Entry status  (1)

REL

(29)

Experimental methods  (1)

X-ray diffraction

(29)

Authors  (177)

Baumli S

(15)

Endicott JA

(12)

Hole AJ

(11)

Noble ME

(9)

Fischer PM

(5)

Huang S

(5)

Noble MEM

(5)

Pepper C

(5)

Shao H

(5)

Shi S

(5)

Wang S

(5)

Johnson LN

(4)

Schulze-Gahmen U

(4)

Babayeva ND

(3)

Bullock AN

(3)

Debreczeni JE

(3)

Knapp S

(3)

Lolli G

(3)

Lowe ED

(3)

Price DH

(3)

Rusconi L

(3)

Tahirov TH

(3)

Troiani S

(3)

Zhou Q

(3)

Alber T

(2)

Barlaam B

(2)

Collie GW

(2)

Cooper JJ

(2)

De Savi C

(2)

Dishington A

(2)

Drew L

(2)

Ferguson AD

(2)

Ferguson D

(2)

Gu C

(2)

Hande S

(2)

Hawkins J

(2)

Hird AW

(2)

Holmes J

(2)

Hurley JH

(2)

Lamb ML

(2)

Lu H

(2)

McGuire TM

(2)

Moore JE

(2)

O'Connell N

(2)

Pike KG

(2)

Sarkar U

(2)

Sedore SC

(2)

Shao W

(2)

Stead D

(2)

Varnes JG

(2)

Varzavand K

(2)

Vasbinder MM

(2)

Wang L

(2)

Wang LZ

(2)

Wu L

(2)

Yang B

(2)

Yao T

(2)

Abbas AY

(1)

Abou-Gharbia M

(1)

Anand K

(1)

Bai Y

(1)

Bao K

(1)

Baranovskiy AG

(1)

Baunbak D

(1)

Baunbæk D

(1)

Ben-Neriah Y

(1)

Ben-neriah Y

(1)

Benard J

(1)

Bettayeb K

(1)

Birnberg A

(1)

Bischofberger N

(1)

Brachya G

(1)

Burstain I

(1)

Bénard J

(1)

Casella R

(1)

Childers W

(1)

Chou S

(1)

Cidado J

(1)

Cook C

(1)

Day MAL

(1)

Delehouze C

(1)

Donald CS

(1)

Douc-Rasy S

(1)

Doudna JA

(1)

Echeverria I

(1)

Elias S

(1)

Endicott JE

(1)

Erdman PE

(1)

Ferguson A

(1)

Fink A

(1)

Foley DW

(1)

Freeman D

(1)

Freeman DB

(1)

Fujinaga K

(1)

Fung L

(1)

Galons H

(1)

Gao H

(1)

Geyer M

(1)

Glossop S

(1)

Grebe T

(1)

 

More...

Homo / hetero assembly  (2)

hetero

(28)

homo

(1)

Assembly composition  (3)

protein/protein complex

(26)

RNA/protein complex

(2)

protein structure

(1)

Assembly polymer count  (4)

dimer

(21)

tetramer

(3)

trimer

(3)

pentamer

(2)

Resolution distribution

2.0 - 2.5

(2)

2.5 - 3

(12)

3.0 - 3.5

(11)

3.5 - 4

(3)

5.5 - 6

(1)

Release year distribution

2005 - 2010

(7)

2010 - 2015

(17)

2015 - 2020

(4)

2020 - 2025

(5)

Journal  (13)

J Med Chem

(8)

ACS Chem Biol

(3)

EMBO J

(3)

Elife

(3)

Nature

(2)

Structure

(2)

To be published

(2)

Cell

(1)

Cell Cycle

(1)

Chem Biol

(1)

Genes Cancer

(1)

J Mol Biol

(1)

Proc Natl Acad Sci U S A

(1)

Organism superkingdom  (2)

Eukaryota

(29)

Viruses

(1)

Organism name  (2)

Homo sapiens

(29)

Equine infectious anemia virus

(1)

Molecule name  (7)

CycT1

(29)

