Entry status  (1)

REL

(14)

Experimental methods  (2)

Electron Microscopy

(10)

X-ray diffraction

(4)

Authors  (142)

Shukla AK

(4)

Baruah M

(3)

Grzesiek S

(3)

Isaikina P

(3)

Jakob RP

(3)

Maier T

(3)

Panwalkar V

(3)

Petrovic I

(3)

Ranjan A

(3)

Sarma P

(3)

Bous J

(2)

Bron P

(2)

Chang S

(2)

Cong X

(2)

Du M

(2)

Fontanel S

(2)

Fouillen A

(2)

Granier S

(2)

Jia N

(2)

Lai-Kee-Him J

(2)

Liu N

(2)

Lu X

(2)

Lu Y

(2)

Mouillac B

(2)

Orcel H

(2)

Robertson MJ

(2)

Saint-Paul J

(2)

Shen Y

(2)

Shen YQ

(2)

Sibille N

(2)

Skiniotis G

(2)

Sounier R

(2)

Trapani S

(2)

Urbach S

(2)

Wen T

(2)

Wen TL

(2)

Yang X

(2)

Zhang X

(2)

Barros-Alvarez X

(1)

Barros-Álvarez X

(1)

Benmerah A

(1)

Burtey A

(1)

Cai H

(1)

Cao C

(1)

Chaturvedi M

(1)

Chen K

(1)

Chen N

(1)

Chu X

(1)

Cong Y

(1)

Damgen MA

(1)

Dror RO

(1)

Dwivedi-Agnihotri H

(1)

Dämgen MA

(1)

Edward Zhou X

(1)

Edwards PC

(1)

Eric Xu H

(1)

Fan Z

(1)

Fay JF

(1)

Ford MG

(1)

Ford MGJ

(1)

Gao J

(1)

Gao X

(1)

Garcia-Nafria J

(1)

García-Nafría J

(1)

Glenn JS

(1)

Gumpper RH

(1)

Han S

(1)

He Y

(1)

Hua T

(1)

Huang W

(1)

Huttenhain R

(1)

Hüttenhain R

(1)

Inoue A

(1)

Janetzko J

(1)

Jiang L

(1)

Jiang Y

(1)

Jin M

(1)

Kato HE

(1)

Kim K

(1)

Kobilka BK

(1)

Krogan NJ

(1)

Krumm BE

(1)

Lee Y

(1)

Leslie AGW

(1)

Li F

(1)

Li Z

(1)

Lin S

(1)

Liu J

(1)

Liu Y

(1)

Liu ZJ

(1)

Ma L

(1)

Masureel M

(1)

McMahon HT

(1)

Mcmahon HT

(1)

Melcher K

(1)

Mills IG

(1)

Nehme R

(1)

Nehmé R

(1)

Nguyen KC

(1)

Nichols DE

(1)

 

More...

Homo / hetero assembly  (2)

hetero

(13)

homo

(1)

Assembly composition  (2)

protein/protein complex

(13)

protein structure

(1)

Assembly polymer count  (5)

tetramer

(7)

hexamer

(3)

trimer

(2)

monomer

(1)

pentamer

(1)

Resolution distribution

2.0 - 2.5

(1)

2.5 - 3

(1)

3.0 - 3.5

(5)

3.5 - 4

(3)

4.0 - 4.5

(2)

4.5 - 5

(2)

Release year distribution

2005 - 2010

(1)

2015 - 2020

(3)

2020 - 2025

(12)

2025 - 2030

(2)

Journal  (8)

Mol Cell

(3)

Nature

(3)

Nat Chem Biol

(2)

Sci Adv

(2)

Cell Res

(1)

Neuron

(1)

PLoS Biol

(1)

Protein Cell

(1)

Organism superkingdom  (1)

Eukaryota

(14)

Organism name  (1)

Homo sapiens

(14)

Molecule name  (5)

Arrestin beta-1

(14)

Beta-arrestin-1

(14)

Non-visual arrestin-2

(14)

IG-heavy chain

(1)

IG-light kappa chain

(1)

Molecule type  (1)

Protein

(14)

Gene names  (2)

ARR1

(14)

ARRB1

(14)

