Entry status  (1)

REL

(31)

Experimental methods  (2)

Electron Microscopy

(27)

X-ray diffraction

(4)

Authors  (161)

Conigrave AD

(10)

Fan QR

(10)

Skiniotis G

(10)

Zuo H

(10)

Clarke OB

(8)

Eng E

(8)

Frangaj A

(8)

Gao Y

(8)

Grassucci R

(8)

Hendrickson WA

(8)

Mathiesen JM

(8)

Park J

(8)

Rahman SN

(8)

Robertson MJ

(8)

Seven AB

(8)

Zhang Z

(8)

Geng Y

(7)

Wang L

(7)

Ling S

(6)

Ling SL

(6)

Meng X

(6)

Meng XY

(6)

Shi C

(6)

Shi P

(6)

Tian C

(6)

Tian CL

(6)

Wu C

(6)

Wu CG

(6)

Zhang C

(6)

Zhou Y

(6)

Asher WB

(5)

Cao B

(5)

Grasucci R

(5)

Hu G

(5)

Hu GB

(5)

Javitch JA

(5)

Lin X

(5)

Lu G

(5)

Lu Z

(5)

Manning JJ

(5)

Mendez J

(5)

Mosyak L

(5)

Ye J

(5)

Brauner-Osborne H

(4)

Bräuner-Osborne H

(4)

Chang S

(4)

Gu TJ

(4)

Hannan FM

(4)

He F

(4)

Li L

(4)

Liu L

(4)

Liu S

(4)

Liu SL

(4)

Meyerowitz JG

(4)

Panova O

(4)

Papasergi-Scott MM

(4)

Shi CW

(4)

Sun D

(4)

Sun DM

(4)

Sun W

(4)

Thakker RV

(4)

Zaoralova M

(4)

Zaoralová M

(4)

Zhang L

(4)

Zhang X

(4)

Carragher B

(3)

Chen S

(3)

Dandey VP

(3)

Frank J

(3)

Fu Z

(3)

Graziano J

(3)

Kloss B

(3)

Lee Y

(3)

Liu J

(3)

Liu Z

(3)

Potter CS

(3)

Ray KM

(3)

Slavkovich VN

(3)

Tan YZ

(3)

Vallese F

(3)

Yen LY

(3)

Brennan SC

(2)

Brown AP

(2)

Brown EM

(2)

Bush M

(2)

Chang D

(2)

Chang DD

(2)

Chang W

(2)

Chen X

(2)

Chen XC

(2)

Chen Y

(2)

Cheng TC

(2)

Cheng Z

(2)

Colecraft HM

(2)

Conigrave A

(2)

Cui Q

(2)

Cui QQ

(2)

Dai M

(2)

Ding Z

(2)

Ding ZY

(2)

 

More...

Homo / hetero assembly  (2)

homo

(16)

hetero

(15)

Assembly composition  (3)

protein structure

(16)

protein/protein complex

(14)

D-protein/protein complex

(1)

Assembly polymer count  (5)

dimer

(19)

pentamer

(6)

tetramer

(3)

hexamer

(2)

heptamer

(1)

Resolution distribution

2.0 - 2.5

(2)

2.5 - 3

(10)

3.0 - 3.5

(8)

3.5 - 4

(6)

4.0 - 4.5

(3)

5.5 - 6

(2)

Release year distribution

2015 - 2020

(4)

2020 - 2025

(27)

2025 - 2030

(1)

Journal  (7)

Nature

(13)

Cell Res

(6)

Elife

(4)

Proc Natl Acad Sci U S A

(3)

Sci Adv

(2)

Science

(2)

Sci Rep

(1)

Organism superkingdom  (1)

Eukaryota

(31)

Organism name  (1)

Homo sapiens

(31)

Molecule name  (6)

CaR

(31)

CaSR

(31)

Extracellular calcium-sensing receptor

(31)

PCaR1

(31)

Parathyroid cell calcium-sensing receptor 1

(31)

hCasR

(31)

Molecule type  (1)

Protein

(31)

Gene names  (3)

CASR

(31)

GPRC2A

(31)

PCAR1

(31)

Interacting Molecules  (15)

Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

(9)

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

(8)

Extracellular calcium-sensing receptor

(5)

Guanine nucleotide-binding protein G(i) subunit alpha-1

(5)

Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

(4)

Guanine nucleotide-binding protein G(i) subunit alpha-3

(3)

Single-chain antibody fragment scFv16

(2)

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

(1)

Guanine nucleotide-binding protein G(i) subunit alpha-2

(1)

Guanine nucleotide-binding protein G(q) subunit alpha

(1)

NB-2D11

(1)

Nanobody Nb-35

(1)

ScFv16

(1)

etelcalcetide

(1)

gamma-glutamyl-valyl-glycine

(1)

Interacting ligands  (23)

NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose

(28)

CA : CALCIUM ION

(22)

PO4 : PHOSPHATE ION

(21)

TRP : TRYPTOPHAN

(14)