Cyclin-T

(29)

Cyclin-T1

(29)

E-Tat

(1)

Protein Tat

(1)

Transactivating regulatory protein

(1)

eTat

(1)

Molecule type  (1)

Protein

(29)

Gene names  (2)

CCNT1

(29)

tat

(1)

Interacting Molecules  (5)

Cyclin-dependent kinase 9

(28)

Protein Tat

(6)

AF4/FMR2 family member 4

(5)

RNA (5'-R(P*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*U)-3')

(1)

RNA (5'-R(P*AP*UP*CP*UP*GP*AP*GP*CP*CP*UP*GP*GP*GP*AP*GP*CP*U)-3')

(1)

Interacting ligands  (6)

ZN : ZINC ION

(6)

GOL : GLYCEROL

(5)

PO4 : PHOSPHATE ION

(4)

TRS : 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL

(3)

SO4 : SULFATE ION

(1)

YT3 : YTTRIUM (III) ION

(1)

Biological function  (12)

cyclin-dependent protein serine/threonine kinase regulator activity

(29)

7SK snRNA binding

(1)

DNA binding

(1)

DNA-binding transcription factor binding

(1)

RNA polymerase binding

(1)

chromatin binding

(1)

cyclin-dependent protein serine/threonine kinase activator activity

(1)

molecular condensate scaffold activity

(1)

protein binding

(1)

protein kinase binding

(1)

snRNA binding

(1)

transcription cis-regulatory region binding

(1)

Biological process  (9)

regulation of transcription by RNA polymerase II

(29)

cell division

(1)

positive regulation by host of viral transcription

(1)

positive regulation of DNA-templated transcription, elongation

(1)

positive regulation of transcription by RNA polymerase II

(1)

positive regulation of transcription elongation by RNA polymerase II

(1)

regulation of cyclin-dependent protein serine/threonine kinase activity

(1)

response to xenobiotic stimulus

(1)

transcription by RNA polymerase II

(1)

Biological cell component  (7)

P-TEFb complex

(1)

cyclin-dependent protein kinase holoenzyme complex

(1)

cyclin/CDK positive transcription elongation factor complex

(1)

cytosol

(1)

nucleolus

(1)

nucleoplasm

(1)

nucleus

(1)

SCOP fold  (1)

Cyclin-like

(4)

SCOP family  (1)

Cyclin

(4)

CATH class  (1)

Mainly Alpha

(23)

CATH topology  (1)

Cyclin A; domain 1

(23)

Pfam accession / name  (3)

PF00134 : Cyclin_N

(29)

PF21797 : CycT2-like_C

(29)

PF00539 : Tat

(1)

Diffraction protocol  (1)

Single wavelength

(29)

Diffraction radiation source type  (2)

Synchrotron

(28)

Rotating anode

(1)

Diffraction source  (15)

ALS BEAMLINE 8.3.1

(4)

ESRF BEAMLINE ID29

(4)

DIAMOND BEAMLINE I03

(3)

ESRF BEAMLINE ID14-4

(3)

APS BEAMLINE 17-ID

(2)

APS BEAMLINE 24-ID-C

(2)

DIAMOND BEAMLINE I02

(2)

DIAMOND BEAMLINE I24

(2)

APS BEAMLINE 24-ID-E

(1)

ESRF BEAMLINE ID14-2

(1)

ESRF BEAMLINE ID23-1

(1)

ESRF BEAMLINE MASSIF-1

(1)

NSLS-II BEAMLINE 17-ID-1

(1)

RIGAKU

(1)

SPRING-8 BEAMLINE BL41XU

(1)

Synchrotron site  (6)

ESRF

(10)

Diamond

(7)

APS

(5)

ALS

(4)

NSLS-II

(1)

SPring-8

(1)

Diffraction detector type  (2)

CCD

(19)

Pixel

(10)

Refinement software  (5)

PHENIX

(14)

REFMAC

(8)

CNS

(4)

BUSTER

(2)

SHELXL-97

(1)

Representative Structures

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