Uniprot accession / id : Q9JJT9  OR   Uniprot accession / id : Q9H814
 
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Entry Information
Entry status  (1)
REL
(2)
 
Experimental methods  (2)
Electron Microscopy
(1)
Solution NMR
(1)
 
Authors  (14)
Cusack S
(2)
Dubiez E
(1)
Finderup Brask M
(1)
Foucher AE
(1)
Garland W
(1)
Heick Jensen T
(1)
Huard K
(1)
Kadlec J
(1)
Mackereth CD
(1)
Mourao A
(1)
Mourão A
(1)
Pellegrini E
(1)
Sattler M
(1)
Varrot A
(1)
 
Homo / hetero assembly  (1)
hetero
(2)
 
Assembly composition  (2)
RNA/protein complex
(1)
protein/protein complex
(1)
 
Assembly polymer count  (2)
dimer
(1)
tetramer
(1)
 
Resolution distribution
3.0 - 3.5
(1)
 
Release year distribution
2005 - 2010
(1)
2010 - 2015
(1)
2020 - 2025
(1)
 
Journal  (2)
Cell Rep
(1)
RNA
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(2)
 
Organism name  (1)
Homo sapiens
(2)
 
Molecule name  (2)
Phosphorylated adapter RNA export protein
(2)
RNA U small nuclear RNA export adapter protein
(2)
 
Molecule type  (1)
Protein
(2)
 
Gene names  (2)
PHAX
(2)
RNUXA
(2)
 
Interacting Molecules  (3)
5'-(AP*UP*CP*GP)-3'
(1)
Nuclear cap-binding protein subunit 1
(1)
Nuclear cap-binding protein subunit 2
(1)
 
Function and Biology
Biological function  (4)
RNA binding
(1)
mRNA cap binding complex binding
(1)
protein binding
(1)
toxic substance binding
(1)
 
Biological process  (3)
snRNA export from nucleus
(2)
RNA stabilization
(1)
protein transport
(1)
 
Biological cell component  (7)
Cajal body
(1)
cytoplasm
(1)
cytosol
(1)
neuronal cell body
(1)
nucleoplasm
(1)
nucleus
(1)
ribonucleoprotein complex
(1)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(1)
 
CATH topology  (1)
Arc Repressor Mutant, subunit A
(1)
 
Pfam accession / name  (1)
PF10258 : PHAX_RNA-bd
(2)
 
Representative Structures
Representative Structures
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Entries 1 to 2 of 2
Entries 1 to 2 of 2
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Structure of the human nuclear cap-binding complex bound to PHAX and m7G-capped RNA
Dubiez E, Pellegrini E, Foucher AE, Cusack S, Kadlec J
Cell Rep (2024) [PMID: 38175753  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: MGT    MGT   
Assembly name: Nuclear cap-binding complex and Phosphorylated adapter RNA export protein (Preferred)   search this complex
PDBe complex ID: PDB-CPX-273864 (Preferred)   search this ID
PDBe-KB: Q9H814    Q09161    P52298   
Electron Microscopy
3.46Å resolution
Released: 17 Jan 2024
Model geometry
Fit model/data
Data not analysed
8pnt
8pnt
8pnt
Solution Structure of PHAX-RBD in complex with ssRNA
Mourao A, Mackereth CD, Varrot A, Cusack S, Sattler M
RNA (2010) [PMID: 20430857  ]
Source organisms: Synthetic construct, Homo sapiens  
Assembly composition: RNA/protein complex
Assembly name: Phosphorylated adapter RNA export protein and RNA (Preferred)   search this complex
PDBe complex ID: PDB-CPX-190671 (Preferred)   search this ID
PDBe-KB: Q9H814   
Solution NMR
Released: 28 Apr 2010
Model geometry
Fit model/data
Data not analysed
2xc7
2xc7
2xc7
Entries 1 to 2 of 2
Entries 1 to 2 of 2