Entry status  (1)

REL

(7)

Experimental methods  (2)

Solution NMR

(4)

X-ray diffraction

(3)

Authors  (47)

Wrana JL

(5)

Forman-Kay JD

(3)

Ogunjimi AA

(3)

Sicheri F

(3)

Chong PA

(2)

Lin H

(2)

Wiesner S

(2)

Aragon E

(1)

Aragón E

(1)

Briant DJ

(1)

Chong A

(1)

Chowdhury A

(1)

Chung J

(1)

Di Guglielmo GM

(1)

Gao S

(1)

Goerner N

(1)

Gomes T

(1)

Holdermann I

(1)

Hyz K

(1)

Jackl M

(1)

Jaeckl M

(1)

Jäckl M

(1)

Kavsak P

(1)

Le Roy C

(1)

Lopes T

(1)

Macias MJ

(1)

Maspero E

(1)

Massague J

(1)

Massagué J

(1)

Pece-Barbara N

(1)

Polo S

(1)

Rasmussen RK

(1)

Rotin D

(1)

Sachdev SS

(1)

Seet BT

(1)

Sidhu SS

(1)

Singer AU

(1)

Stollmaier C

(1)

Strohaker T

(1)

Strohäker T

(1)

Teyra J

(1)

Wang H

(1)

Wang H-R

(1)

Wang HR

(1)

Wrana J

(1)

Xi Q

(1)

Zhang W

(1)

Homo / hetero assembly  (2)

hetero

(5)

homo

(2)

Assembly composition  (2)

protein/protein complex

(5)

protein structure

(2)

Assembly polymer count  (2)

dimer

(5)

monomer

(2)

Resolution distribution

2.0 - 2.5

(3)

Release year distribution

2000 - 2005

(1)

2005 - 2010

(4)

2010 - 2015

(2)

2015 - 2020

(1)

2020 - 2025

(1)

Journal  (7)

Cell

(1)

J Biol Chem

(1)

J Mol Biol

(1)

Mol Cell

(1)

Proc Natl Acad Sci U S A

(1)

Structure

(1)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(7)

Organism name  (1)

Homo sapiens

(7)

Molecule name  (23)

E3 ubiquitin-protein ligase SMURF2

(7)

HECT-type E3 ubiquitin transferase SMURF2

(7)

SMAD ubiquitination regulatory factor 2

(7)

SMAD-specific E3 ubiquitin-protein ligase 2

(7)

hSMURF2

(7)

MAD homolog 7

(3)

MAD homolog 8

(3)

Mothers against DPP homolog 7

(3)

Mothers against DPP homolog 8

(3)

Mothers against decapentaplegic homolog 7

(3)

Mothers against decapentaplegic homolog 8

(3)

SMAD 7

(3)

SMAD family member 7

(3)

Smad7

(3)

hSMAD7

(3)

Ubiquitin

(2)

60S ribosomal protein L40

(1)

CEP52

(1)

Large ribosomal subunit protein eL40

(1)

Polyubiquitin-B

(1)

Ubiquitin A-52 residue ribosomal protein fusion product 1

(1)

Ubiquitin-ribosomal protein eL40 fusion protein

(1)

rpL40

(1)

Molecule type  (1)

Protein

(7)

Gene names  (7)

SMURF2

(7)

MADH7

(3)

MADH8

(3)

SMAD7

(3)

UBA52

(1)

UBB

(1)

UBCEP2

(1)

Interacting Molecules  (3)

E3 ubiquitin-protein ligase SMURF2

(5)

Mothers against decapentaplegic homolog 7

(3)

Ubiquitin

(2)

Interacting ligands  (7)

NA : SODIUM ION

(2)

CL : CHLORIDE ION

(1)

DTT : 2,3-DIHYDROXY-1,4-DITHIOBUTANE

(1)

EDO : 1,2-ETHANEDIOL

(1)

GOL : GLYCEROL

(1)

PO4 : PHOSPHATE ION

(1)

SO4 : SULFATE ION

(1)

EC number / name  (1)

2.3.2.26 : HECT-type E3 ubiquitin transferase

(7)

Biological function  (1)

ubiquitin-protein transferase activity

(3)

CATH class  (2)

Mainly Beta

(3)

Alpha Beta

(1)

CATH topology  (5)

Ubiquitin Ligase Nedd4; Chain: W;

(2)

Hect, E3 ligase catalytic domain

(1)

Hect, E3 ligase catalytic domain fold

(1)

Hect, E3 ligase catalytic fold

(1)

Immunoglobulin-like

(1)

Pfam accession / name  (4)

PF00397 : WW

(3)

PF00632 : HECT

(3)

PF00240 : ubiquitin

(2)

PF00168 : C2

(1)

Diffraction protocol  (2)

Single wavelength

(2)

MAD

(1)

Diffraction radiation source type  (1)

Synchrotron

(3)

Diffraction source  (3)

APS BEAMLINE 14-BM-D

(1)

APS BEAMLINE 24-ID-E

(1)

SLS BEAMLINE X10SA

(1)

Synchrotron site  (2)

APS

(2)

SLS

(1)

Diffraction detector type  (1)

Pixel

(2)

Refinement software  (2)

PHENIX

(2)

REFMAC

(1)

NMR software packages  (7)

NMRPipe

(3)

ARIA

(2)

CNS

(2)

CARA

(1)

NMRView

(1)

TopSpin

(1)

XEASY

(1)

NMR Field Strength

400.0 - 500

(3)

500.0 - 600

(4)

600.0 - 700

(1)

700.0 - 800

(1)

800.0 - 900

(1)

Representative Structures

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