Entry status  (1)

REL

(13)

Experimental methods  (1)

Electron Microscopy

(13)

Authors  (15)

Pavletich NP

(9)

Peralta C

(9)

Wang R

(9)

Wang S

(9)

Wang SL

(5)

Yaseen A

(5)

Arkinson C

(4)

Chaugule VK

(4)

Dhar A

(4)

Rennie ML

(4)

Walden H

(4)

Clarke M

(1)

Lemonidis K

(1)

Streetley J

(1)

Toth R

(1)

Homo / hetero assembly  (1)

hetero

(13)

Assembly composition  (2)

DNA/protein complex

(10)

protein/protein complex

(3)

Assembly polymer count  (7)

heptamer

(3)

nonadecamer

(3)

hexamer

(2)

pentamer

(2)

dimer

(1)

heptadecamer

(1)

hexadecamer

(1)

Resolution distribution

2.5 - 3

(2)

3.0 - 3.5

(2)

3.5 - 4

(3)

4.0 - 4.5

(6)

Release year distribution

2015 - 2020

(4)

2020 - 2025

(13)

Journal  (4)

Nat Struct Mol Biol

(6)

Nature

(4)

Sci Adv

(2)

EMBO J

(1)

Organism superkingdom  (1)

Eukaryota

(13)

Organism name  (1)

Homo sapiens

(13)

Molecule name  (23)

Fanconi anemia group D2 protein

(8)

Fanconi anemia group I protein

(8)

Protein FACD2

(8)

Protein FACI

(8)

Ubiquitin

(6)

Fanconi anemia, complementation group I

(5)

Polyubiquitin-C

(4)

Deubiquitinating enzyme 1

(3)

USP1-associated factor 1

(3)

Ubiquitin carboxyl-terminal hydrolase 1

(3)

Ubiquitin carboxyl-terminal hydrolase 1, N-terminal fragment

(3)

Ubiquitin thioesterase 1

(3)

Ubiquitin-specific-processing protease 1

(3)

WD repeat endosomal protein

(3)

WD repeat-containing protein 48

(3)

hUBP

(3)

p80

(3)

60S ribosomal protein L40

(2)

CEP52

(2)

Large ribosomal subunit protein eL40

(2)

Ubiquitin A-52 residue ribosomal protein fusion product 1

(2)

Ubiquitin-ribosomal protein eL40 fusion protein

(2)

rpL40

(2)

Molecule type  (1)

Protein

(13)

Gene names  (11)

FANCI

(13)

FACD

(8)

FANCD2

(8)

KIAA1794

(8)

UBC

(4)

KIAA1449

(3)

UAF1

(3)

USP1

(3)

WDR48

(3)

UBA52

(2)

UBCEP2

(2)

Interacting Molecules  (23)

Fanconi anemia group D2 protein

(13)

Fanconi anemia group I protein

(8)

Ubiquitin

(6)

E3 ubiquitin-protein ligase FANCL

(5)

Fanconi anemia core complex-associated protein 100

(5)

Fanconi anemia core complex-associated protein 20

(5)

Fanconi anemia group A protein

(5)

Fanconi anemia group B protein

(5)

Fanconi anemia group C protein

(5)

Fanconi anemia group E protein

(5)

Fanconi anemia group F protein

(5)

Fanconi anemia group G protein

(5)

DNA (61-MER)

(4)

Ubiquitin-conjugating enzyme E2 T

(4)

DNA (29-MER)

(3)

Ubiquitin carboxyl-terminal hydrolase 1

(3)

WD repeat-containing protein 48

(3)

DNA (22-MER)

(1)

DNA (25-MER)

(1)

DNA (26-MER)

(1)

DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')

(1)

DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')

(1)

DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')

(1)

Interacting ligands  (2)

ZN : ZINC ION

(3)

JDA : 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine

(1)

EC number / name  (1)

3.4.19.12 : Ubiquitinyl hydrolase 1

(3)

Biological function  (12)

DNA binding

(8)

DNA polymerase binding

(8)

protein binding

(8)

cysteine-type deubiquitinase activity

(3)

cysteine-type endopeptidase activity

(3)

cysteine-type peptidase activity

(3)

deubiquitinase activator activity

(3)

double-stranded DNA binding

(3)

hydrolase activity

(3)

peptidase activity

(3)

single-stranded DNA binding

(3)

ubiquitin binding

(3)

Biological process  (37)

DNA repair

(13)

DNA damage response

(8)

brain morphogenesis

(8)

cellular response to oxidative stress

(8)

double-strand break repair involved in meiotic recombination

(8)

gamete generation

(8)

homologous chromosome pairing at meiosis

(8)

interstrand cross-link repair

(8)

mitotic intra-S DNA damage checkpoint signaling

(8)

neuronal stem cell population maintenance

(8)

positive regulation of protein ubiquitination

(8)

regulation of CD40 signaling pathway

(8)

regulation of inflammatory response

(8)

regulation of regulatory T cell differentiation

(8)

response to gamma radiation

(8)

double-strand break repair via homologous recombination

(3)

embryonic organ development

(3)

homeostasis of number of cells

(3)

male gonad development

(3)

monoubiquitinated protein deubiquitination

(3)

multicellular organism growth

(3)

positive regulation of double-strand break repair via homologous recombination

(3)

positive regulation of epithelial cell proliferation

(3)

positive regulation of error-prone translesion synthesis

(3)

positive regulation of receptor signaling pathway via JAK-STAT

(3)

protein deubiquitination

(3)

proteolysis

(3)

regulation of DNA repair

(3)

regulation of protein monoubiquitination

(3)

regulation of protein stability

(3)

response to UV

(3)

seminiferous tubule development

(3)

single fertilization

(3)

skeletal system development

(3)

skeletal system morphogenesis

(3)

skin development

(3)

spermatogenesis

(3)

Biological cell component  (14)

DNA repair complex

(8)

chromatin

(8)

condensed chromosome

(8)

cytoplasm

(8)

cytosol

(8)

membrane

(8)

nuclear body

(8)

nucleolus

(8)

nucleoplasm

(8)

nucleus

(8)

endosome

(3)

intracellular membrane-bounded organelle

(3)

late endosome

(3)

lysosome

(3)

Pfam accession / name  (12)

PF14674 : FANCI_S1-cap

(13)

PF14675 : FANCI_S1

(13)

PF14676 : FANCI_S2

(13)

PF14677 : FANCI_S3

(13)

PF14678 : FANCI_S4

(13)

PF14679 : FANCI_HD1

(13)

PF14680 : FANCI_HD2

(13)

PF14631 : FancD2

(8)

PF00240 : ubiquitin

(6)

PF00400 : WD40

(3)

PF00443 : UCH

(3)

PF11816 : DUF3337

(3)

Refinement software  (2)

REFMAC

(9)

PHENIX

(3)

EM microscope model  (2)

FEI TITAN KRIOS

(11)

JEOL CRYO ARM 300

(2)

EM detector name  (3)

GATAN K2 SUMMIT (4k x 4k)

(6)

GATAN K3 (6k x 4k)

(5)

DIRECT ELECTRON DE-64 (8k x 8k)

(2)

Representative Structures

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