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(1)
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(2)
Solution NMR
(1)
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(1)
Authors
(15)
Center for Eukaryotic Structural Genomics (CESG)
(1)
Chang A
(1)
Hayashi F
(1)
Hengel SR
(1)
Inoue K
(1)
Ke H
(1)
Lee AL
(1)
Muto Y
(1)
Phillips GN
(1)
Phillips Jr GN
(1)
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
(1)
Sapienza PJ
(1)
Wang H
(1)
Yokoyama S
(1)
Zhang J
(1)
Homo / hetero assembly
(2)
hetero
(1)
homo
(1)
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(2)
protein structure
(1)
protein/protein complex
(1)
Assembly polymer count
(2)
dodecamer
(1)
monomer
(1)
Resolution distribution
1.0 - 1.5
(1)
Release year distribution
2005 - 2010
(2)
2010 - 2015
(1)
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Macromolecules
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Eukaryota
(2)
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Homo sapiens
(2)
Molecule name
(12)
PDZ domain-containing guanine nucleotide exchange factor 2
(2)
PDZ-GEF2
(2)
RA-GEF-2
(2)
Rap guanine nucleotide exchange factor 6
(2)
FAP-1
(1)
Fas-associated protein-tyrosine phosphatase 1
(1)
PTP-BAS
(1)
PTP-E1
(1)
Protein-tyrosine phosphatase 1E
(1)
Protein-tyrosine phosphatase PTPL1
(1)
Tyrosine-protein phosphatase non-receptor type 13
(1)
hPTPE1
(1)
Molecule type
(1)
Protein
(2)
Gene names
(6)
PDZGEF2
(2)
RAPGEF6
(2)
PNP1
(1)
PTP1E
(1)
PTPL1
(1)
PTPN13
(1)
Interacting Molecules
(2)
Rap guanine nucleotide exchange factor 6
(1)
Tyrosine-protein phosphatase non-receptor type 13
(1)
Interacting ligands
(2)
SCN : THIOCYANATE ION
(1)
SO4 : SULFATE ION
(1)
Function and Biology
EC number / name
(1)
3.1.3.48 : Protein-tyrosine-phosphatase
(1)
Sequence and Structure classification
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(1)
Mainly Beta
(2)
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(1)
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(2)
PF00027 : cNMP_binding
(1)
PF00595 : PDZ
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NMR Field Strength
700.0 - 800
(1)
800.0 - 900
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Representative Structures
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Entries 1 to 2 of 2
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Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide
Zhang J, Chang A, Ke H, Phillips Jr GN, Lee AL, Center for Eukaryotic Structural Genomics (CESG)
Biochemistry
(2010)
[PMID: 20839809 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Rap guanine nucleotide exchange factor 6 and Tyrosine-protein phosphatase non-receptor type 13
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-171441 (Preferred)
search this ID
Solution structure of the cNMP_binding domain of human Rap guanine nucleotide exchange factor 6
Inoue K, Muto Y, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Rap guanine nucleotide exchange factor 6
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-186255 (Preferred)
search this ID
PDBe-KB:
Q8TEU7
Entries 1 to 2 of 2