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(1)
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(1)
X-ray diffraction
(10)
Authors
(17)
Fass D
(10)
Alon A
(7)
Grossman I
(7)
Ilani T
(5)
Thorpe C
(5)
Baker D
(3)
DiMaio F
(3)
Fleishman SJ
(3)
Gat Y
(3)
Haran G
(3)
Kodali VK
(3)
Mehlman T
(3)
Heckler EJ
(2)
Grossman-Haham I
(1)
Javitt G
(1)
Mutsafi Y
(1)
Resnick E
(1)
Homo / hetero assembly
(2)
homo
(6)
hetero
(4)
Assembly composition
(2)
protein structure
(6)
protein/protein complex
(4)
Assembly polymer count
(3)
monomer
(6)
trimer
(3)
hexamer
(1)
Resolution distribution
1.5 - 2
(2)
2.0 - 2.5
(6)
2.5 - 3
(2)
Release year distribution
2005 - 2010
(2)
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(6)
2015 - 2020
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Nature
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Protein Eng Des Sel
(3)
FEBS Lett
(2)
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(1)
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Macromolecules
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(1)
Eukaryota
(10)
Organism name
(2)
Mus musculus
(6)
Homo sapiens
(4)
Molecule name
(5)
Quiescin Q6
(10)
Sulfhydryl oxidase 1
(10)
Skin sulfhydryl oxidase
(6)
mSOx
(6)
hQSOX
(4)
Molecule type
(1)
Protein
(10)
Gene names
(6)
Qscn6
(6)
Qsox1
(6)
Sox
(6)
QSCN6
(4)
QSOX1
(4)
UNQ2520/PRO6013
(4)
Interacting Molecules
(8)
Fab 316 heavy chain
(1)
Fab 316 light chain
(1)
Heavy Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody
(1)
Heavy chain of FAB fragment
(1)
Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1
(1)
Light Chain of Fab Fragment from a Mouse QSOX1-Specific Antibody
(1)
Light chain of FAB fragment
(1)
Light chain of Fab fragment from an antibody targeting mouse and human QSOX1
(1)
Interacting ligands
(4)
FAD : FLAVIN-ADENINE DINUCLEOTIDE
(4)
FLC : CITRATE ANION
(1)
PO4 : PHOSPHATE ION
(1)
SO4 : SULFATE ION
(1)
Function and Biology
EC number / name
(1)
1.8.3.2 : Thiol oxidase
(10)
Biological function
(2)
flavin-dependent sulfhydryl oxidase activity
(10)
thiol oxidase activity
(4)
Compound cofactor class
(1)
Flavin adenine dinucleotide
(4)
Sequence and Structure classification
CATH class
(2)
Alpha Beta
(7)
Mainly Alpha
(3)
CATH topology
(2)
Glutaredoxin
(7)
Four Helix Bundle (Hemerythrin (Met), subunit A)
(3)
Pfam accession / name
(4)
PF00085 : Thioredoxin
(8)
PF18108 : QSOX_Trx1
(8)
PF04777 : Evr1_Alr
(4)
PF18371 : FAD_SOX
(4)
Experimental Information
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(10)
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(8)
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RIGAKU RUH3R
(8)
ESRF BEAMLINE ID23-1
(1)
ESRF BEAMLINE ID29
(1)
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(1)
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PHENIX
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Representative Structures
Representative Structures
Entries
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Entries 1 to 10 of 10
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Sulfhydryl Oxidase Fragment of Human QSOX1
Alon A, Fass D
FEBS Lett
(2010)
[PMID: 20211621 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Sulfhydryl oxidase 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-126252 (Preferred)
search this ID

C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
Fass D, Alon A, Gat Y
Nature
(2012)
[PMID: 22801504 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Sulfhydryl oxidase 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-183891 (Preferred)
search this ID

C76A/C455S mutant of mouse QSOX1 containing an interdomain disulfide
Fass D, Alon A, Gat Y
Nature
(2012)
[PMID: 22801504 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Sulfhydryl oxidase 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-183891 (Preferred)
search this ID

Oxidoreductase Fragment of Human QSOX1 in Complex with a FAB Fragment from an Anti- Human QSOX1 Antibody
Fass D, Grossman I
J Mol Biol
(2013)
[PMID: 23867277 ]
Source organisms: Mus musculus , Homo sapiens
Assembly composition: protein/protein complex
Bound ligands:
PO4
Assembly name:
Sulfhydryl oxidase 1 and IG-light kappa chain and IG-heavy chain
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-234975 (Preferred)
search this ID

Mutant oxidoreductase fragment of mouse QSOX1 in complex with an antibody Fab
Grossman-Haham I, Fass D
Protein Sci
(2019)
[PMID: 30367560 ]
Source organism: Mus musculus
Assembly composition: protein/protein complex
Assembly name:
Sulfhydryl oxidase 1 and IG-heavy chain and IG-light kappa chain and IG-heavy chain
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-212569 (Preferred)
search this ID

Engineering the Species-Specificity of an Inhibitory Antibody Targeting a Modulator of Tumor Stroma
Grossman I, Fass D
Protein Eng Des Sel
(2016)
[PMID: 26819240 ]
Source organism: Mus musculus
Assembly composition: protein only structure
Assembly name:
Sulfhydryl oxidase 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-183891 (Preferred)
search this ID

Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1
Fass D, Grossman I
Protein Eng Des Sel
(2016)
[PMID: 26819240 ]
Source organism: Mus musculus
Assembly composition: protein/protein complex
Assembly name:
Sulfhydryl oxidase 1 and IG-light kappa chain and IG-heavy chain
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-212568 (Preferred)
search this ID

Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody
Grossman I, Fass D
Protein Eng Des Sel
(2016)
[PMID: 26819240 ]
Source organism: Mus musculus
Assembly composition: protein/protein complex
Assembly name:
Sulfhydryl oxidase 1 and IG-heavy chain and IG-light kappa chain
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-212567 (Preferred)
search this ID

Sulfhydryl Oxidase Fragment of Human QSOX1
Alon A, Fass D
FEBS Lett
(2010)
[PMID: 20211621 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Sulfhydryl oxidase 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-126252 (Preferred)
search this ID

Oxidoreductase Fragment of Human QSOX1
Fass D, Alon A
Nature
(2012)
[PMID: 22801504 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
SO4
Assembly name:
Sulfhydryl oxidase 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-126252 (Preferred)
search this ID

Entries 1 to 10 of 10