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Entry status
(1)
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(1)
X-ray diffraction
(1)
Authors
(7)
Cho YH
(1)
Jeong DG
(1)
Kim JH
(1)
Kim SJ
(1)
Ryu SE
(1)
Son JH
(1)
Yoon TS
(1)
Homo / hetero assembly
(1)
homo
(1)
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(1)
protein structure
(1)
Assembly polymer count
(1)
monomer
(1)
Resolution distribution
1.5 - 2
(1)
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2005 - 2010
(1)
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(1)
Acta Crystallogr D Biol Crystallogr
(1)
Macromolecules
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(1)
Eukaryota
(1)
Organism name
(1)
Homo sapiens
(1)
Molecule name
(3)
Dual specificity protein phosphatase 18
(1)
LMW-DSP20
(1)
Low molecular weight dual specificity phosphatase 20
(1)
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Gene names
(2)
DUSP18
(1)
LMWDSP20
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Interacting ligands
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ACT : ACETATE ION
(1)
EPE : 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
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Function and Biology
EC number / name
(2)
3.1.3.16 : Protein-serine/threonine phosphatase
(1)
3.1.3.48 : Protein-tyrosine-phosphatase
(1)
Biological function
(8)
MAP kinase tyrosine/serine/threonine phosphatase activity
(1)
hydrolase activity
(1)
phosphatase activity
(1)
phosphoprotein phosphatase activity
(1)
protein binding
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protein serine/threonine phosphatase activity
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protein tyrosine phosphatase activity
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protein tyrosine/serine/threonine phosphatase activity
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(4)
dephosphorylation
(1)
peptidyl-threonine dephosphorylation
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peptidyl-tyrosine dephosphorylation
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protein dephosphorylation
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cytoplasm
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membrane
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nucleoplasm
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Sequence and Structure classification
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Alpha Beta
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Protein-Tyrosine Phosphatase; Chain A
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Pfam accession / name
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PF00782 : DSPc
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Representative Structures
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Crystal structure of human DUSP18
Kim SJ, Ryu SE, Jeong DG, Cho YH, Yoon TS, Kim JH
Acta Crystallogr D Biol Crystallogr
(2006)
[PMID: 16699184 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Dual specificity protein phosphatase 18
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-185511 (Preferred)
search this ID
PDBe-KB:
Q8NEJ0
Entries 1 to 1 of 1