Entry status  (1)

REL

(28)

Experimental methods  (1)

X-ray diffraction

(28)

Authors  (132)

Leitans J

(20)

Tars K

(20)

Kazaks A

(15)

Matulis D

(13)

Dudutiene V

(8)

Dudutienė V

(8)

Grazulis S

(8)

Gražulis S

(8)

Supuran CT

(8)

Zubriene A

(8)

Zubrienė A

(8)

Matuliene J

(7)

Matulienė J

(7)

Smirnov A

(7)

Zalubovskis R

(7)

Dvinskis E

(6)

Ivanova J

(6)

Mahon BP

(6)

Manakova E

(6)

McKenna R

(6)

Baranauskiene L

(5)

Baranauskienė L

(5)

Becker HM

(5)

Capkauskaite E

(5)

Dubois LJ

(5)

Fisher SZ

(5)

Gondi G

(5)

Jezepcikas L

(5)

Jezepčikas L

(5)

Kazokaite J

(5)

Kazokaitė J

(5)

Knecht W

(5)

Koruza K

(5)

Lambin P

(5)

Leitāns J

(5)

Linkuviene V

(5)

Linkuvienė V

(5)

Niemans R

(5)

Tārs K

(5)

Yaromina A

(5)

Zaksauskas A

(5)

Zakšauskas A

(5)

Zeidler R

(5)

Čapkauskaitė E

(5)

Fisher Z

(4)

Lafumat B

(4)

Nyblom M

(4)

Paketuryte V

(4)

Paketurytė V

(4)

Akopjana I

(3)

Balode A

(3)

Bogans J

(3)

Kairys V

(2)

Manakova L

(2)

Mickeviciute A

(2)

Mickevičiūtė A

(2)

Smirnoviene J

(2)

Smirnovienė J

(2)

Agbandje-McKenna M

(1)

Alterio V

(1)

Baronas D

(1)

Bhatt A

(1)

Brynda J

(1)

Collard R

(1)

De Simone G

(1)

Di Fiore A

(1)

Domraceva I

(1)

Domračeva I

(1)

Driscoll JM

(1)

Fabry M

(1)

Frost SC

(1)

Fábry M

(1)

Gedgaudas M

(1)

Hilvo M

(1)

Hopkins JB

(1)

Horejsi M

(1)

Horejsí M

(1)

Ivanova JN

(1)

Jachno J

(1)

Jaudzems K

(1)

Juozapaitiene V

(1)

Juozapaitienė V

(1)

Kaupinis A

(1)

Kozisek M

(1)

Kozísek M

(1)

Kral V

(1)

Král V

(1)

Kurian JJ

(1)

Kvietkauskaite A

(1)

Kvietkauskaitė A

(1)

Leita Ns JN

(1)

Lomelino CL

(1)

Mader P

(1)

Mboge MY

(1)

Meyer-Almes FJ

(1)

Monti SM

(1)

Murray AB

(1)

Nocentini A

(1)

Okoh C

(1)

Paketuryte-Latve V

(1)

 

More...

Homo / hetero assembly  (2)

homo

(27)

hetero

(1)

Assembly composition  (2)

protein structure

(27)

protein/protein complex

(1)

Assembly polymer count  (4)

dimer

(18)

monomer

(8)

tetramer

(1)

trimer

(1)

Resolution distribution

1.0 - 1.5

(3)

1.5 - 2

(13)

2.0 - 2.5

(11)

2.5 - 3

(1)

Release year distribution

2005 - 2010

(2)

2010 - 2015

(3)

2015 - 2020

(20)

2020 - 2025

(13)

Journal  (11)

Oncotarget

(5)

Acta Crystallogr D Struct Biol

(4)

Eur J Med Chem

(4)

J Med Chem

(4)

ChemMedChem

(3)

Biophys J

(2)

Int J Mol Sci

(2)

Biochemistry

(1)

Elife

(1)

Proc Natl Acad Sci U S A

(1)

Proteins

(1)

Organism superkingdom  (1)

Eukaryota

(28)

Organism name  (1)

Homo sapiens

(28)

Molecule name  (10)

CA-IX

(28)

CAIX

(28)

Carbonate dehydratase IX

(28)

Carbonic anhydrase 9

(28)

Carbonic anhydrase IX

(28)

Membrane antigen MN

(28)

P54/58N

(28)

RCC-associated antigen G250

(28)

Renal cell carcinoma-associated antigen G250

(28)

pMW1

(28)

Molecule type  (1)

Protein

(28)

Gene names  (3)

