Entry status  (1)

REL

(6)

Experimental methods  (2)

Electron Microscopy

(5)

X-ray diffraction

(1)

Authors  (34)

Chen Y

(2)

Gates SN

(2)

Gestwicki JE

(2)

Hang Y

(2)

Lee K

(2)

Li G

(2)

Nadel CM

(2)

Southworth DR

(2)

Sun F

(2)

Thwin AC

(2)

Tse E

(2)

Wen Z

(2)

Wen ZL

(2)

Xie Q

(2)

Xu L

(2)

Zhai Y

(2)

Zhai YJ

(2)

Zhang B

(2)

Zhang L

(2)

Zhang Y

(2)

Zhao B

(2)

Zhao Q

(2)

Zhu Y

(2)

Agard DA

(1)

Felts SJ

(1)

Johnson JL

(1)

Noddings CM

(1)

Owen BA

(1)

Owen BAL

(1)

Sullivan WP

(1)

Toft DO

(1)

Wang RY

(1)

Wang Y-R

(1)

Weaver AJ

(1)

Homo / hetero assembly  (2)

hetero

(5)

homo

(1)

Assembly composition  (2)

protein/protein complex

(5)

protein structure

(1)

Assembly polymer count  (5)

tetramer

(2)

dimer

(1)

hexamer

(1)

pentamer

(1)

trimer

(1)

Resolution distribution

2.0 - 2.5

(1)

2.5 - 3

(1)

3.0 - 3.5

(4)

Release year distribution

1995 - 2000

(1)

2000 - 2005

(1)

2020 - 2025

(5)

Journal  (4)

Mol Cell

(2)

Structure

(2)

J Biol Chem

(1)

Nature

(1)

Organism superkingdom  (1)

Eukaryota

(6)

Organism name  (2)

Homo sapiens

(4)

Mus musculus

(2)

Molecule name  (7)

Cytosolic prostaglandin E2 synthase

(6)

Hsp90 co-chaperone

(6)

Progesterone receptor complex p23

(6)

Prostaglandin E synthase 3

(6)

Telomerase-binding protein p23

(6)

cPGES

(6)

Sid 3177

(2)

Molecule type  (1)

Protein

(6)

Gene names  (6)

P23

(4)

PTGES3

(4)

TEBP

(4)

Ptges3

(2)

Sid3177

(2)

Tebp

(2)

Interacting Molecules  (6)

Heat shock protein HSP 90-alpha

(3)

Aryl hydrocarbon receptor

(2)

Heat shock protein HSP 90-beta

(2)

AH receptor-interacting protein

(1)

Glucocorticoid receptor

(1)

Peptidyl-prolyl cis-trans isomerase FKBP5

(1)

Interacting ligands  (1)

SO4 : SULFATE ION

(1)

EC number / name  (1)

5.3.99.3 : Prostaglandin-E synthase

(6)

Biological function  (8)

Hsp90 protein binding

(6)

DNA polymerase binding

(5)

isomerase activity

(5)

prostaglandin-E synthase activity

(5)

unfolded protein binding

(5)

protein binding

(3)

protein-folding chaperone binding

(3)

telomerase activity

(3)

Biological process  (20)

fatty acid biosynthetic process

(5)

fatty acid metabolic process

(5)

lipid metabolic process

(5)

prostaglandin biosynthetic process

(5)

prostaglandin metabolic process

(5)

telomerase holoenzyme complex assembly

(5)

telomere maintenance via telomerase

(5)

chaperone cofactor-dependent protein refolding

(3)

chaperone-mediated protein complex assembly

(3)

positive regulation of telomere maintenance via telomerase

(3)

prostanoid biosynthetic process

(3)

protein folding

(3)

protein stabilization

(3)

signal transduction

(3)

telomere maintenance

(3)

fibroblast proliferation

(2)

glycogen biosynthetic process

(2)

lung saccule development

(2)

nuclear receptor-mediated glucocorticoid signaling pathway

(2)

skin development

(2)

Biological cell component  (8)

cytoplasm

(5)

chromosome, telomeric region

(3)

cytosol

(3)

nucleoplasm

(3)

nucleus

(3)

protein folding chaperone complex

(3)

protein-containing complex

(3)

telomerase holoenzyme complex

(3)

SCOP fold  (1)

HSP20-like chaperones

(1)

SCOP family  (1)

Co-chaperone p23-like

(1)

CATH class  (1)

Mainly Beta

(1)

CATH topology  (1)

Immunoglobulin-like

(1)

Pfam accession / name  (1)

PF04969 : CS

(6)

Diffraction protocol  (1)

Single wavelength

(1)

Diffraction radiation source type  (1)

Synchrotron

(1)

Diffraction source  (1)

CHESS BEAMLINE F1

(1)

Synchrotron site  (1)

CHESS

(1)

Diffraction detector type  (1)

CCD

(1)

Refinement software  (2)

PHENIX

(2)

CNS

(1)

EM microscope model  (1)

FEI TITAN KRIOS

(5)

EM detector name  (3)

GATAN K3 BIOQUANTUM (6k x 4k)

(3)

GATAN K2 SUMMIT (4k x 4k)

(2)

GATAN K3 (6k x 4k)

(2)

Representative Structures

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