Pfam accession / name  (1)

PF00089 : Trypsin

(8)

Diffraction protocol  (1)

Single wavelength

(5)

Diffraction radiation source type  (2)

Synchrotron

(6)

Rotating anode

(1)

Diffraction source  (6)

NSLS BEAMLINE X29A

(2)

BESSY BEAMLINE 14.1

(1)

BESSY BEAMLINE 14.2

(1)

LURE BEAMLINE DW32

(1)

NSLS BEAMLINE X12B

(1)

RIGAKU RUH2R

(1)

Synchrotron site  (3)

NSLS

(3)

BESSY

(2)

LURE

(1)

Diffraction detector type  (3)

CCD

(3)

Image plate

(2)

Pixel

(2)

Refinement software  (3)

PHENIX

(3)

REFMAC

(3)

X-PLOR

(2)

EM microscope model  (1)

FEI TITAN KRIOS

(1)

EM detector name  (1)

GATAN K2 SUMMIT (4k x 4k)

(1)

Representative Structures

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