Entry status  (1)

REL

(11)

Experimental methods  (1)

X-ray diffraction

(11)

Authors  (28)

Schellenberg MJ

(10)

Tumbale P

(10)

Williams RS

(10)

Tumbale PS

(9)

Fairweather E

(6)

Krahn J

(6)

Little JN

(6)

London RE

(6)

Mueller GA

(6)

Waddell I

(6)

Watson M

(6)

Kunkel TA

(4)

Williams JS

(4)

Becherel OJ

(1)

Chen J

(1)

Cherry AL

(1)

Epe B

(1)

Fusser M

(1)

Gueven N

(1)

Jakob B

(1)

Katyal S

(1)

Kijas AW

(1)

Lavin MF

(1)

McKinnon PJ

(1)

Peng C

(1)

Smerdon SJ

(1)

Taucher-Scholz G

(1)

Tumbale PP

(1)

Homo / hetero assembly  (2)

hetero

(10)

homo

(1)

Assembly composition  (3)

DNA/DNA/RNA hybrid/protein complex

(8)

DNA/protein complex

(2)

protein structure

(1)

Assembly polymer count  (3)

trimer

(9)

hexamer

(1)

monomer

(1)

Resolution distribution

1.5 - 2

(7)

2.0 - 2.5

(2)

2.5 - 3

(2)

Release year distribution

2005 - 2010

(1)

2010 - 2015

(5)

2015 - 2020

(6)

Journal  (3)

EMBO J

(6)

Nature

(4)

Nucleic Acids Res

(1)

Organism superkingdom  (1)

Eukaryota

(11)

Organism name  (1)

Homo sapiens

(11)

Molecule name  (3)

Aprataxin

(11)

FHA-HIT

(11)

Forkhead-associated domain histidine triad-like protein

(11)

Molecule type  (1)

Protein

(11)

Gene names  (2)

APTX

(11)

AXA1

(11)

Interacting Molecules  (8)

DNA (5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3')

(4)

DNA/RNA (5'-R(P*G)-D(P*TP*TP*AP*TP*GP*AP*TP*TP*C)-3')

(4)

5'-D(*GP*AP*AP*TP*CP*AP*TP*AP*AP*C)-3'

(3)

5'-R(P*G)-D(P*TP*TP*AP*TP*GP*AP*TP*TP*C)-3'

(3)

5'-D(P*GP*TP*TP*CP*TP*AP*GP*AP*AP*C)-3'

(1)

DNA (5'-D(*AP*AP*CP*AP*GP*C)-3')

(1)

DNA (5'-D(P*GP*TP*TP*CP*TP*AP*GP*AP*AP*C)-3')

(1)

DNA/RNA (5'-R(P*G)-D(P*TP*TP*CP*TP*AP*TP*AP*TP*AP*TP*AP*GP*AP*AP*CP*GP*CP*TP*GP*TP*T)-3')

(1)

Interacting ligands  (6)

ZN : ZINC ION

(10)

AMP : ADENOSINE MONOPHOSPHATE

(9)

BME : BETA-MERCAPTOETHANOL

(5)

NA : SODIUM ION

(4)

GOL : GLYCEROL

(2)

V5A : adenosine-5'-vanadate

(1)

EC number / name  (2)

3.6.1.71 : Adenosine-5'-diphospho-5'-(DNA) diphosphatase

(11)

3.6.1.72 : DNA-3'-diphospho-5'-guanosine diphosphatase

(11)

Biological function  (1)

catalytic activity

(10)

CATH class  (2)

Alpha Beta

(10)

Mainly Beta

(1)

CATH topology  (2)

HIT family, subunit A

(10)

Tumour Suppressor Smad4

(1)

Pfam accession / name  (3)

PF11969 : DcpS_C

(10)

PF16278 : zf-C2HE

(10)

PF17913 : FHA_2

(1)

Diffraction protocol  (1)

Single wavelength

(11)

Diffraction radiation source type  (2)

Synchrotron

(10)

Rotating anode

(1)

Diffraction source  (2)

APS BEAMLINE 22-ID

(10)

RIGAKU

(1)

Synchrotron site  (1)

APS

(10)

Diffraction detector type  (2)

CCD

(10)

Image plate

(1)

Refinement software  (2)

PHENIX

(10)

REFMAC

(1)

Representative Structures

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