Uniprot accession / id : Q8VEB6  OR   Uniprot accession / id : Q9H777
 
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Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (17)
Allerston CK
(1)
Arrowsmith CH
(1)
Berridge G
(1)
Bountra C
(1)
Burgess-Brown N
(1)
Chaikuad A
(1)
Chalk R
(1)
Edwards A
(1)
Elkins JM
(1)
Gileadi C
(1)
Gileadi O
(1)
Krojer T
(1)
Latwiel SVA
(1)
Savitsky P
(1)
Vollmar M
(1)
Weigelt J
(1)
von Delft F
(1)
 
Homo / hetero assembly  (1)
homo
(1)
 
Assembly composition  (1)
protein structure
(1)
 
Assembly polymer count  (1)
dimer
(1)
 
Resolution distribution
1.5 - 2
(1)
 
Release year distribution
2010 - 2015
(1)
 
Journal  (1)
To be published
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (7)
Deleted in Ma29
(1)
ElaC homolog protein 1
(1)
RNase Z 1
(1)
Ribonuclease Z 1
(1)
Zinc phosphodiesterase ELAC protein 1
(1)
tRNA 3 endonuclease 1
(1)
tRNase Z 1
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (2)
D29
(1)
ELAC1
(1)
 
Interacting ligands  (4)
EDO : 1,2-ETHANEDIOL
(1)
NA : SODIUM ION
(1)
PO4 : PHOSPHATE ION
(1)
ZN : ZINC ION
(1)
 
Function and Biology
EC number / name  (1)
3.1.26.11 : tRNase Z
(1)
 
Biological function  (7)
3'-tRNA processing endoribonuclease activity
(1)
RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism
(1)
endonuclease activity
(1)
hydrolase activity
(1)
metal ion binding
(1)
nuclease activity
(1)
tRNA-specific ribonuclease activity
(1)
 
Biological process  (3)
rescue of stalled ribosome
(1)
tRNA 3'-end processing
(1)
tRNA processing
(1)
 
Biological cell component  (4)
cytoplasm
(1)
cytosol
(1)
nucleoplasm
(1)
nucleus
(1)
 
Sequence and Structure classification
CATH class  (1)
Alpha Beta
(1)
 
CATH topology  (1)
Metallo-beta-lactamase; Chain A
(1)
 
Pfam accession / name  (1)
PF00753 : Lactamase_B
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(1)
 
Diffraction radiation source type  (1)
Synchrotron
(1)
 
Diffraction source  (1)
DIAMOND BEAMLINE I03
(1)
 
Synchrotron site  (1)
Diamond
(1)
 
Diffraction detector type  (1)
CCD
(1)
 
Refinement software  (1)
REFMAC
(1)
 
Representative Structures
Representative Structures
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Crystal structure of Human tRNase Z, short form (ELAC1).
Allerston CK, Krojer T, Berridge G, Burgess-Brown N, Chaikuad A, Chalk R, Elkins JM, Gileadi C, Latwiel SVA, Savitsky P, Vollmar M, Arrowsmith CH, Weigelt J, Edwards A, Bountra C, von Delft F, Gileadi O
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: ZN    NA    ZN    EDO    NA    PO4   
Assembly name: Zinc phosphodiesterase ELAC protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-190656 (Preferred)   search this ID
PDBe-KB: Q9H777   
X-ray diffraction
1.7Å resolution
Released: 10 Aug 2011
Model geometry
Fit model/data
3zwf
3zwf
3zwf
Entries 1 to 1 of 1
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