Uniprot accession / id : Q9CWW6  OR   Uniprot accession / id : Q9Y237  OR   Uniprot accession / id : H0Y610
 
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Entry Information
Entry status  (1)
REL
(5)
 
Experimental methods  (2)
X-ray diffraction
(3)
Solution NMR
(2)
 
Authors  (27)
Bayer P
(4)
Blankenfeldt W
(3)
Hoppstock L
(3)
Link NM
(3)
Matena A
(3)
Mueller JW
(3)
Rueppel A
(3)
Ruppel A
(2)
Rüppel A
(2)
Fanghanel J
(1)
Fanghänel J
(1)
Fischer G
(1)
Fujimori F
(1)
Fukumori Y
(1)
Ito Y
(1)
Kigawa T
(1)
Muller J
(1)
Müller J
(1)
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
(1)
Rahfeld JU
(1)
Rahfeld UJ
(1)
Rascher C
(1)
Sekerina E
(1)
Shirouzu M
(1)
Terada T
(1)
Uchida T
(1)
Yokoyama S
(1)
 
Homo / hetero assembly  (1)
homo
(5)
 
Assembly composition  (1)
protein structure
(5)
 
Assembly polymer count  (1)
monomer
(5)
 
Resolution distribution
0.5 - 1
(2)
1.0 - 1.5
(1)
 
Release year distribution
2000 - 2005
(2)
2010 - 2015
(3)
 
Journal  (3)
J Am Chem Soc
(2)
J Mol Biol
(2)
To be published
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(5)
 
Organism name  (1)
Homo sapiens
(5)
 
Molecule name  (12)
PPIase Pin4
(5)
Par14
(5)
Par17
(5)
Parvulin-14
(5)
Parvulin-17
(5)
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4
(5)
Peptidyl-prolyl cis-trans isomerase Pin4
(5)
Peptidyl-prolyl cis/trans isomerase EPVH
(5)
Rotamase Pin4
(5)
hEPVH
(5)
hPar14
(5)
hPar17
(5)
 
Molecule type  (1)
Protein
(5)
 
Gene names  (1)
PIN4
(5)
 
Interacting ligands  (4)
SO4 : SULFATE ION
(3)
D1D : (4S,5S)-1,2-DITHIANE-4,5-DIOL
(2)
NA : SODIUM ION
(2)
CL : CHLORIDE ION
(1)
 
Function and Biology
EC number / name  (1)
5.2.1.8 : Peptidylprolyl isomerase
(5)
 
Biological function  (2)
DNA binding
(5)
peptidyl-prolyl cis-trans isomerase activity
(5)
 
Biological process  (1)
rRNA processing
(5)
 
Sequence and Structure classification
SCOP fold  (1)
FKBP-like
(2)
 
SCOP family  (1)
FKBP immunophilin/proline isomerase
(2)
 
CATH class  (1)
Alpha Beta
(5)
 
CATH topology  (1)
Chitinase A; domain 3
(5)
 
Pfam accession / name  (1)
PF13616 : Rotamase_3
(5)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(3)
 
Diffraction radiation source type  (2)
Synchrotron
(2)
Rotating anode
(1)
 
Diffraction source  (2)
SLS BEAMLINE X10SA
(2)
RIGAKU MICROMAX-007 HF
(1)
 
Synchrotron site  (1)
SLS
(2)
 
Diffraction detector type  (2)
CCD
(2)
Image plate
(1)
 
Refinement software  (2)
REFMAC
(2)
PHENIX
(1)
 
NMR
NMR software packages  (7)
X-PLOR
(2)
ANSIG
(1)
AURELIA
(1)
Azara
(1)
Insight II
(1)
NDEE
(1)
XwinNMR
(1)
 
NMR Field Strength
400.0 - 500
(1)
500.0 - 600
(2)
600.0 - 700
(1)
 
Representative Structures
Representative Structures
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Entries 1 to 5 of 5
Entries 1 to 5 of 5
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0.8 A resolution crystal structure of human Parvulin 14
Mueller JW, Link NM, Matena A, Hoppstock L, Rueppel A, Bayer P, Blankenfeldt W
J Am Chem Soc (2011) [PMID: 22081960  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: SO4    CL   
Assembly name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-195093 (Preferred)   search this ID
PDBe-KB: Q9Y237   
X-ray diffraction
0.8Å resolution
Released: 7 Dec 2011
Model geometry
Fit model/data
3ui4
3ui4
3ui4
HUMAN PARVULIN-LIKE PEPTIDYL PROLYL CIS/TRANS ISOMERASE, HPAR14
Terada T, Shirouzu M, Fukumori Y, Fujimori F, Ito Y, Kigawa T, Yokoyama S, Uchida T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
J Mol Biol (2001) [PMID: 11162102  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-195093 (Preferred)   search this ID
PDBe-KB: Q9Y237   
Solution NMR
Released: 8 Aug 2001
Model geometry
Fit model/data
Data not analysed
1fjd
1fjd
1fjd
0.89 A resolution crystal structure of human Parvulin 14 in complex with oxidized DTT
Mueller JW, Link NM, Matena A, Hoppstock L, Rueppel A, Bayer P, Blankenfeldt W
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: D1D    NA    SO4    NA   
Assembly name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-195093 (Preferred)   search this ID
PDBe-KB: Q9Y237   
X-ray diffraction
0.89Å resolution
Released: 7 Nov 2012
Model geometry
Fit model/data
3ui6
3ui6
3ui6
Crystal structure of human Parvulin 14
Mueller JW, Link NM, Matena A, Hoppstock L, Rueppel A, Bayer P, Blankenfeldt W
J Am Chem Soc (2011) [PMID: 22081960  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: D1D    NA    SO4    NA   
Assembly name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-195093 (Preferred)   search this ID
PDBe-KB: Q9Y237   
X-ray diffraction
1.4Å resolution
Released: 7 Dec 2011
Model geometry
Fit model/data
3ui5
3ui5
3ui5
NMR STRUCTURE OF HUMAN PARVULIN HPAR14
Sekerina E, Rahfeld UJ, Muller J, Fischer G, Bayer P
J Mol Biol (2000) [PMID: 10966801  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-195093 (Preferred)   search this ID
PDBe-KB: Q9Y237   
Solution NMR
Released: 4 Apr 2001
Model geometry
Fit model/data
Data not analysed
1eq3
1eq3
1eq3
Entries 1 to 5 of 5
Entries 1 to 5 of 5