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Entry Information
Entry status
(1)
Experimental methods
(1)
X-ray diffraction
(4)
Authors
(16)
Cusack S
(4)
Hemrika W
(4)
McCarthy AA
(4)
Gros P
(3)
Mccarthy AA
(3)
Morlot C
(3)
Romijn RA
(3)
Ravelli RB
(2)
Thielens NM
(2)
Bastmeyer M
(1)
Fritz M
(1)
Henry M
(1)
Jamin M
(1)
Lortat-Jacob H
(1)
Seiradake E
(1)
von Philipsborn AC
(1)
Homo / hetero assembly
(2)
homo
(3)
hetero
(1)
Assembly composition
(2)
protein structure
(3)
protein/protein complex
(1)
Assembly polymer count
(2)
dimer
(2)
monomer
(2)
Resolution distribution
1.5 - 2
(3)
3.0 - 3.5
(1)
Release year distribution
2005 - 2010
(4)
Journal
(3)
Proc Natl Acad Sci U S A
(2)
Acta Crystallogr D Biol Crystallogr
(1)
EMBO Rep
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Macromolecules
Organism superkingdom
(1)
Eukaryota
(4)
Organism name
(1)
Homo sapiens
(4)
Molecule name
(4)
Slit homolog 2 protein
(4)
Slit homolog 2 protein C-product
(4)
Slit homolog 2 protein N-product
(4)
Slit-2
(4)
Molecule type
(1)
Protein
(4)
Gene names
(2)
SLIL3
(4)
SLIT2
(4)
Interacting Molecules
(1)
Roundabout homolog 1
(1)
Interacting ligands
(4)
GOL : GLYCEROL
(1)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(1)
PEG : DI(HYDROXYETHYL)ETHER
(1)
SO4 : SULFATE ION
(1)
Function and Biology
Biological function
(1)
follicle-stimulating hormone receptor activity
(2)
Biological process
(1)
G protein-coupled receptor signaling pathway
(2)
Biological cell component
(1)
membrane
(2)
Sequence and Structure classification
CATH class
(1)
Alpha Beta
(4)
CATH topology
(1)
Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
(4)
Pfam accession / name
(3)
PF01463 : LRRCT
(4)
PF13855 : LRR_8
(4)
PF01462 : LRRNT
(3)
Experimental Information
Diffraction protocol
(1)
Single wavelength
(4)
Diffraction radiation source type
(1)
Synchrotron
(4)
Diffraction source
(2)
ESRF BEAMLINE ID14-4
(3)
ESRF BEAMLINE ID23-1
(1)
Synchrotron site
(1)
ESRF
(4)
Diffraction detector type
(1)
CCD
(4)
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REFMAC
(4)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 4 of 4
Select all entries on this page
Second LRR domain of human Slit2
Morlot C, Cusack S, McCarthy AA
Proc Natl Acad Sci U S A
(2007)
[PMID: 17848514 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Slit homolog 2 protein N-product
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131762 (Preferred)
search this ID
PDBe-KB:
O94813
Third LRR domain of human Slit2
Morlot C, Cusack S, McCarthy AA
Acta Crystallogr D Biol Crystallogr
(2007)
[PMID: 17704564 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Slit homolog 2 protein N-product
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131762 (Preferred)
search this ID
PDBe-KB:
O94813
The Human Slit 2 Dimerization Domain D4
Seiradake E, von Philipsborn AC, Henry M, Fritz M, Lortat-Jacob H, Jamin M, Hemrika W, Bastmeyer M, Cusack S, McCarthy AA
EMBO Rep
(2009)
[PMID: 19498462 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
SO4
Assembly name:
Slit homolog 2 protein N-product
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131764 (Preferred)
search this ID
PDBe-KB:
O94813
Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1
Morlot C, Cusack S, McCarthy AA
Proc Natl Acad Sci U S A
(2007)
[PMID: 17848514 ]
Source organism: Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Slit homolog 2 protein N-product and Roundabout homolog 1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-131763 (Preferred)
search this ID
Entries 1 to 4 of 4