Uniprot accession / id : Q9JL25  OR   Uniprot accession / id : Q08116
 
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Entry Information
Entry status  (1)
REL
(2)
 
Experimental methods  (1)
X-ray diffraction
(2)
 
Authors  (25)
Arrowsmith C
(2)
Ball LJ
(2)
Dowler EF
(2)
Doyle DA
(2)
Edwards A
(2)
Fedorov OY
(2)
Gileadi C
(2)
Higman VA
(2)
Hutsell SQ
(2)
Kimple AJ
(2)
Schoch GA
(2)
Siderovski DP
(2)
Soundararajan M
(2)
Sundstrom M
(2)
Sundström M
(2)
Turnbull AP
(2)
Willard FS
(2)
Elkins JM
(1)
Gorrec F
(1)
Haroniti A
(1)
Structural Genomics Consortium (SGC)
(1)
Ugochukwu E
(1)
Weigelt J
(1)
Yang X
(1)
von Delft F
(1)
 
Homo / hetero assembly  (2)
hetero
(1)
homo
(1)
 
Assembly composition  (2)
protein structure
(1)
protein/protein complex
(1)
 
Assembly polymer count  (2)
dimer
(1)
monomer
(1)
 
Resolution distribution
1.5 - 2
(1)
2.5 - 3
(1)
 
Release year distribution
2000 - 2005
(1)
2005 - 2010
(2)
 
Journal  (1)
Proc Natl Acad Sci U S A
(2)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(2)
 
Organism name  (1)
Homo sapiens
(2)
 
Molecule name  (4)
B-cell activation protein BL34
(2)
Early response protein 1R20
(2)
RGS1
(2)
Regulator of G-protein signaling 1
(2)
 
Molecule type  (1)
Protein
(2)
 
Gene names  (4)
1R20
(2)
BL34
(2)
IER1
(2)
RGS1
(2)
 
Interacting Molecules  (1)
Guanine nucleotide-binding protein G(i) subunit alpha-1
(1)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(2)
 
CATH topology  (2)
Regulator of G-protein Signalling 4; domain 1
(2)
Regulator of G-protein Signalling 4; domain 2
(2)
 
Pfam accession / name  (1)
PF00615 : RGS
(2)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(2)
 
Diffraction radiation source type  (2)
Rotating anode
(1)
Synchrotron
(1)
 
Diffraction source  (2)
RIGAKU FR-E
(1)
SLS BEAMLINE X10SA
(1)
 
Synchrotron site  (1)
SLS
(1)
 
Diffraction detector type  (2)
CCD
(1)
Image plate
(1)
 
Refinement software  (1)
REFMAC
(2)
 
Representative Structures
Representative Structures
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30%
Entries 1 to 2 of 2
Entries 1 to 2 of 2
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Regulator of G-protein Signalling 1 (Human)
Elkins JM, Yang X, Soundararajan M, Schoch GA, Haroniti A, Sundstrom M, Edwards A, Arrowsmith C, Doyle DA
Proc Natl Acad Sci U S A (2008) [PMID: 18434541  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Regulator of G-protein signaling 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-170596 (Preferred)   search this ID
PDBe-KB: Q08116   
X-ray diffraction
2Å resolution
Released: 27 Jun 2005
Model geometry
Fit model/data
2bv1
2bv1
2bv1
Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1
Soundararajan M, Turnbull AP, Ugochukwu E, Gorrec F, von Delft F, Weigelt J, Edwards A, Arrowsmith C, Sundstrom M, Doyle DA, Structural Genomics Consortium (SGC)
Proc Natl Acad Sci U S A (2008) [PMID: 18434541  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: GDP    MG    ALF    GDP    MG    ALF   
Assembly name: Regulator of G-protein signaling 1 and Guanine nucleotide-binding protein G(i) subunit alpha-1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-158958 (Preferred)   search this ID
PDBe-KB: Q08116    P63096   
X-ray diffraction
2.55Å resolution
Released: 23 May 2006
Model geometry
Fit model/data
2gtp
2gtp
2gtp
Entries 1 to 2 of 2
Entries 1 to 2 of 2