Uniprot accession / id : Q9JIL4  OR   Uniprot accession / id : Q5T2W1  OR   Uniprot accession / id : A0A0C4DG67
 
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Entry Information
Entry status  (1)
REL
(13)
 
Experimental methods  (2)
X-ray diffraction
(9)
Solution NMR
(4)
 
Authors  (62)
Birrane G
(5)
Kocher O
(5)
Krieger M
(4)
Pal R
(4)
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
(4)
Yokoyama S
(4)
Daniels K
(3)
Kigawa T
(3)
Yesilaltay A
(3)
Inoue M
(2)
Koshiba K
(2)
Niraula TN
(2)
Shechter S
(2)
Tomizawa T
(2)
Appleton BA
(1)
Arrowsmith C
(1)
Bountra C
(1)
Cooper C
(1)
Doyle D
(1)
Edwards A
(1)
Elkins J
(1)
Ernst A
(1)
Fenske S
(1)
Flayhan A
(1)
Gfeller D
(1)
Hajizadeh NR
(1)
Harada T
(1)
Hayashi F
(1)
Ivarsson Y
(1)
Johansson C
(1)
Kinsella BT
(1)
Koshiba S
(1)
Ladias JA
(1)
Loew C
(1)
Low C
(1)
Löw C
(1)
Mulvaney EP
(1)
Murray JW
(1)
Nagashima T
(1)
Oppermann U
(1)
Phan RH
(1)
Phillips C
(1)
Pieprzyk J
(1)
Pilka ES
(1)
Qin XR
(1)
Roos A
(1)
Salah E
(1)
Sankaran B
(1)
Sarma GN
(1)
Sato M
(1)
Shafqat N
(1)
Sidhu SS
(1)
Skopintsev P
(1)
Svergun DI
(1)
Taylor SS
(1)
Tsukamoto K
(1)
Watanabe S
(1)
Wiesmann C
(1)
Wikstrom M
(1)
Yue WW
(1)
Zhang Y
(1)
von Delft F
(1)
 
Homo / hetero assembly  (2)
homo
(11)
hetero
(2)
 
Assembly composition  (2)
protein structure
(11)
protein/protein complex
(2)
 
Assembly polymer count  (4)
monomer
(9)
dimer
(2)
icosamer
(1)
trimer
(1)
 
Resolution distribution
1.0 - 1.5
(2)
1.5 - 2
(4)
2.0 - 2.5
(2)
3.5 - 4
(1)
 
Release year distribution
2005 - 2010
(6)
2010 - 2015
(7)
2015 - 2020
(2)
 
Journal  (5)
To be published
(7)
J Biol Chem
(3)
J Mol Biol
(1)
PLoS One
(1)
Structure
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(13)
 
Organism name  (2)
Mus musculus
(7)
Homo sapiens
(6)
 
Molecule name  (13)
CFTR-associated protein of 70 kDa
(13)
NHERF-3
(13)
Na(+)/H(+) exchange regulatory cofactor NHE-RF3
(13)
Na(+)/H(+) exchanger regulatory factor 3
(13)
Na/Pi cotransporter C-terminal-associated protein 1
(13)
NaPi-Cap1
(13)
PDZ domain-containing protein 1
(13)
Sodium-hydrogen exchanger regulatory factor 3
(13)
PGI receptor
(1)
PGI2 receptor
(1)
Prostacyclin receptor
(1)
Prostaglandin I2 receptor
(1)
Prostanoid IP receptor
(1)
 
Molecule type  (1)
Protein
(13)
 
Gene names  (8)
Cap70
(7)
Nherf3
(7)
Pdzk1
(7)
CAP70
(6)
NHERF3
(6)
PDZD1
(6)
PDZK1
(6)
Ptgir
(1)
 
Interacting Molecules  (3)
A-kinase anchor protein 10, mitochondrial
(1)
Solute carrier family 15 member 2
(1)
cAMP-dependent protein kinase type II-alpha regulatory subunit
(1)
 
Interacting ligands  (9)
EDO : 1,2-ETHANEDIOL
(2)
GOL : GLYCEROL
(2)
ACT : ACETATE ION
(1)
CA : CALCIUM ION
(1)
CIT : CITRIC ACID
(1)
CL : CHLORIDE ION
(1)
PG0 : 2-(2-METHOXYETHOXY)ETHANOL
(1)
TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
(1)
ZN : ZINC ION
(1)
 
Sequence and Structure classification
CATH class  (1)
Mainly Beta
(13)
 
CATH topology  (1)
Pdz3 Domain
(13)
 
Pfam accession / name  (1)
PF00595 : PDZ
(13)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(9)
 
Diffraction radiation source type  (2)
Synchrotron
(8)
Rotating anode
(1)
 
Diffraction source  (6)
NSLS BEAMLINE X12C
(3)
NSLS BEAMLINE X29A
(2)
ALS BEAMLINE 5.0.1
(1)
ESRF BEAMLINE ID30B
(1)
RIGAKU MICROMAX-007
(1)
SLS BEAMLINE X10SA
(1)
 
