Entry status  (1)

REL

(92)

Experimental methods  (2)

X-ray diffraction

(89)

Solution NMR

(3)

Authors  (82)

Kunkel TA

(41)

Bebenek K

(39)

Pedersen LC

(38)

Garcia-Diaz M

(34)

Jamsen JA

(20)

Wilson SH

(20)

Shock DD

(19)

Krahn JM

(16)

Ho MC

(12)

Liu MS

(12)

Liu XX

(12)

Ramsden DA

(12)

Tsai HY

(12)

Tsai MD

(12)

Wu WJ

(12)

Burak MJ

(10)

Guja KE

(10)

Kaminski AM

(10)

Chiruvella KK

(8)

Derkunt B

(7)

Hambardjieva E

(7)

Moon AF

(5)

Gosavi RA

(4)

Kunkel T

(4)

Walker GC

(4)

Zhou P

(4)

Blanco L

(3)

Havener JM

(3)

Larrea AA

(3)

London RE

(3)

Perera L

(3)

Suo Z

(3)

Vyas R

(3)

Zahurancik WJ

(3)

Bian K

(2)

Chatterjee N

(2)

Chou KM

(2)

D'Souza S

(2)

DeRose EF

(2)

Fenton BA

(2)

Foley MC

(2)

Hemann MT

(2)

Hong J

(2)

Lee M

(2)

Li D

(2)

Mueller GA

(2)

Murray M

(2)

Murray MS

(2)

Najeeb J

(2)

Park H

(2)

Povirk LF

(2)

Ramos A

(2)

Schlick T

(2)

Wojtaszek J

(2)

Wojtaszek JL

(2)

Xue JY

(2)

Zhou RZ

(2)

Arora S

(1)

Borisonnik N

(1)

Calbert ML

(1)

Chandramouly G

(1)

D'Andrea AD

(1)

Davis BJ

(1)

Demidova EV

(1)

Gabel S

(1)

García-Díaz M

(1)

Jamsen J

(1)

Kent T

(1)

Kim H

(1)

Kirby TW

(1)

Lee C-J

(1)

Lee CJ

(1)

Liu J

(1)

London R

(1)

Minesinger B

(1)

Ozdemir AY

(1)

Picher AJ

(1)

Pomerantz RT

(1)

Tredinnick T

(1)

Tyagi M

(1)

Wang S

(1)

Xue Y

(1)

Homo / hetero assembly  (2)

hetero

(84)

homo

(7)

Assembly composition  (4)

DNA/protein complex

(79)

protein structure

(7)

DNA/DNA/RNA hybrid/protein complex

(3)

protein/protein complex

(2)

Assembly polymer count  (6)

tetramer

(67)

trimer

(8)

monomer

(6)

pentamer

(6)

dimer

(3)

hexamer

(1)

Resolution distribution

1.0 - 1.5

(1)

1.5 - 2

(41)

2.0 - 2.5

(32)

2.5 - 3

(13)

3.0 - 3.5

(2)

Release year distribution

2000 - 2005

(5)

2005 - 2010

(23)

2010 - 2015

(17)

2015 - 2020

(25)

2020 - 2025

(30)

Journal  (14)

Nat Commun

(25)

J Am Chem Soc

(12)

Nucleic Acids Res

(10)

Cell

(7)

EMBO J

(7)

DNA Repair (Amst)

(6)

Proc Natl Acad Sci U S A

(6)

To be published

(5)

J Biol Chem

(4)

Nat Struct Mol Biol

(4)

EMBO Rep

(2)

Not Published

(2)

Biochemistry

(1)

Mol Cell

(1)

Organism superkingdom  (1)

Eukaryota

(92)

Organism name  (2)

Homo sapiens

(88)

Mus musculus

(4)

Molecule name  (9)

DNA polymerase kappa

(92)

DNA polymerase beta-2

(88)

DNA polymerase lambda

(88)

Pol Lambda

(88)

Pol beta2

(88)

DINB protein

(4)

DINP

(4)

DNA repair protein REV1

(2)

Rev1-like terminal deoxycytidyl transferase

(2)

Molecule type  (1)

Protein

(92)

Gene names  (5)

POLL

(88)

Dinb1

(4)

Polk

(4)

Rev1

(2)

Rev1l

(2)

Interacting Molecules  (71)

DNA (5'-D(P*GP*CP*CP*G)-3')

(47)

DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3')

(25)

DNA (5'-D(*CP*AP*GP*TP*AP*C)-3')

(22)

5'-D(P*GP*CP*CP*G)-3'

(17)

DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3')

(11)

DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3')

(7)

DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3')

(7)

DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3')

(6)

5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3'

(5)

5'-D(*CP*AP*GP*TP*AP*CP*G)-3'

(4)

DNA (5'-D(*CP*AP*GP*TP*GP*C)-3')

(4)

DNA (5'-D(*CP*GP*GP*CP*AP*(8OG)P*TP*AP*CP*TP*G)-3')

(4)

Downstream Primer

(4)

Primer

(4)

Template

(4)