TCR : CYCLOMETHYLTRYPTOPHAN

(10)

CLR : CHOLESTEROL

(7)

9IG : 3-(2-chlorophenyl)-N-[(1R)-1-(3-methoxyphenyl)ethyl]propan-1-amine

(6)

YP4 : N-[(1R)-1-(naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine

(6)

Y01 : CHOLESTEROL HEMISUCCINATE

(4)

A1AF7 : (19R,22S,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate

(3)

PCW : 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

(3)

SPM : SPERMINE

(3)

YP1 : 2-chloro-6-[(2R)-2-hydroxy-3-{[2-methyl-1-(naphthalen-2-yl)propan-2-yl]amino}propoxy]benzonitrile

(3)

AV0 : Lauryl Maltose Neopentyl Glycol

(2)

BCT : BICARBONATE ION

(2)

CL : CHLORIDE ION

(2)

MG : MAGNESIUM ION

(2)

PRD_900017 : triacetyl-beta-chitotriose

(2)

A1ATP : (5R)-N-[2-(1,2-benzothiazol-3-yl)ethyl]-1-methyl-2,3,4,5-tetrahydro-1H-1-benzazepin-5-amine

(1)

A1ATX : (1R)-1-(2H-1,3-benzodioxol-4-yl)-N-[2-(1,2-benzothiazol-3-yl)ethyl]ethan-1-amine

(1)

GD3 : GADOLINIUM ION

(1)

H43 : 2-[4-[(3S)-3-[[(1R)-1-naphthalen-1-ylethyl]amino]pyrrolidin-1-yl]phenyl]ethanoic acid

(1)

SO4 : SULFATE ION

(1)

Biological function  (10)

G protein-coupled receptor activity

(30)

amino acid binding

(4)

calcium ion binding

(4)

integrin binding

(4)

metal ion binding

(4)

phosphatidylinositol-4,5-bisphosphate phospholipase C activity

(4)

protein binding

(4)

protein homodimerization activity

(4)

protein kinase binding

(4)

transmembrane transporter binding

(4)

Biological process  (35)

G protein-coupled receptor signaling pathway

(30)

JNK cascade

(4)

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

(4)

anatomical structure morphogenesis

(4)

bile acid secretion

(4)

branching morphogenesis of an epithelial tube

(4)

calcium ion import

(4)

cellular response to glucose stimulus

(4)

cellular response to hepatocyte growth factor stimulus

(4)

cellular response to hypoxia

(4)

cellular response to low-density lipoprotein particle stimulus

(4)

cellular response to peptide

(4)

cellular response to vitamin D

(4)

chemosensory behavior

(4)

chloride transmembrane transport

(4)

detection of calcium ion

(4)

fat pad development

(4)

intracellular calcium ion homeostasis

(4)

ossification

(4)

phospholipase C-activating G protein-coupled receptor signaling pathway

(4)

positive regulation of ERK1 and ERK2 cascade

(4)

positive regulation of calcium ion import

(4)

positive regulation of cell population proliferation

(4)

positive regulation of gene expression

(4)

positive regulation of insulin secretion

(4)

positive regulation of positive chemotaxis

(4)

positive regulation of vasoconstriction

(4)

regulation of calcium ion transport

(4)

regulation of presynaptic membrane potential

(4)

response to calcium ion

(4)

response to fibroblast growth factor

(4)

response to ischemia

(4)

response to metal ion

(4)

signal transduction

(4)

vasodilation

(4)

Biological cell component  (10)

membrane

(30)

apical plasma membrane

(4)

axon

(4)

axon terminus

(4)

basolateral plasma membrane

(4)

cell surface

(4)

glutamatergic synapse

(4)

neuronal cell body

(4)

plasma membrane

(4)

presynaptic membrane

(4)

CATH class  (1)

Alpha Beta

(3)

CATH topology  (1)

Rossmann fold

(3)

Pfam accession / name  (3)

PF01094 : ANF_receptor

(31)

PF07562 : NCD3G

(29)

PF00003 : 7tm_3

(27)

Diffraction protocol  (1)

Single wavelength

(4)

Diffraction radiation source type  (1)

Synchrotron

(4)

Diffraction source  (2)

APS BEAMLINE 21-ID-D

(2)

APS BEAMLINE 24-ID-C

(2)

Synchrotron site  (1)

APS

(4)

Diffraction detector type  (2)

CCD

(2)

Pixel

(2)

Refinement software  (4)

PHENIX

(11)

BUSTER

(2)

REFMAC

(2)

phenix.real_space_refine

(2)

EM microscope model  (3)

FEI TITAN KRIOS

(25)

JEOL CRYO ARM 300

(1)

TFS KRIOS

(1)

EM detector name  (3)

GATAN K3 BIOQUANTUM (6k x 4k)

(15)

GATAN K3 (6k x 4k)

(7)

GATAN K2 SUMMIT (4k x 4k)

(5)

Representative Structures

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