CA9

(28)

G250

(28)

MN

(28)

Interacting Molecules  (2)

Immunoglobulin Heavy chain Fab fragment

(1)

Immunoglobulin Light chain Fab fragment

(1)

Interacting ligands  (31)

ZN : ZINC ION

(27)

GOL : GLYCEROL

(10)

ACT : ACETATE ION

(3)

TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL

(3)

BMA : beta-D-mannopyranose

(2)

CL : CHLORIDE ION

(2)

FMT : FORMIC ACID

(2)

J8N : 4-chloranyl-~{N}-(3-oxidanylpropyl)-2-phenylsulfanyl-5-sulfamoyl-benzamide

(2)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(2)

7VZ : methyl 2-chloranyl-4-cyclohexylsulfanyl-5-sulfamoyl-benzoate

(1)

82E : 5-[1-(4-methoxyphenyl)-1,2,3-triazol-4-yl]thiophene-2-sulfonamide

(1)

9FK : 5-(1-naphthalen-1-yl-1,2,3-triazol-4-yl)thiophene-2-sulfonamide

(1)

A1IDV : 3-[[(1~{R},4~{Z})-cyclododec-4-en-1-yl]amino]-4-ethylsulfonyl-2,5,6-tris(fluoranyl)benzenesulfonamide

(1)

ACY : ACETIC ACID

(1)

AZM : 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE

(1)

ER5 : 4-[2-[3-(cyclododecylamino)-2,5,6-tris(fluoranyl)-4-sulfamoyl-phenyl]sulfanylethyl]benzoic acid

(1)

ETK : 4-[2-[3-(cyclooctylamino)-2,5,6-tris(fluoranyl)-4-sulfamoyl-phenyl]sulfanylethyl]benzoic acid

(1)

IO6 : 1,1,3-tris(oxidanylidene)-2-pentyl-1,2-benzothiazole-6-sulfonamide

(1)

IQ2 : 2-but-2-ynyl-1,1,3-tris(oxidanylidene)-1,2-benzothiazole-6-sulfonamide

(1)

IQE : 1,1,3-tris(oxidanylidene)-2-(2-phenylethyl)-1,2-benzothiazole-6-sulfonamide

(1)

J8Q : ~{N}-butyl-4-chloranyl-2-(2-phenylethylsulfanyl)-5-sulfamoyl-benzamide

(1)

J92 : methyl 4-[(4-chloranyl-2-cyclohexylsulfanyl-5-sulfamoyl-phenyl)carbonylamino]butanoate

(1)

MAN : alpha-D-mannopyranose

(1)

MKQ : 3,5-diphenylbenzenesulfonamide

(1)

MUE : naphthalene-2-sulfonamide

(1)

PO4 : PHOSPHATE ION

(1)

SO4 : SULFATE ION

(1)

V14 : 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide

(1)

V8O : 5-(5-methyl-6-quinolin-5-yl-pyridin-3-yl)thiophene-2-sulfonamide

(1)

V90 : 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide

(1)

Y0R : 5-[1-(4-methylphenyl)-1,2,3-triazol-4-yl]thiophene-2-sulfonamide

(1)

EC number / name  (1)

4.2.1.1 : Carbonic anhydrase

(28)

Biological function  (2)

carbonate dehydratase activity

(26)

zinc ion binding

(26)

CATH class  (1)

Alpha Beta

(10)

CATH topology  (1)

Carbonic Anhydrase II

(10)

Pfam accession / name  (1)

PF00194 : Carb_anhydrase

(27)

Diffraction protocol  (1)

Single wavelength

(28)

Diffraction radiation source type  (2)

Synchrotron

(27)

Rotating anode

(1)

Diffraction source  (8)

BESSY BEAMLINE 14.1

(9)

MAX IV BEAMLINE BioMAX

(8)

MAX II BEAMLINE I911-3

(6)

CHESS BEAMLINE F1

(1)

DIAMOND BEAMLINE I03

(1)

ELETTRA BEAMLINE 5.2R

(1)

ENRAF-NONIUS FR591

(1)

ESRF BEAMLINE BM30A

(1)

Synchrotron site  (7)

BESSY

(9)

MAX IV

(8)

MAX II

(6)

CHESS

(1)

Diamond

(1)

ELETTRA

(1)

ESRF

(1)

Diffraction detector type  (3)

Pixel

(18)

CCD

(9)

Image plate

(1)

Refinement software  (3)

REFMAC

(21)

PHENIX

(6)

CNS

(1)

Representative Structures

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