5'-D(*GP*CP*CP*G)-3'

(3)

DNA (5'-D(*CP*GP*GP*CP*(8OG)P*GP*TP*AP*CP*TP*G)-3')

(3)

DNA (5'-D(*TP*AP*CP*TP*G)-3')

(3)

5'-D(*CP*AP*GP*TP*AP*(2DT))-3'

(2)

5'-D(*CP*AP*GP*TP*AP*C)-3'

(2)

5'-D(*CP*AP*GP*TP*AP*G)-3'

(2)

5'-D(*CP*AP*GP*TP*AP*T)-3'

(2)

5'-D(*CP*GP*GP*CP*AP*AP*AP*TP*AP*CP*TP*G)-3'

(2)

5'-D(*CP*GP*GP*CP*AP*GP*CP*GP*CP*AP*C)-3'

(2)

5'-D(*CP*GP*GP*CP*CP*GP*AP*TP*AP*CP*TP*G)-3'

(2)

5'-D(*CP*GP*GP*CP*CP*TP*TP*AP*CP*TP*G)-3'

(2)

DNA (5'-D(*CP*AP*GP*TP*AP*(DOC))-3')

(2)

DNA (5'-D(*CP*AP*GP*TP*GP*CP*T)-3')

(2)

DNA (5'-D(*CP*GP*GP*CP*A)-3')

(2)

DNA (5'-D(*CP*GP*GP*CP*AP*G)-3')

(2)

DNA (5'-D(*CP*GP*GP*CP*AP*GP*C)-3')

(2)

DNA (5'-D(*GP*CP*AP*CP*TP*G)-3')

(2)

DNA (5'-D(P*DGP*DCP*DCP*DG)-3')

(2)

5'-D(*CP*AP*GP*TP*AP)-R(P*C)-3'

(1)

5'-D(*CP*AP*GP*TP*AP)-R(P*CP*A)-3'

(1)

5'-D(*CP*AP*GP*TP*AP*(O2C))-3'

(1)

5'-D(*CP*AP*GP*TP*AP*CP)-R(P*A)-3'

(1)

5'-D(*CP*AP*GP*TP*TP*CP*G)-3'

(1)

5'-D(*CP*GP*GP*CP*AP*AP*CP*GP*CP*AP*C)-3'

(1)

5'-D(*CP*GP*GP*CP*AP*AP*TP*AP*CP*TP*G)-3'

(1)

5'-D(*CP*GP*GP*CP*AP*GP*TP*TP*AP*CP*TP*G)-3'

(1)

5'-D(*CP*GP*GP*CP*CP*AP*AP*TP*AP*CP*TP*G)-3'

(1)

5'-D(*CP*GP*GP*CP*CP*GP*CP*TP*AP*CP*TP*G)-3'

(1)

5'-D(*CP*GP*GP*CP*CP*GP*TP*AP*CP*TP*G)-3'

(1)

5'-D(*CP*GP*GP*CP*CP*GP*TP*TP*AP*CP*TP*G)-3'

(1)

5'-D(*GP*TP*GP*CP*G)-3'

(1)

5'-D(*GP*TP*GP*CP*GP*C)-3'

(1)

5'-D(*GP*TP*GP*CP*GP*G)-3'

(1)

5'-D(P*CP*AP*GP*TP*A)-3'

(1)

5'-D(P*TP*AP*CP*TP*G)-3'

(1)

DNA

(1)

DNA (5'-D(*AP*CP*GP*CP*GP*GP*CP*A)-3')

(1)

DNA (5'-D(*AP*CP*TP*G)-3')

(1)

DNA (5'-D(*CP*AP*GP*TP*A)-3')

(1)

DNA (5'-D(*CP*AP*GP*TP*AP*A)-3')

(1)

DNA (5'-D(*CP*AP*GP*TP*AP*AP*T)-3')

(1)

DNA (5'-D(*CP*AP*GP*TP*AP*CP*(8OG))-3')

(1)

DNA (5'-D(*CP*AP*GP*TP*AP*CP*(CAR))-3')

(1)

DNA (5'-D(*CP*AP*GP*TP*AP*CP*(YQS))-3')

(1)

DNA (5'-D(*CP*AP*GP*TP*AP*T)-3')

(1)

DNA (5'-D(*CP*GP*GP*CP*AP*GP*T)-3')

(1)

DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*(2DT))-3')

(1)

DNA (5'-D(*DCP*DAP*DGP*DTP*DAP*DC)-3')

(1)

DNA (5'-D(*DCP*DGP*DGP*DCP*DAP*DAP*DTP*DAP*DCP*DTP*DG)-3')

(1)

DNA (5'-D(*DCP*DGP*DGP*DCP*DCP*DGP*DTP*DAP*DCP*DTP*DG)-3')

(1)

DNA (5'-D(P*GP*CP*CP*GP*CP*GP*TP*A)-3')

(1)

DNA repair protein REV1

(1)

DOWNSTREAM PRIMER DNA (5'-D(P*GP*CP*CP*G)-3')

(1)

Importin subunit alpha-1

(1)

