Uniprot accession / id : Q9R049  OR   Uniprot accession / id : Q9UKV5
 
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Entry Information
Entry status  (1)
REL
(13)
 
Experimental methods  (2)
Solution NMR
(7)
X-ray diffraction
(6)
 
Authors  (45)
Byrd RA
(8)
Das R
(8)
Li J
(8)
Tarasov SG
(8)
Weissman AM
(8)
Huang T
(7)
King A
(7)
Ji X
(5)
Chen Y
(4)
Liu S
(4)
Mariano J
(4)
Tarasov S
(4)
Liang YH
(3)
Byrd R
(2)
Linag Y
(2)
Weissman A
(2)
Altieri AS
(1)
Brunger AT
(1)
Gehring K
(1)
Ghirlando R
(1)
Haenzelmann P
(1)
Hanzelmann P
(1)
Hayashi F
(1)
Hirota H
(1)
Hänzelmann P
(1)
Kalathur RC
(1)
Kitasaka S
(1)
Kostova Z
(1)
Kozlov G
(1)
LePage K
(1)
Li L
(1)
Li W
(1)
Liang Y-H
(1)
McFeeters RL
(1)
RIKEN Structural Genomics/Proteomics Initiative (RSGI)
(1)
Ruhul Momen AZM
(1)
Schindelin H
(1)
Shaw GX
(1)
Shi G
(1)
Tsai YC
(1)
Tu D
(1)
Wang C
(1)
Wollert T
(1)
Ye Y
(1)
Yokoyama S
(1)
 
Homo / hetero assembly  (2)
hetero
(9)
homo
(4)
 
Assembly composition  (2)
protein/protein complex
(9)
protein structure
(4)
 
Assembly polymer count  (3)
dimer
(6)
monomer
(4)
trimer
(3)
 
Resolution distribution
1.5 - 2
(4)
2.0 - 2.5
(1)
2.5 - 3
(1)
 
Release year distribution
2005 - 2010
(3)
2010 - 2015
(9)
2020 - 2025
(1)
 
Journal  (6)
Structure
(4)
EMBO J
(3)
To be published
(3)
J Biol Chem
(1)
Mol Cell
(1)
Proc Natl Acad Sci U S A
(1)
 
Representative Structures
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Entries 1 to 10 of 13
Entries 1 to 10 of 13
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Crystal structure of UBE2G2 adduct with phenethyl isothiocyanate (PEITC) at the Cys48 position
Wang C, Shaw GX, Shi G, Ji X
To be published
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: EDO   
Modified residues: 6M6    6M6   
Assembly name: E3 ubiquitin-protein ligase AMFR and Ubiquitin-conjugating enzyme E2 G2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-158052 (Preferred)   search this ID
PDBe-KB: Q9UKV5    P60604   
X-ray diffraction
1.95Å resolution
Released: 5 Jun 2024
Model geometry
Fit model/data
8t0s
8t0s
8t0s
Solution structure of RUH-076, a human CUE domain
Ruhul Momen AZM, Kitasaka S, Hirota H, Hayashi F, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: E3 ubiquitin-protein ligase AMFR (Preferred)   search this complex
PDBe complex ID: PDB-CPX-193863 (Preferred)   search this ID
PDBe-KB: Q9UKV5   
Solution NMR
Released: 25 Sep 2007
Model geometry
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Data not analysed
2ejs
2ejs
2ejs
gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin
Liu S, Chen Y, Huang T, Tarasov SG, King A, Li J, Weissman AM, Byrd RA, Das R
Structure (2012) [PMID: 23123110  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: E3 ubiquitin-protein ligase AMFR and Ubiquitin (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143443 (Preferred)   search this ID
PDBe-KB: Q9UKV5    P0CG48   
Solution NMR
Released: 21 Nov 2012
Model geometry
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Data not analysed
2lvq
2lvq
2lvq
Structure of the gp78 CUE domain
Liu S, Chen Y, Huang T, Tarasov SG, King A, Li J, Weissman AM, Byrd RA, Das R
Structure (2012) [PMID: 23123110  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: E3 ubiquitin-protein ligase AMFR (Preferred)   search this complex
PDBe complex ID: PDB-CPX-193863 (Preferred)   search this ID
PDBe-KB: Q9UKV5   
Solution NMR
Released: 21 Nov 2012
Model geometry
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Data not analysed
2lvn
2lvn
2lvn
Crystal Structure of the Ube2g2:RING-G2BR complex
Liang Y-H, Li J, Das R, Byrd RA, Ji X
EMBO J (2013) [PMID: 23942235  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: ZN    ZN    OXL   
Assembly name: E3 ubiquitin-protein ligase AMFR and Ubiquitin-conjugating enzyme E2 G2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-158052 (Preferred)   search this ID
PDBe-KB: Q9UKV5    P60604   
X-ray diffraction
2.3Å resolution
Released: 28 Aug 2013
Model geometry
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4lad
4lad
4lad
Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution
Kalathur RC, Das R, Li J, Byrd RA, Ji X
Mol Cell (2009) [PMID: 19560420  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: E3 ubiquitin-protein ligase AMFR and Ubiquitin-conjugating enzyme E2 G2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-158052 (Preferred)   search this ID
PDBe-KB: Q9UKV5    P60604   
X-ray diffraction
1.8Å resolution
Released: 14 Jul 2009
Model geometry
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3h8k
3h8k
3h8k
Crystal structure of p97N in complex with the C-terminus of gp78
Haenzelmann P, Schindelin H
J Biol Chem (2011) [PMID: 21914798  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: CL   
Assembly name: E3 ubiquitin-protein ligase AMFR and Transitional endoplasmic reticulum ATPase (Preferred)   search this complex
PDBe complex ID: PDB-CPX-157176 (Preferred)   search this ID
PDBe-KB: Q9UKV5    P55072   
X-ray diffraction
1.802Å resolution
Released: 14 Sep 2011
Model geometry
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3tiw
3tiw
3tiw
Crystal structure of the CUE domain of the E3 ubiquitin ligase AMFR (gp78)
Kozlov G, LePage K, Gehring K
To be published
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: E3 ubiquitin-protein ligase AMFR (Preferred)   search this complex
PDBe complex ID: PDB-CPX-193863 (Preferred)   search this ID
PDBe-KB: Q9UKV5   
X-ray diffraction
1.6Å resolution
Released: 25 Jul 2012
Model geometry
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4g3o
4g3o
4g3o
Structure of the gp78CUE domain bound to monubiquitin
Liu S, Chen Y, Huang T, Tarasov SG, King A, Li J, Weissman AM, Byrd RA, Das R
Structure (2012) [PMID: 23123110  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: E3 ubiquitin-protein ligase AMFR and Ubiquitin (Preferred)   search this complex
PDBe complex ID: PDB-CPX-143411 (Preferred)   search this ID
PDBe-KB: Q9UKV5    P0CG48   
Solution NMR
Released: 21 Nov 2012
Model geometry
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Data not analysed
2lvo
2lvo
2lvo
NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g
Das R, Linag Y, Mariano J, Li J, Huang T, King A, Weissman A, Ji X, Byrd R
EMBO J (2013) [PMID: 23942235  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Bound ligands: ZN    ZN   
Assembly name: E3 ubiquitin-protein ligase AMFR and Ubiquitin-conjugating enzyme E2 G2 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-158053 (Preferred)   search this ID
PDBe-KB: Q9UKV5    P60604   
Solution NMR
Released: 28 Aug 2013
Model geometry
Fit model/data
Data not analysed
2lxp
2lxp
2lxp
Entries 1 to 10 of 13
Entries 1 to 10 of 13