Uniprot accession / id : Q8R527  OR   Uniprot accession / id : P17081  OR   Uniprot accession / id : E5RFZ3
 
Filter by :
Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (5)
Ahmadian MR
(1)
Carlier MF
(1)
Dvorsky R
(1)
Fiegen D
(1)
Hemsath L
(1)
 
Homo / hetero assembly  (1)
homo
(1)
 
Assembly composition  (1)
protein structure
(1)
 
Assembly polymer count  (1)
monomer
(1)
 
Resolution distribution
2.5 - 3
(1)
 
Release year distribution
2000 - 2005
(1)
2005 - 2010
(1)
 
Journal  (1)
Mol Cell
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (3)
Ras-like protein TC10
(1)
Ras-like protein family member 7A
(1)
Rho-related GTP-binding protein RhoQ
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (4)
ARHQ
(1)
RASL7A
(1)
RHOQ
(1)
TC10
(1)
 
Interacting ligands  (2)
GNP : PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
(1)
MG : MAGNESIUM ION
(1)
 
Function and Biology
EC number / name  (1)
3.6.5.2 : Small monomeric GTPase
(1)
 
Biological function  (7)
GBD domain binding
(1)
GTP binding
(1)
GTPase activity
(1)
nucleotide binding
(1)
profilin binding
(1)
protein binding
(1)
protein kinase binding
(1)
 
Biological process  (15)
GTP metabolic process
(1)
actin filament organization
(1)
cellular response to insulin stimulus
(1)
cortical actin cytoskeleton organization
(1)
endocytosis
(1)
establishment of cell polarity
(1)
insulin receptor signaling pathway
(1)
negative regulation of protein localization to plasma membrane
(1)
positive regulation of D-glucose import
(1)
positive regulation of filopodium assembly
(1)
positive regulation of transcription by RNA polymerase II
(1)
regulation of actin cytoskeleton organization
(1)
regulation of cell shape
(1)
signal transduction
(1)
small GTPase-mediated signal transduction
(1)
 
Biological cell component  (7)
Golgi-associated vesicle membrane
(1)
actin filament
(1)
cytoplasm
(1)
extracellular exosome
(1)
membrane
(1)
membrane raft
(1)
plasma membrane
(1)
 
Sequence and Structure classification
SCOP fold  (1)
P-loop containing nucleoside triphosphate hydrolases
(1)
 
SCOP family  (1)
G proteins
(1)
 
CATH class  (1)
Alpha Beta
(1)
 
CATH topology  (1)
Rossmann fold
(1)
 
Pfam accession / name  (1)
PF00071 : Ras
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(1)
 
Diffraction radiation source type  (1)
Synchrotron
(1)
 
Diffraction source  (1)
ESRF BEAMLINE ID14-1
(1)
 
Synchrotron site  (1)
ESRF
(1)
 
Diffraction detector type  (1)
CCD
(1)
 
Refinement software  (1)
REFMAC
(1)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
Entries 1 to 1 of 1
Entries 1 to 1 of 1
 Select all entries on this page
Crystal Structure of the TC10 GppNHp complex
Hemsath L, Dvorsky R, Fiegen D, Carlier MF, Ahmadian MR
Mol Cell (2005) [PMID: 16246732  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: GNP    MG    GNP    MG   
Assembly name: Rho-related GTP-binding protein RhoQ (Preferred)   search this complex
PDBe complex ID: PDB-CPX-147865 (Preferred)   search this ID
PDBe-KB: P17081   
X-ray diffraction
2.65Å resolution
Released: 13 Sep 2005
Model geometry
Fit model/data
2atx
2atx
2atx
Entries 1 to 1 of 1
Entries 1 to 1 of 1