Filter by :
Entry Information
Entry status
(1)
Experimental methods
(2)
Electron Microscopy
(1)
Solution NMR
(1)
Authors
(23)
Acton TB
(1)
Ding B
(1)
Everett JK
(1)
Glynn SE
(1)
Janua H
(1)
Kennedy MA
(1)
Kohan E
(1)
Lander GC
(1)
Lee H
(1)
Lee HW
(1)
Lorigan GA
(1)
Mitochondrial Protein Partnership (MPP)
(1)
Montelione GT
(1)
Northeast Structural Genomics Consortium (NESG)
(1)
Prestegard JH
(1)
Puchades C
(1)
Ramelot TA
(1)
Sahu ID
(1)
Shastry R
(1)
Song A
(1)
Wiseman RL
(1)
Xiao R
(1)
Yang Y
(1)
Homo / hetero assembly
(2)
hetero
(1)
homo
(1)
Assembly composition
(2)
protein structure
(1)
protein/protein complex
(1)
Assembly polymer count
(2)
decamer
(1)
monomer
(1)
Resolution distribution
2.5 - 3
(1)
Release year distribution
2010 - 2015
(1)
2015 - 2020
(1)
Journal
(2)
FEBS Lett
(1)
Mol Cell
(1)
Macromolecules
Organism superkingdom
(1)
Eukaryota
(2)
Organism name
(1)
Homo sapiens
(2)
Molecule name
(3)
AFG3-like protein 2
(2)
Mitochondrial inner membrane m-AAA protease component AFG3L2
(2)
Paraplegin-like protein
(2)
Molecule type
(1)
Protein
(2)
Gene names
(1)
AFG3L2
(2)
Interacting Molecules
(1)
Substrate
(1)
Interacting ligands
(4)
ADP : ADENOSINE-5'-DIPHOSPHATE
(1)
ANP : PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
(1)
MG : MAGNESIUM ION
(1)
ZN : ZINC ION
(1)
Function and Biology
Biological function
(5)
ATP binding
(2)
ATP-dependent peptidase activity
(2)
metalloendopeptidase activity
(2)
ATP hydrolysis activity
(1)
zinc ion binding
(1)
Biological process
(1)
proteolysis
(1)
Biological cell component
(1)
membrane
(2)
Sequence and Structure classification
CATH class
(1)
Alpha Beta
(1)
CATH topology
(1)
name from scop
(1)
Pfam accession / name
(4)
PF00004 : AAA
(1)
PF01434 : Peptidase_M41
(1)
PF06480 : FtsH_ext
(1)
PF17862 : AAA_lid_3
(1)
Experimental Information
Refinement software
(1)
PHENIX
(1)
EM microscope model
(1)
FEI TECNAI ARCTICA
(1)
EM detector name
(1)
GATAN K2 SUMMIT (4k x 4k)
(1)
NMR
NMR software packages
(12)
AutoStructure
(1)
CNS
(1)
CYANA
(1)
NMRPipe
(1)
PALES
(1)
PINE
(1)
PSVS
(1)
Sparky
(1)
TALOS+
(1)
TopSpin
(1)
VnmrJ
(1)
Xplor-NIH
(1)
NMR Field Strength
500.0 - 600
(1)
600.0 - 700
(1)
800.0 - 900
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 2 of 2
Select all entries on this page
human m-AAA protease AFG3L2, substrate-bound
Lander GC, Puchades C
Mol Cell
(2019)
[PMID: 31327635 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
m-AAA protease complex, AFG3L2 variant and peptide
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-167170 (Preferred)
search this ID
PDBe-KB:
Q9Y4W6
Solution NMR Structure of the mitochondrial inner membrane domain (residues 164-251), FtsH_ext, from the paraplegin-like protein AFG3L2 from Homo sapiens, Northeast Structural Genomics Consortium Target HR6741A
Ramelot TA, Yang Y, Lee H, Janua H, Kohan E, Shastry R, Acton TB, Xiao R, Everett JK, Prestegard JH, Montelione GT, Kennedy MA, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
FEBS Lett
(2013)
[PMID: 24055473 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Mitochondrial inner membrane m-AAA protease component AFG3L2
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-195252 (Preferred)
search this ID
PDBe-KB:
Q9Y4W6
Entries 1 to 2 of 2