PRIMER DNA (5'-D(*CP*AP*GP*TP*AP*(DOC))-3')

(1)

TEMPLATE DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3')

(1)

Interacting ligands  (36)

NA : SODIUM ION

(68)

MG : MAGNESIUM ION

(51)

EDO : 1,2-ETHANEDIOL

(34)

PPV : PYROPHOSPHATE

(23)

CL : CHLORIDE ION

(14)

MN : MANGANESE (II) ION

(14)

CA : CALCIUM ION

(11)

DUP : 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE

(10)

TTP : THYMIDINE-5'-TRIPHOSPHATE

(10)

SO4 : SULFATE ION

(9)

DCP : 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

(8)

D3T : 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE

(6)

GOL : GLYCEROL

(6)

ACT : ACETATE ION

(4)

CIT : CITRIC ACID

(4)

1GC : 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine

(3)

DTP : 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE

(3)

PO4 : PHOSPHATE ION

(3)

CAC : CACODYLATE ION

(2)

DGT : 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

(2)

SRT : S,R MESO-TARTARIC ACID

(2)

TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL

(2)

1RY : [[(2R,5S)-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate

(1)

1RZ : Lamivudine Triphosphate

(1)

1S0 : 4-amino-1-{2-deoxy-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-L-erythro-pentofuranosyl}pyrimidin-2(1H)-one

(1)

8DG : 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

(1)

DCT : 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE

(1)

DOC : 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE

(1)

EQ7 : 8-chloro-2-[(2,4-dichlorophenyl)amino]-3-(3-methylbutanoyl)-5-nitroquinolin-4(1H)-one

(1)

F2A : 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine

(1)

FMT : FORMIC ACID

(1)

GTF : 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate)

(1)

K : POTASSIUM ION

(1)

OXL : OXALATE ION

(1)

YQS : [[(2~{R},3~{S},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-sulfanyl-phosphoryl] phosphono hydrogen phosphate

(1)

ZAN : 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine

(1)

EC number / name  (1)

2.7.7.7 : DNA-directed DNA polymerase

(92)

Biological function  (4)

DNA binding

(86)

DNA-directed DNA polymerase activity

(86)

DNA polymerase activity

(85)

nucleotidyltransferase activity

(80)

Biological process  (1)

DNA repair

(86)

SCOP fold  (2)

SAM domain-like

(17)

Nucleotidyltransferase

(16)

SCOP family  (3)

DNA polymerase beta, N-terminal domain-like

(17)

DNA polymerase beta-like

(16)

DNA polymerase beta-like, second domain

(16)

CATH class  (2)

Alpha Beta

(56)

Mainly Alpha

(56)

CATH topology  (4)

DNA polymerase; domain 1

(56)

Beta Polymerase; domain 2

(55)

Beta Polymerase; domain 3

(55)

Rossmann fold

(1)

Pfam accession / name  (5)

PF14716 : HHH_8

(86)

PF10391 : DNA_pol_lambd_f

(85)

PF14791 : DNA_pol_B_thumb

(85)

PF14792 : DNA_pol_B_palm

(85)

PF16727 : REV1_C

(2)

Diffraction protocol  (1)

Single wavelength

(90)

Diffraction radiation source type  (2)

Synchrotron

(67)

Rotating anode

(22)

Diffraction source  (17)

APS BEAMLINE 22-ID

(39)

RIGAKU MICROMAX-007 HF

(12)

RIGAKU

(7)

NSRRC BEAMLINE BL13B1

(5)

APS BEAMLINE 22-BM

(3)

APS BEAMLINE 31-ID

(3)

NSLS BEAMLINE X29A

(3)

NSRRC BEAMLINE BL15A1

(3)

NSLS BEAMLINE X25

(2)

NSLS BEAMLINE X6A

(2)

RIGAKU RUH3R

(2)

SPRING-8 BEAMLINE BL44XU

(2)

SSRL BEAMLINE BL14-1

(2)

ALS BEAMLINE 5.0.2

(1)

NSRRC BEAMLINE BL13C1

(1)

OTHER

(1)

RIGAKU RU300

(1)

Synchrotron site  (6)

APS

(45)

NSRRC

(9)

NSLS

(7)

SPring-8

(2)

SSRL

(2)

ALS

(1)

Diffraction detector type  (3)

CCD

(64)

Pixel

(15)

Image plate

(10)

Refinement software  (4)

PHENIX

(62)

CNS

(22)

REFMAC

(4)

BUSTER

(1)

NMR software packages  (11)

CYANA

(2)

NMRPipe

(2)

NMRView

(2)

TALOS

(2)

ARIA

(1)

CNS

(1)

PROCHECK / PROCHECK-NMR

(1)

Sparky

(1)

VNMR

(1)

VnmrJ

(1)

Xplor-NIH

(1)

NMR Field Strength

400.0 - 500

(1)

500.0 - 600

(3)

600.0 - 700

(2)

700.0 - 800

(1)

800.0 - 900

(1)

Representative Structures

100%

95%

90%

70%

50%

40%

30%