Uniprot accession / id : Q9QZK2  OR   Uniprot accession / id : O75815
 
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Entry Information
Entry status  (1)
REL
(1)
 
Experimental methods  (1)
X-ray diffraction
(1)
 
Authors  (7)
Dobaczewska MK
(1)
Lee JJ
(1)
Mace PD
(1)
Pasquale EB
(1)
Riedl SJ
(1)
Robinson H
(1)
Wallez Y
(1)
 
Homo / hetero assembly  (1)
homo
(1)
 
Assembly composition  (1)
protein structure
(1)
 
Assembly polymer count  (1)
dimer
(1)
 
Resolution distribution
2.0 - 2.5
(1)
 
Release year distribution
2010 - 2015
(1)
 
Journal  (1)
Nat Struct Mol Biol
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(1)
 
Organism name  (1)
Homo sapiens
(1)
 
Molecule name  (3)
Breast cancer anti-estrogen resistance protein 3
(1)
Novel SH2-containing protein 2
(1)
SH2 domain-containing protein 3B
(1)
 
Molecule type  (1)
Protein
(1)
 
Gene names  (4)
BCAR3
(1)
NSP2
(1)
SH2D3B
(1)
UNQ271/PRO308
(1)
 
Interacting ligands  (1)
POG : (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL
(1)
 
Function and Biology
Biological function  (1)
guanyl-nucleotide exchange factor activity
(1)
 
Biological process  (1)
small GTPase-mediated signal transduction
(1)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(1)
 
CATH topology  (1)
Son of Sevenless (SoS) protein; Chain S, domain 2
(1)
 
Pfam accession / name  (1)
PF00617 : RasGEF
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(1)
 
Diffraction radiation source type  (1)
Rotating anode
(1)
 
Diffraction source  (1)
RIGAKU FR-E SUPERBRIGHT
(1)
 
Diffraction detector type  (1)
Image plate
(1)
 
Refinement software  (1)
PHENIX
(1)
 
Representative Structures
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Structure of the C-terminal domain of BCAR3
Mace PD, Robinson H, Riedl SJ
Nat Struct Mol Biol (2011) [PMID: 22081014  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: POG    POG   
Assembly name: Breast cancer anti-estrogen resistance protein 3 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-131126 (Preferred)   search this ID
PDBe-KB: O75815   
X-ray diffraction
2.4Å resolution
Released: 23 Nov 2011
Model geometry
Fit model/data
3t6a
3t6a
3t6a
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