Synchrotron site  (4)
NSLS
(5)
ALS
(1)
ESRF
(1)
SLS
(1)
 
Diffraction detector type  (3)
CCD
(7)
Image plate
(1)
Pixel
(1)
 
Refinement software  (2)
REFMAC
(6)
PHENIX
(3)
 
NMR
NMR software packages  (6)
CYANA
(4)
KUJIRA
(4)
NMRPipe
(4)
NMRView
(4)
XwinNMR
(3)
VNMR
(1)
 
NMR Field Strength
700.0 - 800
(4)
800.0 - 900
(4)
900.0 - 1000
(1)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
Entries 1 to 10 of 13
Entries 1 to 10 of 13
 Select all entries on this page
NHERF3 PDZ2 in Complex with a Phage-Derived Peptide
Appleton BA, Wiesmann C
J Mol Biol (2014) [PMID: 25158098  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: TRS    EDO    TRS   
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-178300 (Preferred)   search this ID
PDBe-KB: Q5T2W1   
X-ray diffraction
2.05Å resolution
Released: 10 Sep 2014
Model geometry
Fit model/data
4q2p
4q2p
4q2p
Molecular analysis of the interaction of the HDL-receptor SR-BI with the PDZ3 domain of its adaptor protein PDZK1
Kocher O, Birrane G, Krieger M
J Biol Chem (2011) [PMID: 21602281  ]
Source organism: Mus musculus  
Assembly composition: protein only structure
Bound ligands: CIT   
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-191607 (Preferred)   search this ID
PDBe-KB: Q9JIL4   
X-ray diffraction
1.499Å resolution
Released: 18 May 2011
Model geometry
Fit model/data
3r69
3r69
3r69
Solution structure of the third PDZ domain of PDZ domain containing protein 1
Qin XR, Nagashima T, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Mus musculus  
Assembly composition: protein only structure
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-191607 (Preferred)   search this ID
PDBe-KB: Q9JIL4   
Solution NMR
Released: 8 Dec 2006
Model geometry
Fit model/data
Data not analysed
2d90
2d90
2d90
Solution structures of the PDZ domain of mus musculus PDZ domain-containing protein 1
Sato M, Koshiba S, Watanabe S, Harada T, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Mus musculus  
Assembly composition: protein only structure
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-191607 (Preferred)   search this ID
PDBe-KB: Q9JIL4   
Solution NMR
Released: 29 Jan 2008
Model geometry
Fit model/data
Data not analysed
2edz
2edz
2edz
Solution Structure of Second PDZ domain of PDZ Domain Containing Protein 1
Niraula TN, Tomizawa T, Koshiba K, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-178299 (Preferred)   search this ID
PDBe-KB: Q5T2W1   
Solution NMR
Released: 26 Feb 2008
Model geometry
Fit model/data
Data not analysed
2eei
2eei
2eei
Solution Structure of Fourth PDZ domain of PDZ Domain Containing Protein 1
Niraula TN, Tomizawa T, Koshiba K, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-178299 (Preferred)   search this ID
PDBe-KB: Q5T2W1   
Solution NMR
Released: 26 Feb 2008
Model geometry
Fit model/data
Data not analysed
2eej
2eej
2eej
PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.
Loew C, Flayhan A, Pieprzyk J
Structure (2018) [PMID: 30220543  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: GOL   
Assembly name: Solute carrier family 15 member 2 and Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-172462 (Preferred)   search this ID
PDBe-KB: Q5T2W1    Q16348   
X-ray diffraction
1.503321Å resolution
Released: 26 Sep 2018
Model geometry
Fit model/data
6ezi
6ezi
6ezi
Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1
Sarma GN, Phan RH, Sankaran B, Taylor SS
To be published
Assembly composition: protein/protein complex
PDBe complex ID: PDB-CPX-129007 (Preferred)   search this ID
PDBe-KB: Q5T2W1    O43572    P12368   
X-ray diffraction
3.8Å resolution
Released: 5 Sep 2012
Model geometry
Fit model/data
3tmh
3tmh
3tmh
Molecular Analysis of the PDZ4 Domain of Mouse PDZK1
Birrane G, Kocher O, Krieger M
To be published
Source organism: Mus musculus  
Assembly composition: protein only structure
Bound ligands: GOL    PG0   
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-191607 (Preferred)   search this ID
PDBe-KB: Q9JIL4   
X-ray diffraction
1.7Å resolution
Released: 19 Aug 2015
Model geometry
Fit model/data
4r2z
4r2z
4r2z
Crystal structure of the fourth PDZ domain of PDZ domain-containing protein 1
Yue WW, Shafqat N, Pilka ES, Johansson C, Murray JW, Elkins J, Roos A, Cooper C, Phillips C, Salah E, von Delft F, Doyle D, Edwards A, Wikstrom M, Arrowsmith C, Bountra C, Oppermann U
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-178299 (Preferred)   search this ID
PDBe-KB: Q5T2W1   
X-ray diffraction
2.41Å resolution
Released: 3 Mar 2009
Model geometry
Fit model/data
2vsp
2vsp
2vsp
Entries 1 to 10 of 13
Entries 1 to 10 of 13