Entry status  (1)

REL

(13)

Experimental methods  (2)

X-ray diffraction

(11)

Electron Microscopy

(2)

Authors  (51)

Abreu RM

(6)

Fernandes PA

(6)

Macedo-Ribeiro S

(6)

Martins LM

(6)

Merski M

(6)

Moreira C

(6)

Pereira PJB

(6)

Ramos MJ

(6)

Barbosa Pereira PJ

(4)

Bose K

(2)

Alnemri ES

(1)

Appleton BA

(1)

Bhaumik P

(1)

Chai J

(1)

Ciarkowski A

(1)

Ciarkowski J

(1)

Clausen T

(1)

Deszcz L

(1)

Dubin G

(1)

Dutta S

(1)

Ehrmann JF

(1)

Fischer ES

(1)

Gieldon A

(1)

Gogova R

(1)

Golik P

(1)

Grabarczyk DB

(1)

Heinke M

(1)

Hudecz O

(1)

Hunkeler M

(1)

Jarzab M

(1)

Jin CY

(1)

Kurzbauer R

(1)

Li P

(1)

Li W

(1)

Lipinska B

(1)

Meinhart A

(1)

Mishra V

(1)

Parui AL

(1)

Shi Y

(1)

Shulkina A

(1)

Sidhu SS

(1)

Srinivasula SM

(1)

Versteeg GA

(1)

Wagh AR

(1)

Wenta T

(1)

Wiesmann C

(1)

Wu JW

(1)

Wu P

(1)

Zhang Y

(1)

Zhang Z

(1)

Zurawa-Janicka D

(1)

Homo / hetero assembly  (2)

homo

(10)

hetero

(3)

Assembly composition  (2)

protein structure

(10)

protein/protein complex

(3)

Assembly polymer count  (4)

trimer

(8)

monomer

(2)

pentamer

(2)

dimer

(1)

Resolution distribution

1.5 - 2

(8)

2.0 - 2.5

(1)

2.5 - 3

(1)

3.0 - 3.5

(1)

3.5 - 4

(1)

6.0 - 6.5

(1)

Release year distribution

2000 - 2005

(1)

2005 - 2010

(1)

2015 - 2020

(8)

2020 - 2025

(3)

Journal  (7)

Cell Death Dis

(6)

Science

(2)

Biosci Rep

(1)

Nat Struct Biol

(1)

PLoS One

(1)

Protein Sci

(1)

Structure

(1)

Organism superkingdom  (1)

Eukaryota

(13)

Organism name  (1)

Homo sapiens

(13)

Molecule name  (6)

High temperature requirement protein A2

(13)

HtrA2

(13)

Omi stress-regulated endoprotease

(13)

Serine protease 25

(13)

Serine protease HTRA2, mitochondrial

(13)

Serine proteinase OMI

(13)

Molecule type  (1)

Protein

(13)

Gene names  (3)

HTRA2

(13)

OMI

(13)

PRSS25

(13)

Interacting Molecules  (2)

Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

(2)

Serine protease HTRA2, mitochondrial

(1)

Interacting ligands  (5)

MES : 2-(N-MORPHOLINO)-ETHANESULFONIC ACID

(8)

CL : CHLORIDE ION

(3)

NA : SODIUM ION

(2)

EDO : 1,2-ETHANEDIOL

(1)

K : POTASSIUM ION

(1)

EC number / name  (1)

3.4.21.108 : HtrA2 peptidase

(13)

Biological function  (1)

serine-type endopeptidase activity

(12)

Biological process  (1)

proteolysis

(12)

SCOP fold  (2)

PDZ domain-like

(2)

Trypsin-like serine proteases

(1)

SCOP family  (2)

HtrA-like serine proteases

(2)

Prokaryotic proteases

(1)

CATH class  (1)

Mainly Beta

(10)

CATH topology  (2)

Pdz3 Domain

(10)

Thrombin, subunit H

(9)

Pfam accession / name  (2)

PF13365 : Trypsin_2

(12)

PF17820 : PDZ_6

(12)

Diffraction protocol  (2)

Single wavelength

(10)

MAD

(1)

Diffraction radiation source type  (2)

Synchrotron

(9)

Rotating anode

(2)

Diffraction source  (7)

ESRF BEAMLINE ID14-3

(3)

ESRF BEAMLINE ID14-1

(2)

RIGAKU MICROMAX-007 HF

(2)

ESRF BEAMLINE ID29

(1)

NSLS BEAMLINE X12C

(1)

RRCAT INDUS-2 BEAMLINE PX-BL21

(1)

SSRL BEAMLINE BL9-1

(1)

Synchrotron site  (4)

ESRF

(6)

NSLS

(1)

RRCAT INDUS-2

(1)

SSRL

(1)

Diffraction detector type  (3)

CCD

(6)

Image plate

(3)

Pixel

(1)

Refinement software  (4)

PHENIX

(9)

REFMAC

(3)

CNS

(1)

phenix.real_space_refine

(1)

EM microscope model  (1)

FEI TITAN KRIOS

(2)

EM detector name  (2)

FEI FALCON IV (4k x 4k)

(1)

GATAN K3 BIOQUANTUM (6k x 4k)

(1)

Representative Structures

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