Entry status  (1)

REL

(20)

Experimental methods  (2)

Electron Microscopy

(15)

X-ray diffraction

(5)

Authors  (97)

Hurley JH

(7)

Sabatini DM

(7)

Rogala KB

(6)

Shen K

(5)

Yu Z

(5)

Anandapadamanaban M

(4)

Berndt A

(4)

Chou HT

(4)

Fromm SA

(4)

Huber LA

(4)

Johnson CM

(4)

Kaufman J

(4)

Masson GR

(4)

Perisic O

(4)

Santhanam B

(4)

Williams RL

(4)

de Araujo MEG

(4)

Ballabio A

(3)

Cui Z

(3)

Egri SB

(3)

Esposito A

(3)

Hurley J

(3)

Lawrence RE

(3)

Monfregola J

(3)

Napolitano G

(3)

Ouch C

(3)

Song K

(3)

Xu C

(3)

Brignole EJ

(2)

Huang RK

(2)

Yokom AL

(2)

Zoncu R

(2)

Abu-Remaileh M

(1)

Arrowsmith CH

(1)

Bianchi LF

(1)

Bochkarev A

(1)

Bomaliyamu A

(1)

Bottino AMS

(1)

Bountra C

(1)

Chantranupong L

(1)

Choe A

(1)

Condon KJ

(1)

Crombet L

(1)

Dueholm R

(1)

Dunzendorfer-Matt T

(1)

Edwards AM

(1)

Fils AP

(1)

Fu Y

(1)

Furnrohr BG

(1)

Fürnrohr BG

(1)

Gu X

(1)

Guan X

(1)

Hong C

(1)

Jansen RM

(1)

Kedir JF

(1)

Kim DJ

(1)

Kitamura A

(1)

Kremser L

(1)

Laqtom NN

(1)

Leary D

(1)

Lechner S

(1)

Li S

(1)

Lim CY

(1)

Lindner HH

(1)

Nada S

(1)

Nakagawa A

(1)

Nakai M

(1)

Nakai T

(1)

Nakatsumi H

(1)

Nakayama KI

(1)

Naschberger A

(1)

Nedyalkova L

(1)

Niehaus A

(1)

Offterdinger M

(1)

Ogawa A

(1)

Okada M

(1)

Overwijn D

(1)

Park H

(1)

Peruzzo R

(1)

Samelson AJ

(1)

Scheffzek K

(1)

Shivalingaiah G

(1)

Standley DM

(1)

Stasyk T

(1)

Structural Genomics Consortium (SGC)

(1)

Tempel W

(1)

Thelen AM

(1)

Tong Y

(1)

Valenstein ML

(1)

Weigelt J

(1)

Welti S

(1)

Yamashita E

(1)

Yonehara R

(1)

Young LN

(1)

Yu ZH

(1)

Zhong N

(1)

Zhou SX

(1)

Homo / hetero assembly  (2)

hetero

(19)

homo

(1)

Assembly composition  (2)

protein/protein complex

(19)

protein structure

(1)

Assembly polymer count  (12)

decamer

(4)

octamer

(3)

dimer

(2)

heptamer

(2)

nonamer

(2)

36-mer

(1)

dodecamer

(1)

heptadecamer

(1)

hexadecamer

(1)

octadecamer

(1)

pentamer

(1)

tetramer

(1)

Resolution distribution

1.0 - 1.5

(1)

2.0 - 2.5

(2)

2.5 - 3

(3)

3.0 - 3.5

(5)

3.5 - 4

(7)

5.0 - 5.5

(1)

6.0 - 6.5

(1)

Release year distribution

2005 - 2010

(1)

2010 - 2015

(1)

2015 - 2020

(12)

2020 - 2025

(9)

Journal  (8)

Science

(7)

Nature

(4)

Mol Cell

(3)

Nat Struct Mol Biol

(2)

Cell

(1)

Nat Commun

(1)

Sci Adv

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(20)

Organism name  (2)

Homo sapiens

(19)

Mus musculus

(1)

Molecule name  (5)

GTPase-interacting protein 2

(20)

Rag C

(20)

RagC

(20)

Ras-related GTP-binding protein C

(20)

TIB929

(20)

Molecule type  (1)

Protein

(20)

Gene names  (2)

RRAGC

(19)

