Uniprot accession / id : Q921C3  OR   Uniprot accession / id : Q9NSI6  OR   Uniprot accession / id : H7C409
 
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Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (22)
Arrowsmith CH
(1)
Barsyte-Lovejoy D
(1)
Bountra C
(1)
Edwards A
(1)
Felletar I
(1)
Filippakopoulos P
(1)
Gileadi O
(1)
Gingras AC
(1)
Keates T
(1)
Knapp S
(1)
Krojer T
(1)
Lambert JP
(1)
Mangos M
(1)
Muller S
(1)
Muniz J
(1)
Müller S
(1)
Pawson T
(1)
Picaud S
(1)
Structural Genomics Consortium (SGC)
(1)
Volkmer R
(1)
Von Delft F
(1)
Weigelt J
(1)
 
Homo / hetero assembly  (1)
homo
(1)
 
Assembly composition  (1)
protein structure
(1)
 
Assembly polymer count  (1)
monomer
(1)
 
Resolution distribution
1.5 - 2
(1)
 
Release year distribution
2010 - 2015
(1)
 
Journal  (1)
Cell
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (2)
Bromodomain and WD repeat-containing protein 1
(1)
WD repeat-containing protein 9
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (3)
BRWD1
(1)
C21orf107
(1)
WDR9
(1)
 
Interacting ligands  (1)
ACT : ACETATE ION
(1)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(1)
 
CATH topology  (1)
Histone Acetyltransferase; Chain A
(1)
 
Pfam accession / name  (1)
PF00439 : Bromodomain
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(1)
 
Diffraction radiation source type  (1)
Synchrotron
(1)
 
Diffraction source  (1)
DIAMOND BEAMLINE I02
(1)
 
Synchrotron site  (1)
Diamond
(1)
 
Diffraction detector type  (1)
CCD
(1)
 
Refinement software  (1)
REFMAC
(1)
 
Representative Structures
Representative Structures
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Crystal structure of the second bromodomain of human bromodomain and WD repeat-containing protein 1 isoform A (WDR9)
Filippakopoulos P, Felletar I, Picaud S, Keates T, Krojer T, Muniz J, Gileadi O, Von Delft F, Arrowsmith CH, Edwards A, Weigelt J, Bountra C, Knapp S, Structural Genomics Consortium (SGC)
Cell (2012) [PMID: 22464331  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: ACT    ACT   
Assembly name: Bromodomain and WD repeat-containing protein 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-192592 (Preferred)   search this ID
PDBe-KB: Q9NSI6   
X-ray diffraction
1.74Å resolution
Released: 16 Feb 2011
Model geometry
Fit model/data
3q2e
3q2e
3q2e
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