Interacting Molecules  (25)

Fab30 heavy chain

(5)

Fab30 light chain

(5)

Vasopressin V2 receptor

(4)

C-C chemokine receptor type 5

(2)

Metabotropic glutamate receptor 3

(2)

Neurotensin receptor type 1

(2)

ScFv30

(2)

scFv30

(2)

5-hydroxytryptamine receptor 2B

(1)

AP-2 complex subunit beta

(1)

Activation peptide

(1)

Anti-5HT2BR Fab heavy chain

(1)

Anti-5HT2BR Fab light chain

(1)

Arg-vasopressin

(1)

Beta-1 adrenergic receptor

(1)

Cannabinoid receptor 1

(1)

Glucagon

(1)

Glucagon receptor

(1)

Hemagglutinin

(1)

Nanobody 32

(1)

Neurotensin

(1)

Neurotensin peptide

(1)

Soluble cytochrome b562

(1)

scfv30 light chain, scfv30 heavy chain

(1)

unidentified peptide

(1)

Interacting ligands  (1)

PIO : [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate

(2)

Biological function  (11)

G protein-coupled receptor binding

(9)

GTPase activator activity

(9)

angiotensin receptor binding

(9)

arrestin family protein binding

(9)

enzyme inhibitor activity

(9)

histone acetyltransferase activity

(9)

insulin-like growth factor receptor binding

(9)

molecular adaptor activity

(9)

protein binding

(9)

transcription coactivator activity

(9)

ubiquitin protein ligase binding

(9)

Biological process  (20)

signal transduction

(11)

G protein-coupled receptor internalization

(9)

negative regulation of NF-kappaB transcription factor activity

(9)

negative regulation of Notch signaling pathway

(9)

negative regulation of interleukin-6 production

(9)

negative regulation of interleukin-8 production

(9)

negative regulation of protein ubiquitination

(9)

negative regulation of signal transduction

(9)

positive regulation of ERK1 and ERK2 cascade

(9)

positive regulation of Rho protein signal transduction

(9)

positive regulation of cardiac muscle hypertrophy

(9)

positive regulation of protein phosphorylation

(9)

positive regulation of receptor internalization

(9)

positive regulation of transcription by RNA polymerase II

(9)

proteasome-mediated ubiquitin-dependent protein catabolic process

(9)

protein transport

(9)

protein ubiquitination

(9)

regulation of transcription by RNA polymerase II

(9)

stress fiber assembly

(9)

ubiquitin-dependent protein catabolic process

(9)

Biological cell component  (16)

Golgi membrane

(9)

cell projection

(9)

chromatin

(9)

clathrin-coated pit

(9)

cytoplasm

(9)

cytoplasmic vesicle

(9)

cytoplasmic vesicle membrane

(9)

cytosol

(9)

endocytic vesicle membrane

(9)

lysosomal membrane

(9)

membrane

(9)

nuclear body

(9)

nucleoplasm

(9)

nucleus

(9)

plasma membrane

(9)

pseudopodium

(9)

Pfam accession / name  (2)

PF00339 : Arrestin_N

(13)

PF02752 : Arrestin_C

(13)

Diffraction protocol  (1)

Single wavelength

(4)

Diffraction radiation source type  (1)

Synchrotron

(4)

Diffraction source  (3)

SLS BEAMLINE X06SA

(2)

ESRF BEAMLINE ID14-1

(1)

SLS BEAMLINE X06DA

(1)

Synchrotron site  (2)

SLS

(3)

ESRF

(1)

Diffraction detector type  (2)

Pixel

(3)

CCD

(1)

Refinement software  (3)

PHENIX

(4)

BUSTER

(2)

REFMAC

(1)

EM microscope model  (2)

FEI TITAN KRIOS

(8)

TFS KRIOS

(2)

EM detector name  (5)

GATAN K3 BIOQUANTUM (6k x 4k)

(5)

FEI FALCON IV (4k x 4k)

(2)

GATAN K2 BASE (4k x 4k)

(1)

GATAN K2 QUANTUM (4k x 4k)

(1)

GATAN K2 SUMMIT (4k x 4k)

(1)

Representative Structures

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