Rragc

(1)

Interacting Molecules  (19)

Ras-related GTP-binding protein A

(19)

Ragulator complex protein LAMTOR1

(14)

Ragulator complex protein LAMTOR2

(14)

Ragulator complex protein LAMTOR3

(14)

Ragulator complex protein LAMTOR4

(14)

Ragulator complex protein LAMTOR5

(14)

Regulatory-associated protein of mTOR

(6)

GATOR1 complex protein DEPDC5

(4)

GATOR1 complex protein NPRL2

(4)

GATOR1 complex protein NPRL3

(4)

Serine/threonine-protein kinase mTOR

(4)

Target of rapamycin complex subunit LST8

(4)

Folliculin

(3)

Folliculin-interacting protein 2

(3)

Neutral amino acid transporter 9

(3)

Transcription factor EB

(3)

Glutathione S-transferase class-mu 26 kDa isozyme

(1)

Proline-rich AKT1 substrate 1

(1)

Ras-related GTP-binding protein C

(1)

Interacting ligands  (9)

GDP : GUANOSINE-5'-DIPHOSPHATE

(10)

MG : MAGNESIUM ION

(3)

AF3 : ALUMINUM FLUORIDE

(2)

GNP : PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER

(2)

L8S : 9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione

(2)

ACT : ACETATE ION

(1)

BEF : BERYLLIUM TRIFLUORIDE ION

(1)

CZC : [(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate

(1)

U3J : xanthosine diphosphate

(1)

Biological function  (12)

GTP binding

(20)

GDP binding

(17)

GTPase activity

(17)

GTPase binding

(17)

enzyme-substrate adaptor activity

(17)

hydrolase activity

(17)

magnesium ion binding

(17)

molecular adaptor activity

(17)

nucleotide binding

(17)

protein binding

(17)

protein heterodimerization activity

(17)

protein-membrane adaptor activity

(17)

Biological process  (16)

DNA-templated transcription

(17)

RNA splicing

(17)

apoptotic process

(17)

cellular response to amino acid starvation

(17)

cellular response to amino acid stimulus

(17)

cellular response to nutrient levels

(17)

cellular response to starvation

(17)

negative regulation of autophagy

(17)

positive regulation of TORC1 signaling

(17)

protein localization

(17)

protein localization to lysosome

(17)

protein localization to membrane

(17)

regulation of TOR signaling

(17)

regulation of TORC1 signaling

(17)

response to amino acid

(17)

small GTPase-mediated signal transduction

(17)

Biological cell component  (10)

FNIP-folliculin RagC/D GAP

(17)

Gtr1-Gtr2 GTPase complex

(17)

cytoplasm

(17)

cytosol

(17)

intracellular membrane-bounded organelle

(17)

lysosomal membrane

(17)

lysosome

(17)

membrane

(17)

nucleoplasm

(17)

nucleus

(17)

CATH class  (1)

Alpha Beta

(3)

CATH topology  (2)

Beta-Lactamase

(2)

Rossmann fold

(1)

Pfam accession / name  (1)

PF04670 : Gtr1_RagA

(18)

Diffraction protocol  (1)

Single wavelength

(5)

Diffraction radiation source type  (1)

Synchrotron

(5)

Diffraction source  (5)

APS BEAMLINE 19-ID

(1)

ESRF BEAMLINE ID23-1

(1)

ESRF BEAMLINE ID30B

(1)

ESRF BEAMLINE MASSIF-3

(1)

SPRING-8 BEAMLINE BL44XU

(1)

Synchrotron site  (3)

ESRF

(3)

APS

(1)

SPring-8

(1)

Diffraction detector type  (2)

Pixel

(3)

CCD

(2)

Refinement software  (4)

PHENIX

(12)

REFMAC

(4)

phenix.real_space_refine

(3)

BUSTER

(1)

EM microscope model  (2)

FEI TITAN KRIOS

(14)

FEI TALOS ARCTICA

(1)

EM detector name  (5)

GATAN K2 SUMMIT (4k x 4k)

(5)

GATAN K3 BIOQUANTUM (6k x 4k)

(5)

GATAN K3 (6k x 4k)

(3)

GATAN K2 BASE (4k x 4k)

(1)

GATAN K2 QUANTUM (4k x 4k)

(1)

Representative Structures

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