Entry status  (1)

REL

(4)

Experimental methods  (1)

X-ray diffraction

(4)

Authors  (18)

Hoeoeg JO

(3)

Höög JO

(3)

Sandalova T

(3)

Schneider G

(3)

Svensson S

(3)

Hoog JO

(2)

Arrowsmith CH

(1)

Bishop S

(1)

Bountra C

(1)

Edwards AM

(1)

Kavanagh KL

(1)

Murray J

(1)

Oppermann U

(1)

Roos A

(1)

Shafqat N

(1)

Structural Genomics Consortium (SGC)

(1)

Yue W

(1)

von Delft F

(1)

Homo / hetero assembly  (1)

homo

(4)

Assembly composition  (1)

protein structure

(4)

Assembly polymer count  (1)

dimer

(4)

Resolution distribution

2.0 - 2.5

(4)

Release year distribution

1995 - 2000

(3)

2000 - 2005

(3)

2005 - 2010

(1)

Journal  (2)

J Mol Biol

(3)

To be published

(1)

Organism superkingdom  (1)

Eukaryota

(4)

Organism name  (2)

Mus musculus

(3)

Homo sapiens

(1)

Molecule name  (7)

Alcohol dehydrogenase 2

(4)

Alcohol dehydrogenase 4

(4)

All-trans-retinol dehydrogenase [NAD(+)] ADH4

(4)

ADH2

(3)

Alcohol dehydrogenase II

(3)

Alcohol dehydrogenase class II

(3)

Alcohol dehydrogenase class II pi chain

(1)

Molecule type  (1)

Protein

(4)

Gene names  (4)

Adh2

(3)

Adh4

(3)

ADH2

(1)

ADH4

(1)

Interacting ligands  (6)

ZN : ZINC ION

(4)

NAD : NICOTINAMIDE-ADENINE-DINUCLEOTIDE

(2)

NAI : 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

(2)

ACY : ACETIC ACID

(1)

CXF : CYCLOHEXYLFORMAMIDE

(1)

EDO : 1,2-ETHANEDIOL

(1)

EC number / name  (1)

1.1.1.105 : All-trans-retinol dehydrogenase (NAD(+))

(4)

Biological function  (13)

NAD binding

(4)

NADPH:quinone reductase activity

(4)

alcohol dehydrogenase (NAD+) activity

(4)

aldose reductase (NADPH) activity

(4)

all-trans retinal binding

(4)

all-trans-retinol dehydrogenase (NAD+) activity

(4)

benzaldehyde dehydrogenase (NAD+) activity

(4)

metal ion binding

(4)

oxidoreductase activity

(4)

retinol binding

(4)

zinc ion binding

(4)

S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity

(1)

protein binding

(1)

Biological process  (11)

alcohol catabolic process

(4)

alcohol metabolic process

(4)

aldehyde metabolic process

(4)

ethanol metabolic process

(4)

fatty acid omega-oxidation

(4)

lipid metabolic process

(4)

quinone metabolic process

(4)

retinoid metabolic process

(4)

retinol metabolic process

(4)

small molecule catabolic process

(3)

formaldehyde catabolic process

(1)

Biological cell component  (3)

cytoplasm

(4)

cytosol

(4)

nucleoplasm

(4)

Compound cofactor class  (1)

Nicotinamide-adenine dinucleotide

(4)

SCOP fold  (2)

GroES-like

(3)

NAD(P)-binding Rossmann-fold domains

(3)

SCOP family  (2)

Alcohol dehydrogenase-like, C-terminal domain

(3)

Alcohol dehydrogenase-like, N-terminal domain

(3)

CATH class  (1)

Alpha Beta

(4)

CATH topology  (2)

Quinone Oxidoreductase; Chain A, domain 1

(4)

Rossmann fold

(4)

Pfam accession / name  (2)

PF00107 : ADH_zinc_N

(4)

PF08240 : ADH_N

(4)

Representative Structures

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