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(39)
Ghosh G
(8)
Huang DB
(4)
Li T
(4)
Meshcheryakov VA
(4)
Pan W
(4)
Wang VY
(4)
Wang VY-F
(4)
Wang Y
(4)
Vu D
(3)
Forwood JK
(2)
Fusco A
(2)
Stewart M
(2)
Tsimbslyuk S
(2)
Bharath SR
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Bowler MW
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Cramer P
(1)
Duynne GV
(1)
Gupta K
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Hayashi F
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Larson CJ
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Li Y
(1)
Loo BZL
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Miller D
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Muller CW
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Müller CW
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Nagashima T
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Ozturk MB
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RIKEN Structural Genomics/Proteomics Initiative (RSGI)
(1)
Song H
(1)
Tao Z
(1)
Tao ZH
(1)
Tergaonkar V
(1)
Van Duyne GD
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Vemu A
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Verdine GL
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Ware CF
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Xu X
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Yokoyama S
(1)
Young Kim D
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Homo / hetero assembly
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hetero
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homo
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protein structure
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protein/protein complex
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tetramer
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monomer
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trimer
(1)
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2.0 - 2.5
(2)
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(6)
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(4)
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(1)
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Mus musculus
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(8)
DNA-binding factor KBF2
(13)
Nuclear factor NF-kappa-B p100 subunit
(13)
Nuclear factor NF-kappa-B p52 subunit
(13)
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
(13)
H2TF1
(11)
Lymphocyte translocation chromosome 10 protein
(11)
Lyt10
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Oncogene Lyt-10
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(13)
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LYT10
(11)
NFKB2
(11)
Nfkb2
(2)
Interacting Molecules
(17)
Importin subunit alpha-1
(2)
Transcription factor RelB
(2)
5'-D(*DCP*DGP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DCP*DC)-3'
(1)
DNA (5'-D(*AP*AP*GP*GP*GP*GP*GP*AP*GP*TP*CP*CP*CP*CP*TP*TP*G)-3')
(1)
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(1)
DNA (5'-D(*CP*AP*AP*GP*GP*GP*GP*AP*CP*TP*CP*CP*CP*CP*CP*TP*T)-3')
(1)
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(1)
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(1)
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(1)
DNA (5'-D(*GP*AP*AP*GP*GP*GP*GP*GP*TP*GP*AP*CP*CP*CP*CP*TP*TP*G)-3')
(1)
DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3')
(1)
DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3')
(1)
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(1)
DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3')
(1)
DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3')
(1)
Protein C-ets-1
(1)
bacterial peptide
(1)
Interacting ligands
(1)
SO4 : SULFATE ION
(2)
Function and Biology
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DNA-binding transcription factor activity
(9)
DNA binding
(7)
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regulation of DNA-templated transcription
(9)
signal transduction
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cytoplasm
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Sequence and Structure classification
SCOP fold
(2)
Common fold of diphtheria toxin/transcription factors/cytochrome f
(1)
Immunoglobulin-like beta-sandwich
(1)
SCOP family
(2)
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
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Mainly Beta
(5)
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(1)
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Immunoglobulin-like
(5)
Death Domain, Fas
(1)
Pfam accession / name
(4)
PF16179 : RHD_dimer
(9)
PF00554 : RHD_DNA_bind
(7)
PF00023 : Ank
(1)
PF00531 : Death
(1)
Experimental Information
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(12)
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(10)
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(8)
SSRF BEAMLINE BL17U1
(3)
AUSTRALIAN SYNCHROTRON BEAMLINE MX2
(2)
RIGAKU RU200
(2)
APS BEAMLINE 19-ID
(1)
APS BEAMLINE 24-ID-C
(1)
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(1)
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REFMAC
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CYANA
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VNMR
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NMR Field Strength
700.0 - 800
(1)
800.0 - 900
(1)
900.0 - 1000
(1)
Representative Structures
Representative Structures
Entries
Macromolecules
Compounds
Protein families
Entries 1 to 10 of 13
Select all entries on this page
Monopartite p52 NLS in complex with Importin alpha 2
Tsimbslyuk S, Stewart M, Forwood JK
To be published
Assembly composition: protein/protein complex
PDBe complex ID:
PDB-CPX-273854 (Preferred)
search this ID
Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2
Xu X, Bharath SR, Song H
Nat Commun
(2018)
[PMID: 30093619 ]
Source organism: Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
Nuclear factor NF-kappa-B p52 subunit and Protein C-ets-1 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-119521 (Preferred)
search this ID
Structure of NF-kB p52 homodimer bound to A/T-centric P-Selectin kB DNA fragment
Meshcheryakov VA, Wang VY-F
Elife
(2023)
[PMID: 36779700 ]
Source organism: Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
NF-kappaB transcription regulation complex, p52/p52 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-122243 (Preferred)
search this ID

Structure of NF-kB p52 homodimer bound to +1/-1 swap P-Selectin kB DNA fragment
Meshcheryakov VA, Wang VY-F
Elife
(2023)
[PMID: 36779700 ]
Source organism: Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
NF-kappaB transcription regulation complex, p52/p52 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-122242 (Preferred)
search this ID

Structure of NF-kB p52 homodimer bound to 13-mer A/T-centric P-Selectin kB DNA fragment
Meshcheryakov VA, Wang VY-F
Elife
(2023)
[PMID: 36779700 ]
Source organism: Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
NF-kappaB transcription regulation complex, p52/p52 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-122257 (Preferred)
search this ID

Structure of NF-kB p52 homodimer bound to P-Selectin kB DNA fragment
Meshcheryakov VA, Wang VY-F
Elife
(2023)
[PMID: 36779700 ]
Source organism: Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
NF-kappaB transcription regulation complex, p52/p52 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-275800 (Preferred)
search this ID

bipartite p52 NLS in complex with Importin alpha 2
Tsimbslyuk S, Stewart M, Forwood JK
To be published
Source organisms: Mus musculus , Homo sapiens
Assembly composition: protein/protein complex
Assembly name:
Nuclear factor NF-kappa-B p52 subunit and Importin subunit alpha-1
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-273855 (Preferred)
search this ID
crystal structure of the C-terminal domain of p100/NF-kB2
Tao ZH, Huang DB, Fusco A, Gupta K, Ware CF, Duynne GV
Proc Natl Acad Sci U S A
(2014)
[PMID: 25349408 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Bound ligands:
SO4
Assembly name:
NF-kappaB transcription regulation complex, p52/p52
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-169463 (Preferred)
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Crystal structure of the dimerization domains p52 and RelB
Vu D, Huang DB, Ghosh G
J Mol Biol
(2013)
[PMID: 23485337 ]
Source organism: Mus musculus
Assembly composition: protein/protein complex
Bound ligands:
SO4
Assembly name:
Nuclear factor NF-kappa-B p52 subunit and Transcription factor RelB
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-170084 (Preferred)
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HUMAN NF-KAPPA-B P52 BOUND TO DNA
Cramer P, Larson CJ, Verdine GL, Muller CW
EMBO J
(1997)
[PMID: 9384586 ]
Source organisms: Synthetic construct, Homo sapiens
Assembly composition: DNA/protein complex
Assembly name:
NF-kappaB transcription regulation complex, p52/p52 and DNA
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-113392 (Preferred)
search this ID

Entries 1 to 10 of 13