Entry status  (1)

REL

(1)

Experimental methods  (1)

X-ray diffraction

(1)

Authors  (3)

Chao KL

(1)

Herzberg O

(1)

Muthukumar L

(1)

Homo / hetero assembly  (1)

homo

(1)

Assembly composition  (1)

protein structure

(1)

Assembly polymer count  (1)

monomer

(1)

Resolution distribution

1.5 - 2

(1)

Release year distribution

2005 - 2010

(1)

Journal  (1)

Biochemistry

(1)

Organism superkingdom  (1)

Eukaryota

(1)

Organism name  (1)

Homo sapiens

(1)

Molecule name  (5)

Hyal-1

(1)

Hyaluronidase-1

(1)

Hyaluronoglucosaminidase-1

(1)

LuCa-1

(1)

Lung carcinoma protein 1

(1)

Molecule type  (1)

Protein

(1)

Gene names  (2)

HYAL1

(1)

LUCA1

(1)

Interacting ligands  (5)

ACT : ACETATE ION

(1)

BMA : beta-D-mannopyranose

(1)

GOL : GLYCEROL

(1)

MAN : alpha-D-mannopyranose

(1)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(1)

EC number / name  (1)

3.2.1.35 : Hyaluronoglucosaminidase

(1)

Biological function  (5)

chondroitin hydrolase activity

(1)

hyalurononglucosaminidase activity

(1)

hydrolase activity

(1)

hydrolase activity, acting on glycosyl bonds

(1)

virus receptor activity

(1)

Biological process  (22)

carbohydrate metabolic process

(1)

cartilage development

(1)

cellular response to UV-B

(1)

cellular response to fibroblast growth factor stimulus

(1)

cellular response to interleukin-1

(1)

cellular response to pH

(1)

cellular response to platelet-derived growth factor stimulus

(1)

cellular response to tumor necrosis factor

(1)

chondroitin sulfate proteoglycan catabolic process

(1)

embryonic skeletal joint morphogenesis

(1)

glycosaminoglycan catabolic process

(1)

hyaluronan catabolic process

(1)

hyaluronan metabolic process

(1)

inflammatory response

(1)

negative regulation of cell growth

(1)

positive regulation of angiogenesis

(1)

positive regulation of cell adhesion

(1)

positive regulation of cell growth

(1)

positive regulation of hyaluranon cable assembly

(1)

response to antibiotic

(1)

response to reactive oxygen species

(1)

response to virus

(1)

Biological cell component  (7)

cytoplasmic vesicle

(1)

extracellular exosome

(1)

extracellular region

(1)

extracellular space

(1)

hyaluranon cable

(1)

lysosomal lumen

(1)

lysosome

(1)

CATH class  (1)

Alpha Beta

(1)

CATH topology  (1)

TIM Barrel

(1)

Pfam accession / name  (1)

PF01630 : Glyco_hydro_56

(1)

Diffraction protocol  (1)

Single wavelength

(1)

Diffraction radiation source type  (1)

Synchrotron

(1)

Diffraction source  (1)

APS BEAMLINE 22-BM

(1)

Synchrotron site  (1)

APS

(1)

Diffraction detector type  (1)

CCD

(1)

Refinement software  (1)

REFMAC

(1)

Representative Structures

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